MIDTERM Flashcards

1
Q

Define

What is epidemiology?

Lecture 1

A

the study of the distribution and determinants of health-related states or events among specific populations and the application of the study to the control of health problems

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2
Q

Epidemiology: True or False

Epidemiology is often described as the basic science of public health.

A

True

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3
Q

Epidemiology

What is distribution?

Lecture 1

A

frequency + pattern

  • in other words: “how many people?” + “where?”
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4
Q

Epidemiology: Distribution

Define frequency

Lecture 1

A
  • the number of health-related events
  • how often these events occur compared to the total number of people in the population
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5
Q

Epidemiology: Distribution

Define pattern

Lecture 1

A
  • occurrence of health-related events by time, place, and person
  • time may be: annual, seasonal, weekly, daily, hourly, weekday vs weekend, etc.
  • place includes: geographic variation, urban/rural differences, location of work sites or schools
  • personal characteristics include: age, sex, marital status, SES, behaviors, and environmental exposures
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6
Q

Epidemiology

What are determinants?

Lecture 1

A

the causes and other factors that influence the occurrence of disease and other health-related events

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7
Q

Specified Populations

Epidemiologist vs. Physicians

Lecture 1

A

Epidemiologist:
- concerned about the health of the overall population

Physicians:
- concerned about the health of an individual

clinician’s patient is indiviual; epidemiologist’s patient is community

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8
Q

Epidemiology

What is the application of epidemiology?

Lecture 1

A

it involves applying the knowledge gained by the studies to community-based practice b/c the goal is to prevent disease in the community

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9
Q

John Snow

Who is John Snow?

Lecture 2

A

An anesthesiologist in the mid 1800s who conducted a series of investigations in London.
- conducted studies of cholera outbreak to discover the cause of disease and how to prevent its recurrence

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10
Q

John Snow: True or False

The father of epidemiology is John Graunt.

Lecture 2

A

False

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11
Q

John Snow

Breakdown and explain Snow’s first investigation

Broad Sreet Pump

Lecture 2

A
  1. A severe cholera epidemic occurred / outbreak
  2. Snow created a spot map, marking where cholera cases occurred and the locations of water pumps
  3. He observed patterns and noticed most cases clustered around the Broad Street pump (Pump A)
  4. Then, he gathered community insights and found out that residents avoided Pump B because it was contaminated and Pump C because it was inconvenient
  5. To confirm his findings, he investigated anomalies and found that workers at a nearby brewery who drank from a private well did not get cholera and gathered infromation on where people with cholera obtained their water
  6. Snow formed his hypothesis and conclued that contaminated water from the Broad Street pump was likely the source of the outbreak
  7. Lastly, he took action by presenting his information to officials and got the pump handle removed
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12
Q

Epidemiology - John Snow

What is descriptive epidemiology?

Lecture 2

A

describing a health related event in terms of person, place, and time

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13
Q

Epidemiology - John Snow

What is analytic epidemiology?

Lecture 2

A

measures the association between an exposure and disease

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14
Q

John Snow

What does Snow’s research demonstrate

Lecture 2

A
  • descriptive epidemiology
  • hypothesis generation
  • hypothesis testing / analytical epidemiology
  • application
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15
Q

Epidemiology: Uses

What are the 4 diff uses of epidemiology?

Lecture 2

A
  1. Assessing the community’s health
  2. Making individual decisions
  3. Completing the clinical picture
  4. Searching for causes
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16
Q

Epidemiology: Uses

Assessing the community’s health

Explain

Lecture 2

A

use of data to set goals and monitor progress towards them
- need relevant sources of data

ex: Healthy People 2030

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17
Q

Epidemiology: Uses

Making individual decisions

Explain

Lecture 2

A

use of epidemiologic information to make daily decisions about health

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18
Q

Epidemiology: Uses

Completing the clinical picture

Explain

Lecture 2

A

epidemiologists assist physicians in properly diagnosing illness

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19
Q

Epidemiology: Uses

Searching for causes

Explain

Lecture 2

A

provides substantial evidence to link exposure and illness and effect action

in other words: why did this disease happen

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20
Q

Epidemiology: Core Functions

What are the 6 core functions of epidemiology?

