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Pharma 2 > midterm 2 > Flashcards

midterm 2 Flashcards

1
Q

Which agent has activity against fleas?

A: Moxidectin
B: Amitraz
C: Both of them
D: None of them

A

D: None of them

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2
Q

Which species is sensitive to fipronil?

A: Ferret
B: Honey bee
C: Both of them
D: None of them

A

D: None of them

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3
Q

Which agent kills fleas most quickly?

A: Fipronil
B: Imidacloprid
C: Methoprene
D: Amitraz

A

B: Imidacloprid

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4
Q

Izoxasolines are authorised for.

A: Dog
B: Laying hen
C: Both
D: None

A

C: Both

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5
Q

midacloprid can be given..

A: Collar
B: Injection
C: Both
D: None

A

A: Collar

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6
Q

MDR-1 gene mutation is more frequent in this dog breed:

A: German Shepard
B: Bobtail
C: the mutation dosent occur in these breeds
D: its similar in both of them

A

A: German Shepard

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7
Q

What is the mechanism of action of izoxasolines?

A: GABA receptor antagonism
B: GABA receptor agonism
C: Acetylcholine receptor agonism
D: Acetylcholinesterase inhibition

A

A: GABA receptor antagonism

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8
Q

What is the mechanism of action of neonicotinoids?

A: Acetylcholine receptor agonism
B: Acetylcholinesterase inhibition
C: GABA receptor anatagonism
D: Na channel blocking

A

A: Acetylcholine receptor agonism

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9
Q

Which macrocyclic lactone is effective against demodicosis?

A: Selamectin
B: Amitraz
C: Both of them
D: None of them

A

D: None of them

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10
Q

Which is true for amitraz?

A: It dosent inhibit dopamine reuptake drom synaptic gap in mammals
B: Both of them
C; Toxic for bees under 10􏲁C
D: None of them

A

B: Both of them

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11
Q

Pyrethroids can be given in..

A: IM injection
B: Washing solution
C: Both of them
D: None of them

A

D: None of them

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12
Q

Which is an effective antidote of diazinon poisoning?

A: None of them
B: Piriproxifen
C: Atipamezole
D: Both of them

A

A: None of them

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13
Q

Which species is sensitive to pyrethroids?

A: cat
B: both of them
C: fish
D: none of them

A

B: both of them

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14
Q

Pyrethroids can be given in..

A: Spot on
B: Both of them
C: Collar
D: None of them

A

B: Both of them

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15
Q

Which can be an antidote of pyrethroid poisoning?

A: Pralidoxime
B: Atipamezole
C: None of them
D: Atropine

A

C: None of them

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16
Q

In cats, how can pyrethroids be given?

A: Spot on
B: Both of them
C: Collar
D: None of them as they are toxic to cats

A

C: Collar

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17
Q

. What is characteristic to the mechanism of action of deltamethrin?

A: Knock-down effect
B: Both of them
C: Repellent effect
D: None of them

A

A: Knock-down effect

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18
Q

How can amitraz be given?

A: Collar
B: Washing solution
C: Both of them
D: None of them,

A

C: Both of them

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19
Q

How can praziquantel be given?

A: IV injection
B: Topically
C: Both of them
D: None of them

A

D: None of them

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20
Q

Ectoparasiticides agents can be given..

A: Both of them
B: Orally
C: In Injection
D: None of them

A

B: Orally

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21
Q

Ectoparasiticides agents can be given..

A: both of them
B: orally
C: topically
D: none of them

A

A: both of them

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22
Q

Which agent has repellent effect?

A: Pyrantel
B: Doramectin
C: None of them
D: Both of them

A

C: None of them

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23
Q

This mechanism leads to the selective toxicity of ectoparasiticide agents:

A: none of them
B: quick and excellent absorption in the host animal
C: high free plasma concentration is the host animal
D: both of them

A

A: none of them

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24
Q

Which substance is an organophosphate from the following?

