MIDTERM 3

Question 1

irradiation inside body that requires low dose for measurable response

Answer 1

in vivo

Question 2

irradiation outside the body (req. high doses for measurable effect)

Answer 2

in vitro

Question 3

Major effects of irradiation of macromolecules

Answer 3

Main chain scission
Cross linking
Point lessions

Question 4

Major effects of irradiation of macromolecules where after irradiation, spur-like structures extend off main chain; increases viscosity of solution

Answer 4

Cross linking

Question 5

Major effects of irradiation of macromolecules where breakage of back bone long chain macromolecule; reduces size & viscosity solution

Answer 5

Main chain scission

Question 6

Major effects of irradiation of macromolecules where disruption on chemical bond; not detectable causes minor modification

Answer 6

Point lessions

Question 7

where does point lessions occur

Answer 7

low dose radiation

Question 8

What does cellular damage of radiation result in

Answer 8

Stochastic effect

Question 9

critical to cell survival & reproduction

Answer 9

protein and nucleic acid synthesis

Question 10

manufactured by translation of genetic code (Transcription, Transfer, Translation)

Answer 10

protein

Question 11

DNA Synthesis
G1 interphase- accumulates in nucleus: deoxyribose, phosphate , base molecules