Midterm 2: Chapters 6 and 8 Flashcards
the cardiovascular system: what are the major functions?
- delivers o2, nutrients
- removes co2, other wastes
- transports hormones, other molecules
- temperature balance and fluid regulation
- acid-base balance
- immune function
the cardiovascular system: what are the three major circulatory elements?
- a pump (heart)
- channels or tubes (blood vessels)
- a fluid medium (blood)
_____ grenerates pressure to drive blood through vessels.
heart
_____ must meet metabolic demands.
blood flow
how does the blood flow through the heart?
from superior/inferior vena cavae -> RA -> tricuspid valve -> RV -> pulmonary valve -> pulmonary arteries -> lungs -> pulmonary veins -> LA -> mitral valve -> LV -> aortic valve -> aorta
right side of the heart is the ?
pulmonary circulation
pumps deoxygenated blood from body to lungs
left side of the heart is the?
systemic circulation
pumps oxygenated blood from lungs to body
myocardium itself needs blood and blood comes from?
- right coronary artery supplies right side of heart
- left (main) coronary artery supplies left side of heart
whenever you refer to myocardium you are referring to the ?
heart
myocardium: _____ muscle
cardiac
what are some left ventricle (LV) characteristics?
- must pump blood to entire body
- thickest walls (hypertrophy)
- LV hypertrophies with exercise and with disease
- but exercise adaptations versus disease adaptations very different
skeletal muscle cells are?
- large, long, unbranched, multinucleated
- intermittent, voluntary contractions
- Ca2 released from SR
myocardial cells are?
- small, short, branched, one nucleus
- continuous, involuntary rhythmic contractions
- calcium-induced calcium release
myocardial cells have one one fiber type similar to type I of skeletal muscle that include?
- high capillary density
- high number of mitochondria
- striated
cardiac muscle fibers connected by regions called?
intercalated discs
_____: hold cells together.
desmosomes
____: rapidly conduct action potentials
gap junctions
what are the two main pathways of the heart?
intrinsic and extrinsic
intrinsic control of heart activity means the heart controls its self, this is also known as?
spontaneous rhythmicity
_____: special heart cells generate and spread electrical signal.
spontaneous rhythmicity
what are the electrical signals that the spontaneous rhythmicity spread?
- sinoatrial (SA) node
- atrioventricular (AV) node
- AV bundle (bundle of His)
- purkinje fibers
extrinsic control of heart activity consists of?
parasympathetic and sympathetic control
heart activity that is parasympathetic controls?
- decreases force of contraction
- decreased HR below intrinsic HR
( intrinsic HR: 100 beats/min, normal resting HR (RHR): 60 to 100 beats/min, elite endurance athlete: 35 beats/min)
heart activity that is sympathetic controls?
- increases force of contraction
- increases HR above intrinsic HR
- determines HR during physical, emotional stress
- maximum possible HR: 250 beats/min
what is the cardiac cycle?
all mechanical and electrical events that occur during one heartbeat
the cardiac cycle consists of?
diastole and systole
_____: relaxation phase
- chambers fill with blood
- twice as long as systole
diastole
_____: contraction phase
systole
during the cardiac cycle ventricular systole is 1/3 of the cardiac cycle time and what else is occurring?
- blood ejected
- during systole, blood ejected out, but some leftover
- blood leftover in ventricle = end-systolic volume (ESV)
during the cardiac cycle ventricular diastole is 2/3 of the cardiac cycle time and what else is occurring?
- fill 70% passively, remaining 30% by atrial contraction
- at end, blood in ventricle = end-diastolic volume (EDV)
_____: volume of blood pumped in one heartbeat
stroke volume (SV)
ejection fraction (EF): ?
% of EDV that was SV
- SV / EDV = EF
- 60 mL / 100 mL = .6 = 60%
(normal for healthy, active young adult at rest)
- clinical index of heart contractile function
_____: total volume of blood pumped per minute
- Q = HR * SV (use L/min)
- resting cardiac output (4.2 to 5.6 L/min)
(average total blood volume: 5 L, therefore, total blood volume circulate once every min)
cardiac output
what is involved in the vascular system?
arteries, arterioles, capillaries, venues, veins
_____: carry blood away fro heart.
arteries
____: control blood flow, and waste exchange
arterioles
____: site of nutrient and waste exchange
capillaries
____: collect blood from capillaries
venules
_____: carry blood from venues back to heart
veins
_____: pressure exerted by blood on arterial walls.
blood pressure (BP)
_____:
- highest pressure in artery (during systole)
- top number, ~ 110 to 120 mmHG
systolic pressure (SBP)