A: phoxim
B: piripol
C: both of them
D: none of them

A

A: phoxim

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25
Q

Juvenile hormone analogues are effective against this arthropod:

A: Tick
B: Flea
C: Both of them
D: None of them

A

B: Flea

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26
Q

What is the mechanism of action of propoxur?

A: Reversible inhibition of acetylcholinesterase
B: irreversible inhibition of acetylcholinesterase
C: Acetylcholine receptor agonist
D: Acetylcholine receptor antagonist

A

A: Reversible inhibition of acetylcholinesterase

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27
Q

How can levamisole be given?

A: IV
B: SC
C: Both of them
D: None of them

A

B: SC

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28
Q

Which agent can be used to treat flea infection in dogs?

A: Pyrantel
B: Imidacloprid
C: Both of them
D: None of them

A

B: Imidacloprid

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29
Q

What is the mechanism of action of organophosphates?

A: Reversible inhibition of acetylcholinesterase
B: Irreversible inhibition of acetylcholinesterase
C: Acetylcholine receptor agonist
D:Acetylcholine receptor antagonist

A

B: Irreversible inhibition of acetylcholinesterase

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30
Q

Which is characteristic to the spectrum of oxfendazole?

A: Anticestodal effect
B: Antinematodal effect
C: Both of them
D: None of them

A

C: Both of them

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31
Q

Which species is sensitive to levamisole?

A: Horse
B: Turkey
C: Chameleon
D: Sheep

A

A: Horse

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32
Q

What is characteristic to the mechanism of action of macrocyclic lactones?

A: inhibition of microtubules polymerzation
B: Irreversible inhibition of the acetylcholinesterase
C: Decreased ATP production
D: GABA receptor agonism

A

D: GABA receptor agonism

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33
Q

What is characteristic to the spectrum of febantel?

A: Activity against giardia
B: Both of them
C: Activity against roundworm
D: None of them

A

C: Activity against roundworm

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34
Q

Resistance to benzimidazoles occurs in these helminths

A: Canine taenia helminths
B: Both of them
C: Equine strongylus helminths
D: None of them

A

C: Equine strongylus helminths

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35
Q

What is characteristic to the spectrum of triclabendazole?

A: Anticestodal effect
B: Antitrematodal effect
C: Antinematodal effect
D: All of them

A

B: Antitrematodal effect

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36
Q

How can benzimidazoles be given?

A: In premix
B: In intraruminal bolus
C: Both of them
D: None of them

A

C: Both of them

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37
Q

What is characteristic to the spectrum of fenbendazole?

A: Hookworms
B: Both of them
C: Tapeworms
D: None of them

A

C: Tapeworms

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38
Q

Which agent is a prodrug from the following?

A: Albendazole
B: Oxfendazole
C: Both of them
D: None of them

A

D: None of them

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39
Q

Which agent has the longest duration of action is administered in in therapeutic dosage?

A: Afoxolaner
B: Fluralaner
C: Sarolaner
D: Their duration is similar

A

A: Afoxolaner

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40
Q

Which is chitin inhibitor from the following?

A: Lufenuron
B: Methoprene
C: Both of them
D: None of them

A

A: Lufenuron

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41
Q

Which us an IGR from the following?

A: Both of them
B: Novaluron
C: Methoprene
D: None of them

A

A: Both of them

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42
Q

midacloprid can be given.

A: Spot on
B: Tablet
C: Both of them
D: None of them

A

A: Spot on

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43
Q

which agent has activity against fleas?

A: Selamectin
B: Imidacloprid
C: None of them
D: Both of them

A

D: Both of them

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44
Q

Fluralaner is effective against..

A: Flea
B: Both of them
C: Demodex spp
D:None of them

A

B: Both of them

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45
Q

Which macrocyclic lactone is effective against scabies?

