Midterm! Flashcards

0
Q
Which parts of the spleen counts for activation of the immune competent cells?
A. Red pulp
B. Cortical pulp
C. Medullar pulp
D. White pulp
A

White pulp

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1
Q

True or False. Rise in body temperature is the result of production of pyrogens

A

True

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2
Q
Which one of the following theories of antibody synthesis is established by professor Burnet?
A. The clonal selection theory
B. Selective theory
C. Side chain theory
D. None of the above
A

A. The Clonal selection theory

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3
Q
The role of the microphage during an antibody response is to...
A. Make antibody
B. Lyse virus infected cells
C. Activate T-cells
D. Present antigen
E. C and D
A

E. C and D

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4
Q
Which one of the cells is known as granular leukocytes?
A. Basophils 
B. Monocytes
C. Lymphocytes
D. Macrophages
A

A. Basophils

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5
Q

The founders of (*) cell mediated immunity and (**) humoral immunity correspondingly are…
A. * Elie Metchnikoff **Emil Von Behring
B. * Emil Von Behring ** Paul Ehrlich
C. * Lois Pasteur ** Emil Von Behring
D. * Elie Metchnioff ** Edward Jenner

A

A. Elie Metchnikoff; Emil Von Behring

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6
Q
Blood concentration of the following white blood cells is increased in the presence of parasitic infection in the body?
A. Lymphocytes 
B. Neutrophils
C. Monocytes 
D. Eosinophils
A

D. Eosinophils

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7
Q
Which of the following cells in NOT considered a phagocytic one?
A. Eosinophils
B. Monocytes
C. Mast cells 
D. Neutrophils
A

C. Mast cells

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8
Q
Which of the following is the correct name of the thymus accounting for secretion of the thymic hormone?
A. Germinal cells
B. Nurse cells
C. Medullar cells
D. Cortical cells
A

B. Nurse cells

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9
Q
Microglial cells represent which of the following cells fixated in brain tissue?
A. Lymphocytes 
B. Basophils
C. Eosinophils 
D. Macrophages
A

D. Macrophages

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10
Q
GALT is composed of lymphoid tissue in...
A. Gastrointestinal tracts 
B. Brain membrane
C. Respiratory tracts 
D. Endocardium
A

A. Gastrointestinal tracts

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11
Q
T cells are important in controlling...
A. Virus infection
B. Allergy 
C. Autoimmunity 
D. All of the above
A

D. All of the above

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12
Q
Which of the following scientists and physicians was the first to produce a vaccine for rabies?
A. Lois Pasteur
B. Edward Jenner 
C. Paul Ehrlich
D.  Emil Von Behring
A

A. Lois Pasteur

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13
Q
As the person aged, red marrow is gradually replaced by...... And the cellular activity of the marrow declines.
A. B cells
B. T cells
C. Yellow marrow 
D. B&C
A

C. Yellow marrow

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14
Q
Nonspecific host defense is associated with....
A. Feces
B. Blood
C. Pus
D. Mucous membranes
A

D. Mucous membrane

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15
Q
Leukocytes with no identifiable membrane markers, that fight against cancer cells and virally infected cells are.....
A. Plasma cells
B. B cells
C. Natural killer cells
D. Macrophage
A

C. Natural killer cells

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16
Q
Systemic signs of inflammation is....
A. Heat 
B. Swelling
C. Fever
D. All of the above
A

C. Fever

17
Q
An example of a nonspecific mechanical barrier to infection is...
A. Coughing 
B. Sneezing
C. Cilia in respiratory tract
D. All of the above
A

D. All of the above

18
Q
Which nonspecific host defense is associated with the trachea? 
A. Lacrimation
B. Ciliary lining
C. Lactic acid
D. None of the above
A