Explain

Lecture 2

A
  1. public health surveillance
  2. field investigations
  3. analytic studies
  4. evaluation
  5. linkages
  6. policy development
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21
Q

Epidemiology: Core Functions

Public health surveillance

Explain

Lecture 2

A

ongoing, systemic collection of data to guide decision making and action

goal: to portray patterns of disease to control spread and implement prevention measures

how: morbidity and mortality reports

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22
Q

Public Health Surveillance

What is the difference between active and passive surveillance?

A
  • active: surveillance is on public officials
  • passive: other entities report the data
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23
Q

Epidemiology: Core Functions

Field Investigation

Explain

Lecture 2

A

the process of collecting and analyzing data directly in affected areas to find the source and spread of a disease

also referred to as “shoe leather epidemiology”

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24
Q

Epidemiology: Core Functions

Analytic studies

Explain

Lecture 2

A

evaluate the credibility of a hypothesis generated from surveillance and field invetigation

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25
Q

Epidemiology: Core Functions

Evaluation

Explain

Lecture 2

A

determmine relevance, effectiveness, efficiency, and impact in relation to goals

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26
Q

Epidemiology: Core Functions

Linkages

Explain

Lecture 2

A

connecting public health agencies, laboratories, and healthcare providers to share information and collaborate on disease prevention and response, etc.

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27
Q

Epidemiology: Core Functions

Policy Development

Explain

Lecture 2

A

creating and implementing public health policies based on data and research to protect and improve community health

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28
Q

Epidemiologic Approach

What does an epidemiologist do?

Lecture 3

A
  • Counts cases or health events, and describes them in terms of time, place, and person
  • Divides the number of cases by an appropiate denominator to calculate rates
  • Compares these rates over time or for different groups of people
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29
Q

Epidemiologic Approach

Define rate

Lecture 3

A

the number of cases divided by the size of the population per unit of time

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30
Q

Case definition

What is a case definition?

Lecture 3

A

a set of standard criteria for classifying whether a person has a particular disease, syndrome or other health condition

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31
Q

Case definition

What are the components of a case defintion?

Lecture 3

A
  • lab tests
  • signs (objective)
  • symptoms
  • time, place, and/or person (outbreak investigations)
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32
Q

True or False

Case definitions are set and do not change.

Lecture 3

A

False

case definitions may change over time as more information is obtained

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33
Q

Case definition

What are the different types of case definitions?

Lecture 3

A

sensitive: broad or loose
goal = to capture all true cases

strict: specific
goal = ensure an individual is truly a case

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34
Q

True or False

ALL case definitions require laboratory confirmation

Lecture 3

A

False

some disease have no distinctive laboratory findings

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35
Q

Epidemiology

What are the 5 W’s of epidemiology?

Lecture 3

A
  • what (health issue of concern)
  • who (person)
  • where (place)
  • when (time)
  • why/how (why is this disease occurring and how is it spreading)
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36
Q

Epidemiology

What are the different ways to compile data by time?

Lecture 3

A
  • secular trends (overtime/long term)
  • seasonally
  • days of the week/time of the day
  • epidemic period
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37
Q

Epidemiology

What are the different ways to compile data by geographic extent?

Lecture 3

A

unit:
- large (continent)
- small (hospital wing)

categorical:
- urban
- rural

state

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38
Q

Epidemiology

What is used to compile data when it comes to people?

Lecture 3

A
  • sex
  • ethnicity
  • SES
  • age
  • occupation
  • leisure activity
  • behaviors
  • use of medication
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39
Q

Epidemiology

What is the most important person attribute when compiling data according to the textbook?