A: Ivermectin
B: Milbemycin oxime
C: Doramectin
D: None of them

A

A: Ivermectin

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46
Q

Izoxasolines can cause these side effects in case of overdose:

A: Ataxia, muscle weakness, flaccid paralysis
B: Ataxia, tremor, spasm
C: Sedation, hypothermia
D: Emesis, bronchoconstriction, bradycardia

A

B: Ataxia, tremor, spasm

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47
Q

Fipronil is effective against this parasite:

A: Demodex canis
B: None of them
C: Both of them
D: Ctenocephalides felis

A

B: None of them

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48
Q

Which species is sensitive to fipronil?

A: Cat
B: Dog
C: None of them
D: Rabbi

A

D: Rabbit

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49
Q

Which can be the side effect of amitraz?

A: Hypoglycaemia
B: Both of them
C: Paralytic ileus
D: None of them

A

C: Paralytic ileus

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50
Q

Which side effect is characteristic to organophosphate?

A: Spasm, coma
B: All of them
C: Urination, lacrimation
D: Miosis

A

B: All of them

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51
Q

How can amitraz be given?

A: Chewing tablet
B: Injection
C: None of them
D: Both of them

A

C: None of them

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52
Q

Propoxur poisoning causes these symptoms:

A: Mydriasis
B: Tremor, spasms
C: Both of them
D: None of them

A

D: None of them

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53
Q

Pyrethroids can be given in..

A: SC injection
B: None of them
C: Chewing tablet
D: Both of them

A

B: None of them

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54
Q

which side effect is characteristic to organophosphates?

A: Both of them
B: Difficult breathing, bradycardia
C: Flaccid paralysis, ataxia
D: None of them

A

B: Difficult breathing, bradycardia

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55
Q

What is characteristic to the mechanism of action of amitraz?

A: Alpha 2 receptor antagonism
B: Both of them
C; Inhibition of octopamine reuptake from synaptic gap
D: None of them

A

C; Inhibition of octopamine reuptake from synaptic gap

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56
Q

drug can be used for the treatment of pyrethroid poisoning?

A: Midazolam
B: Intralipid
C: Both of them
D: None of them

A

C: Both of them

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57
Q

Flumethrin is effective against this parasite:

A: Phlebotomus spp.
B: Both of them
C: Varroa destructor
D: None of them

A

C: Varroa destructor

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58
Q

Diazinon is metabolised to … in the body

A: Diazoxon
B: Coumaphos
C: Both of them
D: None of them

A

A: Diazoxon

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59
Q

Which substance is an organophosphate from the following?

A: None of them
B: Propoxur
C: Dinotefuran
D: Both of them

A

A: None of them

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60
Q

Praziquantel can be used against the following helminth:

A: Strongylus species
B: Dipylidium caninum
C: Both of them
D: None of them

A

B: Dipylidium caninum

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61
Q

What is the antidote for levamisole toxicosis?

A: Epinephrine
B: Atropine
C: N-acetylcystein
D: There no antidote

A

B: Atropine

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62
Q

Praziquantel can be used against the following helminth:

A: Syngamus trachea (red tracheal worm)
B: Echinococcus granulosus
C: Both of them
D: None of them

A

B: Echinococcus granulosus

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63
Q

This mechanism leads to the selective toxicity of ectoparasiticide agents:

A: Slow absorption in the host animal
B: Higher affinity to parasites receptors
C: Both of them
D: None of them

A

C: Both of them

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64
Q

What is an effective antidote of diazinon poisoning?

A: Both of them
B: Obidoxime
C: Atropine
D: None of them

A

A: Both of them

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65
Q

Which agent can be used to treat flea infection in dog?

A: Amitraz
B: Both of them
C: Fipronil
D: None of them

A

C: Fipronil

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66
Q

Fill the sentence! …. containing organophosphate are the most toxic

A: Fluor
B: Sulfur
C: Oxygen
D: Their toxicity is similar

A

A: Fluor

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67
Q

Which is NOT an etiotropic agent from the following?