D. None of the above

19
Q
Which part of the lymph node has both T cells and B cells?
A. Cortex 
B. Paracortex
C. Medulla
D. Red pulp
A

C. Medulla

20
Q
Which of the following is not a lymphoid tissue?
A. Spleen 
B. Thyroid gland
C. Lymph node 
D. GALT
A

A. Spleen

21
Q
Which of the following inflammatory signs specifies swelling?
A. Tumor
B. Dolor
C. Calor
D. Rubor
A

A. Tumor

22
Q
The initial stages of T lymphocyte precursors (tymocytes) development are under the influence of \_\_\_\_\_ cytokine
A. Interleukin 7
B. Interleukin 3
C. Interleukin 4
D. B and C
A

A. Interleukin 7

23
Q
An inflammatory mediator that stimulates vasodilation is....
A. Prostaglandins
B. Collagen
C. Complement
D. Interferon
A

A. Prostaglandins

24
Q
............... Is an exogenous pyrogen
A. Interleukin 1
B. Complement
C. Interferon
D. Endotoxin
A

D. Endotoxin

25
Q

Immunologic memory refers to the ability of the immune system to….
A. Recognize millions of different antigens
B. Reacts with millions of different antigens
C. Migrate from the blood vessel into the tissues
D. Recall a previous immune response

A

D. Recall a previous immune response

26
Q
Which subset of WBCs account for acquired specific immunity?
A. Macrophages 
B. T cells
C. B cells
D. Both B and C
A

B. T cells

27
Q
In humans, the B cells mature is the (*) .... And T cells mature in the (**).... 
A. *GALT **liver
B. *bursa **thymus
C. *bone marrow **thymus
D. *lymph nodes **spleen
A

C. Bone marrow ; thymus

28
Q
Which part of the spleen is responsible to respond to T independent antigen such as polysaccharide? 
A. PALS (periarteiolar lymphoid sheaths)
B. Marginal zone
C. Germinal center
D. Red pulp
A

B. Marginal zone

29
Q
Which type of cell actually secrets antibody?
A. T cells 
B. Macrophages
C. Plasma cells
D. Monocytes
A

C. Plasma cells

30
Q

Your patient is a child who has no detectable T or B cells. The immunodeficiency is most probably the result of a defect in…
A. The thymus
B. The bursal equivalent
C. T cells-B cells interaction
D. Stem cells originating in the bone marrow

A

D. Stem cells originating in the bone marrow

31
Q
What is the function of Th-2 cells? 
A. B cells activation and antibody production 
B. Complement activation
C. Type four allergic reaction 
D. Cytotoxic activity
A

A. B cell activation and antibody production

32
Q
A bi-lobed organ that rests above the heart and it's size is greatest proportionately at birth and it continues to grow and increase its activity until puberty is...
A. Liver
B. Thymus
C. Bone marrow 
D. Lymph nodes
A

B. Thymus

33
Q
In which lymphatic organ antigens will be presented to T cells and B cells?
A. Liver
B. Thymus
C. Bone marrow 
D. Spleen
A

D. Spleen

34
Q
Which of the following T cells is a major cytokine-producer? 
A. T helper (TH) cells
B. T cytotoxic (TC) cells
C. T suppressor (TS) cells 
D. Delayed hypersensitivity (TD) cells
A

A. T helper (TH) cells

35
Q
Which of the following white blood cells can initiate long lasting immunity?
A. Memory T cells
B. Memory B cells 
C. memory T and B cells
D. Dendritic cells
A

C. Memory T and B cells

36
Q
Thromopoietin stimulates development of....
A. T cells
B. Macrophages 
C. Plasma cells 
D. Platelets
A

D. Platelets

37
Q

Important characteristics of acquired (adaptive) responses are….
A. Having the ability to respond to millions of different antigens
B. Having actions that are specifically directed against the antigens
C. Having the ability to respond many years after the initial exposure
D. A, B, &C

A

D. A, B, &C

38
Q
IFN (gamma) can be produced by...
A. T cells 
B. Macrophages
C. Natural killer cells
D. A and C
A

D. A and C

39
Q
Gastric secretions secrete..... environment in the stomach that inhibits the growth of and kills many microbes.
A. A low temperature
B. A low pH (2)
C. A high pH 
D. A high temperature
A

B. A low pH (2)