Lecture 3

A

age

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40
Q

Analytic Epidemiology

What is the key feature of analytic epidemiology?

Lecture 3

A

comparison group

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41
Q

Analytic Epidemiology

What are the two categories of studies that fall under analytic epidemiology?

Lecture 3

A
  • experimental
  • observational
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42
Q

Analytic Epidemiology

What are the functions of an experimental study?

Lecture 3

A
  • controlled process determines the exposure for participants
  • tracking over time determines the effects of the exposure

ex: placebo

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43
Q

Analytic Epidemiology

What is the function of observational studies?

Lecture 3

A

to observe the exposure or disease status in participants

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44
Q

Analytic Epidemiology: Observational Studies

What are the 3 types of observational studies?

Lecture 3

A
  • cohort (prospective)
  • case control
  • cross sectional
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45
Q

Analytic Epidemiology

What are the features of a cohort study?

Lecture 3

A
  • start with exposed individuals (we know the exposure)
  • follow individual to see if they develop disease of interest
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46
Q

Analytic Epidemiology

What are the features of a case-control study?

Lecture 3

A
  • investigators enroll a group of participants with a disease (case-patients)
  • starts with ill individuals (we are looking for the exposure)
  • control group provides an estimate of the baseline or expected amount of exposure in the population
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47
Q

Analytic Epidemiology

What are the features of a cross-sectional study?

Lecture 3

A
  • weakest study because it lacks time aspect but gets a quick idea
  • exposures and health statuses of sample population are measured simultaneously
  • assesses the prevelance of a health outcome at that point in time without regard to duration
  • exposure and outcome are measured at the same time
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48
Q

Analytic Epidemiology

Overall summary

lecture 3

A

cohort: starts with exposed individuals

case control: starts with ill individuals (back tracking and seeing what exposure led to them being sick)

cross section: measures exposure and disease at the same time

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49
Q

Models of Disease Causation

What are the 3 models of disease causation discussed?

lecture 4

A
  • Rothman’s Pie
  • Chain of Infection
  • Epidemiologic Triad/Triangle (simplest)
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50
Q

Models of Disease Causation

What does the Epidemiologic Triad consist of?

lecture 4

A

agent, host, environment

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51
Q

Concepts of Disease Occurrence

Agent

lecture 4

A

infectious microorganism or pathogen
- virus, bacterium, parasite, or other microbe
- chemical contaminants or physical causes of disease or injury

generally: agent must be present for disease to occur

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52
Q

Concepts of Disease Occurrence

Host

lecture 4

A

the human who can get the diease
- dependent upon susceptibility, response to an agent

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53
Q

Concepts of Disease Occurrence

Environment

lecture 4

A

extrinsic factors that affect the agent and the opportunity for exposure

  • geology
  • climate
  • insects transmitting the agent
  • socioeconmic factors
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54
Q

Models of Disease Causation

Rothman’s Pie

lecture 4

A

all pieces of the pie fall into place = disease occurs

  • component causes: individual factors (one piece)
  • sufficient causes: complete pie (if more pieces come together
  • necessary causes: component that occurs in every disease pie (most usually its the bacteria)
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55
Q

Concepts of Disease Occurrence

Natural history

define

lecture 4

A

the progression of disease in an individual over time in the absence of treatment

timeline could be years

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56
Q

Concepts of Disease Occurrence

Spectrum of disease

define

lecture 4

A

the range of manifestations and severities of illness associated with given dieases, illness or injury

57
Q

Infectious Agents

What are the terms for infectious agents?

lecture 4

A

infectivity: proportion of exposed persons who become infected

pathogenicity: proportion of infected individuals who develop clincally apparent disease

virulence: the proportion of clinically apparent cases that are severe or fatal

58
Q

Natural History Timeline

What is the timeline for disease?