A: Doramectin
B: Dinotefuran
C: Dexamethasone
D: Diazinon

A

C: Dexamethasone

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68
Q

Macrocyclic lactone toxicosis has higher risk in this species/breed

A: Sheltie dog
B: Persian cat
D: Duroc pig
C: Gidran horse

A

A: Sheltie dog

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69
Q

Which agent is a prodrug from the following?

A: Netobimin
B: Oxfendazole
C: Mebendazole
D: Ricobendazole

A

A: Netobimin

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70
Q

Which of the following agent is an endectocide?

A: Doramectin
B: Milberrycin oxime
C: None of them
D: Both of them

A

D: Both of them

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71
Q

Which of the following agent is an endectocide?

A: Fipronil
B: Flubendazole
C: Eprinomectin
D: Fluralaner

A

C: Eprinomectin

72
Q

Which of the following agent is an endectocide?

A: Deltamethrin
B: Pyrantel
C: Albendazole
D: None of them

A

D: None of them

73
Q

Macrocyclic lactones can have the following side effects:

A: Muscle weakness, blindness, coma
B: Spastic paralysis followed by coma
C: Emesis, diarrhoea, fetal damage
D: Salivation, bronchoconstriction, bradycardia, urination

A

A: Muscle weakness, blindness, coma

74
Q

What is characteristic to the absorption of benzimidazoles from the GI tract?

A: Their absorption is excellent, bioavailability is nearly 100%
B: Their absorption is poor
C: Their absorption is moderate
D: They are not used orally

A

B: Their absorption is poor

75
Q

What is characteristic to the pharmacokinetics of levamisole?

A: Quick absorption, distribution and elimination
B: Poor absorption and distribution, barely crossing the special barriers
C: acumulation in fatty tissues, consequential long withdrawal period
D: Poor distribution, therefore SC injection is not recommended

A

A: Quick absorption, distribution and elimination

76
Q

Which of the following agent is an endectocide?

A: Flumethrin
B: Triclabendazole
C: Emodepside
D: Ivermectin

A

D: Ivermectin

77
Q

Levamisole can be used against the following helminth:

A: Hookworm
B: Lancet liver fluke
C. Echinococcus granulosus
D: All of them

A

A: Hookworm

78
Q

What is characteristic to the spectrum of oxibendazole?

A: Anticestodal effect
B: Antinematodal effect
C: Both of them
D: None of them

A

B: Antinematodal effect

79
Q

Cross-resistance is possible between levamisole and the..

A: Tetrahydropyrimidines
B: Benzimidazoles
C: Pyrethroids
D: Isoquinoline derivatives

A

A: Tetrahydropyrimidines

80
Q

How can macrocyclic lactones be given?

A: Topically
B: Via inhalation
C: Both of them
D: None of them

A

D: None of them

81
Q

How can macrocyclic lactones be given?

A: Both of them
B: Orally
C: In injection
D: None of them

A

A: Both of them

82
Q

Macrocyclic lactone toxicosis has higher risk in this species/breed:

A: Arabian horse
B: Bedlington terrier dog
C: Siamese cats
D: Border collie dog

A

D: Border collie dog

83
Q

Which substance is organophosphate from the following?

A: Both of them
B: Coumaphos
C: Dympilate
D: None of them

A

B: Coumaphos

84
Q

Which agent can be used to treat flea infection in dogs?

A: Levamisole
B: Both of them
C: None of them
D: Emodepside

A

C: None of them

85
Q

Praziquantel can NOT be used against the following helminth:

A: Echinococcus granulosus
B: Heartworm
C: Both of them
D: None of them

A

B: Heartworm

86
Q

Repellent effect is important against this parasite:

A: Mosquito
B: Tick
C: Both of them
D: None of them

A

C: Both of them

87
Q

Which agent has activity against fleas?

A: Nitenpyram
B: Afoxolaner
C: None of them
D: Both of them

A

D: Both of them

88
Q

Which is an effective antidote of coumaphos poisoning?

