Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Immuno > Exam 2 > Flashcards

Exam 2 Flashcards

0
Q 
The T-helper (Th) cells produce\_\_\_\_\_\_\_, that stimulates a general increase in the activity of committed B-cells
A. Interleukin-2
B. Interleukin-1
C. Interleukin-7
D. Interleukin
A

A. Interleukin-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q 
This antibody has the lowest percent in blood circulation and has harmful effect.
A. IgA
B. IgE
C. IgD
D. B and C
A

B. IgE
* IgE- 05% IgA- 10-15% IgD- .2% IgM- 5-10% IgG- 80%
GAMDE
IgG>IgA>IgM>IgD>IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q 
Because of the lack if Bc receptor on phagocytic cells, this antibody cannot function as opsonin
A. IgA
B. IgE
C. IgG
D. IgM
A

D. IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q 
A cytokine, interleukin-1 produce by \_\_\_\_\_\_\_, activities the T-helper cells (mature&proliferate)
A. Macrophage
B. T4 lymphocyte
C. T8 lymphocyte
D. Platelets
A

A. Macrophage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

C3 is not a stable molecule and is constantly undergoing spontaneous low level activation. Spontaneous activation of C3 is most likely to happen on cell surface components.
A. True
B. False

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q 
Cell associated cytotoxicity occurs in which of the following hypersensitivity reactions?
A. Type 1
B. Type 2
C. Type 3
D. Type 4
A

B. Type 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q 
Mechanisms for cell damage in type II hypersensitivity
A. Classical complement cascade 
B. Natural killer cells
C. Opsonization
D. All of the above
A

D. All of the above

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q 
Incompatible blood transfusion could induce a hemolytic reaction that results in intravascular lysis of RBCs, and release of \_\_\_\_\_ from lysed cells
A. Hemolysin
B. Hemoglobin 
C. Opsonin
D. A and B
A

B. Hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q 
Antibodies bind to antigens and cause \_\_\_\_\_\_
A. Opsonization 
B. Agglutination
C. Neutralization
D. All the above
A

D. All the above

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q 
\_\_\_\_\_\_ regions on both chains of antibodies are responsible of fixing complement
A. Constant (C)
B. Domain
C. Variable (V)
D. Disulfide
A

C. Variable (V)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q 
Which of the following immunoglobulin is NOT able yo activate the complement system by classic pathway?
A. IgD
B. IgG
C. IgM
D. All the above
A

A. IgD

* IgD & IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q 
C1 component of complement has a receptor for which of the following fragments of the immunoglobin?
A. F – a B
B. F – C
C. Both F – a B and F – C
D. None of the above
A

B. F – C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q 
Which of the following components of the complement primarily undergoes activation in the lectin complement pathway?
A. C1
B. C2
C. C5
D. C3
A

D. C3

* lectin pathway = C3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q 
T4 (helper) cells are able to recognize foreign antigens in combination of which of the following classes of the major Histocompatibility complex?
A. Class one molecules
B. Class two molecules
C. Both classes one and two
D. None of the above
A

B. Class two molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q 
A fetus can produce immunoglobulins of which of the following classes?
A. IgA
B. IgD
C. IgE
D. IgG
E. IgM
A

E. IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q 
This component of complement that is produced during complement activation, is the most important opsonin for activation of phagocytic cells
A. C1
B. C5
C. C2
D. C3
A

B. C5

16
Q 
Which of the following components of complement is called anaphylatoxin? 
A. C5a
B. C3b
C. C3a
D. A and C
A

D. A and C

17
Q 
And secondary antibody response is the antibodies of which of the following classes of immunoglobulin is produced most?
A. IgA
B. IgD
C. IgE
D. IgG
E. IgM
A

D. IgG
* secondary IgG - 80%
Primary IgM - 5-10%

18
Q 
Which of the following is an antigen presenting cell?
A. T4 – lymphocyte
B. T8 – lymphocyte
C. Denritic cells
D. Platelets
A

C. Denritic cells

19
Q 
Deficiency of low level \_\_\_\_\_\_\_ can cause recurrent bacterial infection (pyogenic bacteria)
A. C1
B. C2
C. C4
D. C3
E. All of the above
A

E. All of the above

20
Q 
Culmination of which of the following components of complement is called membrane attack complex?
A. C4aC3aC5a
B. C1sC2bC3b
C. C5B, C6B, C7B, C8B, C9B
D. C4bC2aC3b
A

C. C5B, C6B, C7B, C8B, C9B,

* MAC = 5-9

21
Q 
In generation of atopic hypersensitivity, fixation of IGE to \_\_\_\_\_\_\_\_ occurs via the FC fragment
A. Mast cells
B. Basophils
C. T cells
D. A or B
A

D. A or B

* IgE –> mass cells and basophils via Fc

22
Q 
The human major Histocompatibility complex (MHC) IS COMPOSED OF A CLUSTER OF GENES LOCATED \_\_\_\_\_\_\_
A. Plasmid
B. Chromosome 6
C. Ribosome
D. None of the above
A

B. chromosome 6

23
Q 
The human major histocompatibility complex (MHC) is also known as...
A. Antibody – antigen complex
B. Complement fixation complex
C. Human leukocyte antigen (HLA)
D. A and B
A

C. human leukocyte antigen (HLA)

24
Q 
Theoretically, type \_\_\_\_\_ blood can be donated to all people because it lacks \_\_\_\_\_ 
A. AB, antibodies
B. O, antigens
C. AB, antigens
D. O, antibodies
A

B. O, antigens

25
Q 
An example of type one hypersensitivity is \_\_\_\_\_\_
A. Serum sickness
B. Contact dermatitis
C. Incompatible blood transfusions
D. Atopy
A

D. Atopy
* serum sickness: type III
Contact dermatitis: type IV
Incompatible blood transfusion: type II

26
Q

Type to hypersensitivity are due to….
A. IGE reacting with mast cells
B. Activation of cytotoxic T cells
C. IgG-allergen complexes that clog epithelial tissue
D. complement – induced lysis of cells in the presence of antibodies

A

B. Activation of cytotoxic T cells

27
Q

Properties of haptons include:
A. Immunogenicity and reactivity (ability to bind)
B. Reactivity but no immunogenicity
C. Immunogenicity but no reactivity
D. Chemical complexity and macromolecular nature

A

B. reactivity but no immunogenicity

28
Q 
An antigen that occurs in various tissues of the same species is referred to as: 
A. Alloantigen 
B. Hetrophilic antigen 
C. Autoantigen
D. Superantigen
A

A. Alloantigen

29
Q 
Which type of these allergies is T-cell mediated?
A. Type I
B. Type II
C. Type III 
D. Type IV
A

B. Type II

30
Q 
Production of IgG is involved in \_\_\_\_\_
A. Immune Complex disease
B. Hayfever
C. Asthma 
D. Both B and C
A

A. immune complex disease

31
Q 
Call molecules that have anti-genic determinant group and are not immunogenic
A. Penicillin
B. Catechol
C. Protein
D. A and B
A

D. A and B

32
Q

Some bacterial toxins are superantigens. Presence of superantigens in an infection blocks activation of T cells
A. True
B. False

A

B. False

33
Q 
B cells to respond to antigens such as...
A. Protein
B. Polysaccharide
C. Carbohydrate
D. All of the above
A

D. All of the above

Immuno (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions