Midterm 3 Flashcards
How many pairs of chromosomes does each human have?
23 = 46 chromosomes total
- 22 pairs of chromosomes (autosomes) and 1 pair of sex chromosomes
- Each pair contains 2 chromosomes, 1 from each parent
What are gametes?
Ovum (eggs) and sperm
- Contain 23 chromosomes
- When egg and sperm fertilize, it contains 23 pairs
What parent determines sex?
Father
- Females are XX, male is XY
What are disorders of sexual development?
Intersex
- chromosomal sex is inconsistent with phenotypic sex (reproductive organs)
- Some individuals have both female and male anatomy
What is prenatal development controlled by?
Genes
- Leads to normal development or abnormal development
- Sensitive to nutrients, viruses, drugs, physical activity
What is embryonic development?
Conception to 8 weeks
- Differentiation of cells to form specific tissues and organs
- Limbs formed and heartbeat begins at 4 weeks
- Human form noticeable at 8 weeks
- Eyes, ears, nose, mouth, fingers and toes are formed
- Size of a bean
What is fetal development?
8 weeks to birth
- Growth by hyperplasia (increase in cell number) and hypertrophy (cell size)
- Cephalocaudal (head to toe) - head and facial features grow fastest, followed by upper body and slower growing lower body
- Proximodistal (near to far) - trunk advances first, then nearest part of limbs, then distal parts of limb
What is fetal nourishment?
Oxygen and nutrients diffuse between fetal and maternal blood in placenta
- Poor maternal health status can affects fetus
What is genetic abnormal prenatal development?
Trisomy 21 - Down syndrome
What is structural abnormal prenatal development?
Congenital heart defects
- Often no clear cause
- Genetic, exposures, diet, maternal disease
What are congenital abnormalities?
Wide range of abnormalities of body structure or function that are present at birth and are of prenatal origin
- Can be genetic or external
What is an external exposure abnormal prenatal development?
Teratogen - agent or factor that causes abnormal prenatal development upon exposure
ex. Rubella virus - harmful if exposed during first 4 weeks. Earlier exposure = more serious abnormalities
What are external causes of abnormal development?
Pressure, temperature, Xrays, pollutants
What is physical growth?
quantitative increase in size
What is development?
Continuous process of change in functional capacity
- ability to live, move and excel in the world
- Humans are always developing but change may be more or less noticeable at certain points
What is Maturation?
developmental process leading to a state of full function
- An adult like state
- Maturation implies progress toward physical maturity, state of optimal functional integration of individual’s body systems and ability to reproduce
What figure does growth follow?
Sigmoid (S)
- Rapid growth after birth, followed by gradual but steady growth during childhood, then rapid growth during early adolescence
When is peak height velocity? When does growth stop?
Girls
- Peak height velocity - 11.5-12 years
- Tapers off around 14, ends around 18
Boys
- Peak height velocity - 13.5-14 years
- Tapers off around 17, ends around 18
What pattern does weight follow?
Sigmoid
What is weight susceptible to?
Diet and exercise
When is peak weight velocity?
Boys - 2.5-5 months
Girls - 3.5-10.5 months
What is menarche?
First menstruation
Why is the age of menarche decreasing?
Diet, sedentary behaviour, low physical activity
- Physical activity reduces estrogen
What are factors associated with early menarche?
Risky sexual behaviour, Obesity, Diabetes, Cardiovascular disease, Breast cancer
What is the Tanner and Marshall scale?
Male development
What are sex differences in brain development?
Prefrontal cortex matures 2 years later
- Impulse control, planning, self-regulation, decision-making, judgment
Cerebellum reaches full size for girls at 11 and 15 for boys
- Modulates emotional, cognitive and regulation capacity
What are the sex differences in play?
Boys - Weapons and competition, play fighting
Girls - Domestic toys and play
What are the sex differences in aggression in play?
Girls - relational aggression - intentional harm caused to others by damaging social relationships or feelings of peer acceptance
Boys - physical aggression
What are the physiological assessments of maturation?
Ossification (hardening) of bones
Why can height decrease older adulthood?
Compression of cartilage pads
Osteoporosis - bone density loss
When does ossification begin?
6th or 7th week
How many neutrons are created every minute? (prenatal)
250,000
What do compact and spongy bone develop from?
Sheets of connective tissue
Where does growth in bone length occur?
Secondary ossification centres - epiphyseal plates
When does muscle mass stop increases?
Girls - age 13
Boys - 17 years