A: Pralidoxime
B: Epinephrine
C: Digoxin
D: Meloxicam

A

A: Pralidoxime

89
Q

Which can be the side effect of amitraz?

A: Sedation
B: Emesis
C: Both of them
D: None of them

A

C: Both of them

90
Q

Which side effect is characteristic to organophosphates?

A: Salivation, diarrhoea, emesis
B: Both of them
C: Tremors, ataxia
D: None of them

A

B: Both of them

91
Q

Organophosphates are effective against this parasite:

A: Flea
B: Both of them
C: Lice
D: None of them

A

B: Both of them

92
Q

What is characteristic to the mechanism of action of flumethrin?

A: Glutamate mediated Cl channel opening
B: Hoot footeffect
C: Both of them
D: None of them

A

B: Hoot footeffect

93
Q

Which agents has activity against fleas?

A: Amitraz
B: Both of them
C: None of them
D: Dinotefuran

A

D: Dinotefuran

94
Q

Dinetofuran is effective against the following parasite:

A: None of them
B: Scabies mite
C: Tick
D: Both of them

A

A: None of them

95
Q

Which agents can cause hyperpolarization in the parasite?

A: Both of them
B: Indoxacarb
C: Ivermectin
D: None of them

A

A: Both of them

96
Q

Which macrocyclic lactone is effective against demodicosis?

A: Diazinon
B: Fluralaner
C: All of them
D: Moxidectin

A

D: Moxidectin

97
Q

Fipronil is effective against this arthropod:

A: Dermatophagoides farina
B: Ixodes Ricinus
C: None of them
D: Both of them

A

A: Dermatophagoides farina

98
Q

Fluralaner is effective against..

A: Mosquito
B: Tick
C: Both of them
D: None of them

A

C: Both of them

99
Q

MDR-1 gene mutation is more frequent in this dog breed:

A: Border collie
B: Its similar in both of them
C: the mutation dosent occur in these breeds
D: Australian shepherd

A

B: Its similar in both of them

100
Q

Indoxacarb is effective against the following parasite:

A: Flea
B: Tick
C: Both of them
D: None of them

A

A: Flea

101
Q

Amitraz is effective against this parasite:

A: Tick
B: Demodex spp.
C: Both of them
D: None of them

A

C: Both of them

102
Q

Which agent has activity against fleas?

A: Ivermectin
B: Both of them
C: None of them
D: Indoxacarb

A

D: Indoxacarb

103
Q

Which is a systemic ectoparasiticide agent from the following?

A: Albendazole
B: Afoxolaner
C: Both of them
D: None of them

A

D: None of them

104
Q

Dinetofuran is effective against the following parasite:

A: Flea
B: Demodex spp.
C: Both of them
D: None of them

A

A: Flea

105
Q

Enterohepatic circulation is characteristic to this drug:

A: Sarolaner
B: Fluralaner
C: Afoxolaner
D: Lotilaner

A

B: Fluralaner

106
Q

What are the symptoms of permethrin poisoning?

A: Hyperthermia
B: Tremor
C: Both of them
D: None of them

A

B: Tremor

107
Q

What can be the side effect of amitraz?

A: Tachypnoea
B: Both of them
C: Bradycardia
D: None of them

A

C: Bradycardia

108
Q

Which side effect is characteristic to organophosphates?

A: Mydriasis
B: None of them
C: Bronchoconstriction, tachycardia
D: Both of them

A

B: None of them

109
Q

How can diazinon be neutralised if it gets on the skin?

A: With soap and water
B: With concentrated alcohol
C: With both of them
D: With none of them

A

A: With soap and water

110
Q

How can praziquantel be given?

A: SC injection
B: Both of them
C: Orally
D: None of them

A

B: Both of them

111
Q

Which of the following agent belongs to the imidazotiazoles?

A: Levamisole
B: Praziquantel
C: Pyrantel
D: Fenbendazole

A

A: Levamisole

112
Q

Macrocyclic lactone toxicosis has higher risk in this species:

A: Some dog breeds
B: Some cattle breeds
C: None of them

A

B: Some cattle breeds

113
Q

What is characteristic to the mechanism of action of benzimidazoles?

