Midterm 2 Flashcards
The Hardy-Weinberg Equilibrium requirements
1) No mutations
2) No natural selection
3) No gene flow (no migration)
4) No genetic drift (which requires an infinitely large population size)
5) Random mating
Mendel’s Law of Segregation
When any individual produces gametes, the two copies of a gene separate so that each gamete receives only one copy
Mendel’s Law of Independent Assortment
alleles of different genes assort independently of one another during gamete formation, haploid gametes
Mitosis
Duplicate, all cells except sex cells, identical
Meiosis
Two stages of duplication, not identical to parent cell, only sex cells
Types of Dominance
Complete Dominace, Incomplete Dominance, Codominace
Complete Dominance
A single dominant allele produces the dominant phenotype. The homozygous dominant and heterozygous genotypes have the same phenotype
Incomplete Dominance
the heterozygote phenotype is intermediate between the two homozygous phenotypes
Codominance
the heterozygote shows both the homozygous phenotypes
Recombination
gene crossing over
Linkage
only crossovers happening in a small region
* Recombinant chromosomes do form, but not very often!
Recombination Frequency - eq.
recombinant frequency = recombinants / total offspring
Linkage Mapping
Determining the recombination frequency for numerous genes allows mapping each genes’ location on the chromosomes
Sex-linked inheritance
Females are less likely to exhibit sex-linked inheritance but can be carriers
Pleiotropy
When one gene affects multiple traits
Polygenic Inheritance
One trait is controlled by many genes
Environmental Influences
pH, food abundance, temperature, etc.
Epistasis
When multiple genes interact to determine the phenotype
allele frequencies
the proportion of a particular allele across all individuals, or in the gametes produced by those individuals
- dominant allele
- recessive allele
Genotype frequencies
the proportion of individuals with a particular genotype in a population homozygous dominant homozygous recessive heterozygous hemizygous
Allele frequencies equation
p(dominant) +q(recessive) = 1
Genotype frequencies equation
two alleles -> (p+q)^2
p^2 + 2pq + q^2 = 1
p^2 ( Homozygous dominant) + 2pq (Heterozygous) + q^2 (Homozygous recessive) = 1
three alleles -> (p+q)^3
What is Mutation?
BIS 2A
- Substitution
- Insertion and deletions
- Chromosomal Rearrangements
ex. unequal crossover
Gene Flow (migration)
transfer of alleles through movement of fertile individuals of their gametes
- immigration - into pop
- emigration - out of pop
Gene Flow vs. Migration
Sessile organisms migrate when individuals post fertilization can move before settling down
Inbreeding
mating between relatives with similar genotypes
ex. Charles 2 of Spain
Outbreeding
mating between unrelated individuals with dissimilar genotypes
Stabilizing selection
Individuals nearest the mean have the highest fitness. the mean stays the same, variation is reduced
directional selection
individuals at one extreme have the highest fitness. Mean trends toward that extreme
Disruptive selection
individuals at both extremes have higher fitness than the mean. Variation is increased, a bimodal pattern emerges
ex. Biston betularia