lecture 4

A
  1. stage of susceptibility (exposure occurs)
  2. stage of subclinical disease (where pathologic changes occur but individual does not know they are sick; asymptomatic)
    in between: onset of symptoms and usual time of diagnosis
  3. stage of clinical disease (symptoms present and individual knows they are sick)
  4. stage of recovery, disability or death

infectious disease: incubation period
chronic disease: latency period

59
Q

Chain of infection

What is the chain of transmission?

lecture 4

A

transmission occurs when the agent leaves its reservoir or host through a portal of exit, is conveyed by some mode of transmission and enters through a portal of entry to infect a susceptible host

60
Q

Portal of Exit

What is portal of exit?

lecture 4

A

how the pathogen leaves its host

corresponds to the site where the pathogen is localized

61
Q

Modes of Transmission

What are the two modes of transmission?

define

lecture 4

A

direct:
- direct contact (mono)
- droplet spread (sneezing, coughing, etc.)

indirect:
- airbone (infectious agents carried by dust or droplet nuclei suspended in the air; ex: measles)
- vehicle (food, water, biologic products)
- vector (mosquitoes, fleas, ticks, etc.)

62
Q

Modes of Transmission

Define airbone

lecture 4

A

infectious agents carried by dust or droplet nuclei suspended in the air

63
Q

Modes of Transmission

Define vehicle

lecture 4

A

food, water, biologic products (blood), etc

64
Q

Modes of Transmission

Define vector

lecture 4

A

mosquitoes, fleas, ticks, etc.

65
Q

Portal of Entry

What is portal of entry?

lecture 4

A

how a pathogen enters a susceptible host

ex: skin, mucous membrane, blood

66
Q

Disease Control - Chain of Infection

How do we eliminate the agent?

EXAMPLE

lecture 4

A

antibiotics

67
Q

Disease Control - Chain of Infection

What methods can help to control the mode of transmission of a disease?

EXAMPLE

lecture 4

A
  • isolation/quarantine
  • elimination of the vehicle
68
Q

Disease Control - Chain of Infection

How can we protect portals of entry?

EXAMPLE

lecture 4

A
  • bed nets
  • masks, gloves
69
Q

Disease Control - Chain of Infection

How can we increase a host’s defense?

EXAMPLE

lecture 4

A

vaccination

70
Q

How does the host susceptibility vary?

lecture 4

A
  • genetics differ
  • immune/resistant to disease
  • lifestyle factors

etc.

71
Q

Implications for Public Health

What are interventions directed at?

lecture 4

A
  • controlling or eliminating agent
  • interrupting the mode of transmission
  • protecting portals of entry
  • increasing a host’s defenses
72
Q

Level of Disease

What levels of disease are there?

lecture 4

A
  • sporadic
  • endemic
  • hyperendemic
  • epidemic
  • outbreak
  • cluster
  • pandemic
73
Q

Level of Disease

Define sporadic

Lecture 4

A

disease that occurs infrequency/irregularly
- uncommon
- random
- one case/first case

74
Q

Level of Disease

Define endemic

Lecture 4

A

amount of disease usually present in a community
- typical cold or flu
- we expect this, its our usual

75
Q

Level of Disease

Define hyperendemic

Lecture 4

A

persistent, high levels of disease
- regularly

76
Q

Level of Disease

Define epidemic

Lecture 4

A

often sudden increase of cases

77
Q

Level of Disease

Define outbreak

Lecture 4

A

often sudden increase of cases in a more limited geographic location
- ex: on stony brook campus vs in state of NY

78
Q

Level of Disease

Define cluster

Lecture 4

A

aggregation of cases grouped in place and time suspected to be greated than the number expected
- don’t know why
- unrelated

79
Q

Level of Disease

Define pandemic

Lecture 4

A

epidemic spread over several countries or continents

80
Q

Levels of Disease - Epidemic

Why do epidemics occur?