A: Inhibition of microtubules polymerisation
B: Inhibition of the GABA-mediated chloride ion channels
C: Both of them
D: None of them

A

A: Inhibition of microtubules polymerisation

114
Q

Which dog breed is sensitive to levamisole?

A: Kuvasz
B: Chihuahua
C: Dobermann
D: West highland white terrier

A

A: Kuvasz

115
Q

Which agent is a prodrug from the following?

A: Febantel
B: Flubendazole
C: Oxibendazole
D: Albendazole

A

A: Febantel

116
Q

What is characteristic to the mechanism of action of benzimidazoles?

A: None of them
B: Agonism of the nicotinic acetylcholine receptor
C: Reversible inhibition of the acetylcholinesterase
D: Both of them

A

A: None of them

117
Q

How does humidity affect the toxicity of diazinon?

A: Increases
B: Decreases
C: Dosent affect
D: Depending on the level of humidity, it can increase or decrease

A

A: Increases

118
Q

Which agent is a prodrug from the following?

A: Febantel
B: Flubendazole
C: Oxibendazole
D: Albendazole

A

A: Febantel

119
Q

What is characteristic to the mechanism of action of benzimidazoles?

A: None of them
B: Agonism of the nicotinic acetylcholine receptor
C: Reversible inhibition of the acetylcholinesterase
D: Both of them

A

A: None of them

120
Q

How does humidity affect the toxicity of diazinon?

A: Increases
B: Decreases
C: Dosent affect
D: Depending on the level of humidity, it can increase or decrease

A

A: Increases

121
Q

Wich statement is true? Usage of ectoparasiticide agents is inevitable because.

A:consequential anaemia due to blood sucking
B: Both of them
C: Ectoparasite can cause lesion, tissue damage
D: None of them

A

B: Both of them

122
Q

Which substance is an organophosphate from the following?

A: Both of them
B: Diazinon
C: Coumaphos
D: None of them

A

A: Both of them

123
Q

Praziquantel can NOT be used against the following helminth:

A: Dipylidium caninum
B: Fasciola hepatica
C: Both of them
D: None of them

A

?

124
Q

Which substance is an organophosphate from the following?

A: None of them
B: Flumethrin
C: Both of them
D: Amitraz

A

A: None of them

125
Q 
How are organophosphates eliminated? 
A: Mostly with bile
B: Mostly with urine
C: Mostly with sweat
D: Mostly with saliva and exhalation
A

B: Mostly with urine

126
Q

Which dog breed is sensitive to amitraz?

A: Kuvasz
B: Bobtail
C: Chihuahua
D: Yorkshire terrier

A

C: Chihuahua

127
Q

Which species is the most sensitive to organophosphates?

A: Sheep
B: Cat
C: Dog
D: Cattle

A

B: Cat

128
Q

Which agent has activity against fleas?

A: Fipronil
B: Pyriprole
C: None of them
D: Both of them

A

D: Both of them

129
Q

Which is true for amitraz?

A: In case if poisoning, alpha 2 receptor related symptoms occur
B: Both of them
C: Increased catecholamine effect elevates energy need of the parasites
D: None of the

A

B: Both of them

130
Q

What is characteristic to the mechanism of action of permethrin?

A: GABA receptor agonism
B: Na channel opening
C: Acetylcholine receptor antagonism
D: Acetylcholinesterase inhibition

A

B: Na channel opening

131
Q

Which macrocyclic lactone is effective against demodicosis?

A: Selamectin
B: Amitraz 2
C: Both of them
D: None of them

A

D: None of them

132
Q

Which is eliminated with the urine as well?

A: Fluralaner
B: Afoxolaner
C: Sarolaner
D: Lotilane

A

B: Afoxolaner

133
Q

Izoxasolines can be given..

A: None of them
B: Collar
C: Injection
D: Both of them

A

A: None of them

134
Q

Neonicotinoids are available in this form.

A: Collar
B: Injection
C: Both of them
D: None of them

A

D: None of them

135
Q

Which agent does NOT have adulticide effect from the following?

A: None of them
B: Methoprene
C: Lufenuron
D: Both have adulticide effects

A

A: None of them

136
Q

Sarolaner is effective against..

A: Scabies mite
B: Both of them
C: Tick
D: None of them

A

C: Tick

137
Q

This mechanism leads to the selective toxicity of ectoparasiticide agents:

A: Slower metabolism in the parasite
B: Good distribution through special barriers
C: Both of them
D: None of them

A

D: None of them

138
Q

What is characteristic to the pharmacokinetics of praziquantel ?

A: Not absorbed from the skin
B: Hydroxy metabolites form quickly
C: Moderate distribution due to high protein binding
D: None of them

A

D: None of them

139
Q

How can coumaphos be neutralised if it gets on the skin?

A: With baking soda
B: With tap water
C: With acetic acid
D: With all of them

A

A: With baking soda

140
Q

What is chacteristic to the spectrum of febantel?

A: Antitrematodal effect
B: Antinematodal effect
C: Both of them
D: None of them

A

B: Antinematodal effect

141
Q

What is characteristic to the spectrum of oxibendazole?

A: Anticestodal effect
B: Antinematodal effect
C: Both of them
D: None of them

A

C: Both of them

142
Q

How can albendazole be given?

A: Via injection
B: Both of them
C: Orally
D: None of them

A

C: Orally

143
Q

What is characteristic to the mechanism of action of benzimidazoles?

A: Both of them
B: Tegumentum damage
C: Decreased ATP production
D: None of them

A

A: Both of them

144
Q

Which agent is the safest for the environment from the following?

A: Indoxacarb
B: Imidacloprid
C: Fipronil
D:Permethrin

A

A: Indoxacarb

145
Q

How can fipronil be used in companion animals?

A: Spot on
B: Spray
C: None of them
D: Both of them

A

D: Both of them

146
Q

Izoxasolines are authorised for..

A: Horse
B: Cats
C: Both of them
D None of them

A

B: Cats

147
Q 
Which agent is a prodrug from the following? 
A: None of them
B: Triclabendazole
C: Fenbendazole
D: Both of them
A

A: None of them

148
Q

Levamisole can be used against the following helminth:

A: Ascarls suum
B: Fasciola hepatica
C: Dipylidium caninum
D: All of them

A

A: Ascarls suum

149
Q

What is the mechanism of action of indoxacarb?

A: Na channel blocking
B: Glutamate mediated Cl channel opening
C: GABA receptor antagonism
D: Acetylcholinesterase inhibition

A

A: Na channel blocking

150
Q

What is the mechanism of action of fipronil?

A: Acetylcholine receptor agonism
B: Acetylcholinesterase inhibition
C: GABA receptor agonism
D: GABA receptor antagonism

A

D: GABA receptor antagonism

151
Q

Permethrin is effective against this parasite:

A: Demodex spp
B: Tick
C: Both of them
D: None of them

A

B: Tick

152
Q

Which is the most effective agent from the following?

A: Afoxolaner
C: Sarolaner
B: Fluralaner
D: Their efficacy is similar

A

C: Sarolaner

153
Q

What does repellent effect mean?

A: Killing parasite
B: Attracting parasite
C: Keeping parasite away
D: Inhibiting the development of parasites

A

C: Keeping parasite away

154
Q

How can levamisole be given?

A: Orally an
B: Both of them
C: In pour on cattle
D: None of them

A

B: Both of them

155
Q

What is characteristic to the mechanism of action of isoquinolines?

A: Reversible inhibition of the acetylcholinesterase
B: Calcium metabolism damage and consequential
C: spastic paralysis
D: GABA receptor agonism

A

B: Calcium metabolism damage and consequential

156
Q

Which agent is effective against Dermanyssus gallinae?

A: Pyriproxyfen
B: Fluralaner
C: Flumethrin
D: All of them

A

B: Fluralaner

157
Q

What is characteristic to the spectrum of fenbendazole?

A: Anticestoral effect
B: Both of them
C: Antinematodal effect
D: None of them

A

B: Both of them

158
Q

Which agent is a prodrug from the following?

A: Both of them
B: Febantel
C: Netobimin
D: None of them

A

A: Both of them

159
Q

What is characteristic to the mechanism of action of macrocyclic lactones?

A: Cholinergic effect
B: Calcium channel damage and consequential spastic paralysis
C: Tegumentum damage
D: Opening the glutamate-mediated chloride ion channels

A

D: Opening the glutamate-mediated chloride ion channels

160
Q

Which is true for organophosphates?

A: LD50 oral > LD50 dermal
B: LD50oral < LD50 dermal
C: LD50 oral
D: LD50 dermal

A

B: LD50oral < LD50 dermal

161
Q

What is characteristic to the mechanism of action of benzimidazoles?

A: Damage of the endoplasmic reticulum and the mitochondrium
B: Cholinergic effect
C: Both of them
D: None of them

A

A: Damage of the endoplasmic reticulum and the mitochondrium

162
Q

Levamisole can be used against the following helminth:

A: Dictyocaulus viviparus (lungworm)
B: Anoplocephala perfoliata
C: Fasciola hepatica
D: All of them

A

A: Dictyocaulus viviparus (lungworm)

163
Q

Which species is sensitive to amitraz?

A: Dog
B: Both of them
C: Horse
D: None of them

A

C: Horse

164
Q

Which macrocyclic lactone is effective against scabies?

A: Amitraz
B: Both of them
C: None of them
D: Milbemycin oxime

A

C: None of them

165
Q

What is characteristic to the pharmacokinetics of praziquantel?

A: Elimination only in uncharged form
B: Quick and good absorption if given orally
C: Cumulations in fatty tissues due to lipophilic structure
D: None of them

A

B: Quick and good absorption if given orally

166
Q

What is characteristic to the mechanism of action of macrocyclic lactones?

A: GABA receptor agonism
B: Mitochondrium damage
C: Agonism of the nicotinic acetylcholine receptor
D: None of them

A

A: GABA receptor agonism

167
Q

Which of the following agents is an endectocide?

A: Imidacloprid
B: Both of them
C: None of them
D: Moxidectin

A

D: Moxidectin

168
Q

Praziquantel can be used against the following helminth:

A: Ascaris suum
B: Anoplocephala perfoliate
C: Both of them
D: None of them

A

D: None of them

169
Q

Repellent effect is important against this arthropod:

A: Demodex spp
B: Both of them
C: Fly
D: None of them

A

?

170
Q

What is characteristic to the mechanism of action of amitraz?

A: Monoamine oxidase inhibition
B: Alpha 2 receptor agonist
C: Both of them
D: None of them

A

C: Both of them

171
Q

Which can be an antidote of pyrethroid poisoning?

A: Pralidoxime
B: Atipamezole
C: None of them
D: Both of them

A

C: None of them

172
Q

Which agents can cause hyperpolarization in the parasite?

A: Moxidectin
B: Imidacloprid
C: Both of them
D: None of them

A

A: Moxidectin

173
Q

Which of the the following agent is an endectocide?

A: Permethrin
B: Toltrazuril
C: Levamisole
D: none of them

A

D: none of them

174
Q

Levamisole toxicosis can cause the following symptoms

A: Sympathetic signs
B: Parasympathetic signs
C: Severe kidney damage
D: Flaccid paralysis

A

B: Parasympathetic signs

175
Q

Praziquantel can NOT be used against the following helminth:

A: Dipylidium caninum
B: Fasciola hepatica
C: Both of them
D: None of them

A

B: Fasciola hepatica

Pharma 2 (2 decks)

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