lecture 4

A
  • agent and host present inadequate numbers
  • increase in amount of virulence of agent
  • introduction of agent in a setting it has never been before
  • enhanced mode of transmission
  • change in susceptibility of hosts
  • new portals of entry
81
Q

Epidemic Patterns

What are the type of patterns used to classify epidemics?

classified according to their manner of spread through a population

lecture 4

A
  • common source
  • propagated
  • mixed
82
Q

Epidemic Patterns

Define common source

lecture 4

A

group of persons are all exposed to an infectious agent or a toxin from the same source

point source: group exposed over a relatively brief period (becoming sick in the same incubation period)

continous common source: case-patients exposed over days, weeks, or longer

intermittent common source: irregular pattern of exposure (still from the same source)

83
Q

Epidemic Patterns

Define propagated

lecture 4

A

transmission from one person to another; cases occur over more than one incubation period
- direct person-to-person
- vehicle or vectorborne

84
Q

Organizing Data: Line Listing

What is line listing used for?

lecture 5

A

used in routine surveillance, investigating an outbreak, conducting a study, etc. to compile information in an organized manner

organized like a spreadsheet with rows and columns

85
Q

Organizing Data: Line Listing

What makes up a line listing?

lecture 5

A

row: called a record or observation
- represents one person or case of disease

column: called a variable
- contains information about one characteristic of the individuals (race or date of birth)

86
Q

Organizing Data: Line Listing

What is a value?

lecture 5

A

value of a variable is the number or descriptor that applies to a particular person (5’6”, female, never vaccinated, etc.)

  • the type of values influence the way in which the variables can be summarized

can be numeric but also can be descriptive + there are four types

87
Q

Organizing Data: Line Listing

What are the four types of variables?

lecture 5

A
  • nominal-scale variable
  • ordinal-scale variable
  • interval-scale variable
  • ratio-scale variable
88
Q

Organizing Data: Types of variables

nominal

define

lecture 5

A

values are categorized without numerical ranking

(ex: ill or well, dead or alive)

89
Q

Organizing Data: Types of variables

ordinal

define

lecture 5

A

values are ranked but not necessarily evenly spaced
(ex: stages of breast cancer)

90
Q

Organizing Data: Types of variables

interval

define

lecture 5

A

measured on a scale of equally spaced units but without a true zero point (ex: shoe sizes, test scores)

91
Q

Organizing Data: Types of variables

ratio

define

lecture 5

A

an interval variable with a true zero (ex: height, age, sickness duration)

92
Q

Organizing Data: Line Listing

Which variables of the 4 are qualitative variables?

also known as categorical

lecture 5

A

nominal and ordinal

93
Q

Organizing Data: Frequency Distribution

Which variables of the 4 are quantitative variables?

also known as continuous

lecture 5

A

interval and ratio

94
Q

Frequency Distributions

What is a frequency distribution?

lecture 5

A

a table or graph that shows how often different values or group of values appear in a dataset

in public health terms: a way of organizing and presenting health related data to show how often a particular health condition, behavior, or characteristic occurs in a population
- helps identify trends, risk factors, and disparities in health outcomes

95
Q

Frequency Distributions

What are the features/properties of frequency distributions?

lecture 5

A
  • central location
  • spread
  • shape
  • range
96
Q

Frequency Distributions

What is the Gaussian distribution?

also known as normal distribution

lecture 5

A

the classic symmetrical bell-shaped curve
- no skew

97
Q

spread

lecture 5

A

how widely dispersed a graph is

98
Q

shape

lecture 5

A

symmetry

can be symmetrical or asymmetrical (skewed)

99
Q

Shape: Skewness

positive skew

define

A

central location is to the left of the tail (tail points to the right)

100
Q

Shape: Skewness

negative skew

define

A

central location is to the right of the tail (tail points to the left)

101
Q

range

lecture 5

A

measured by spread and distribution

102
Q

Frequency Distributions: Properties

central location

define

lecture 5

A

where the graph peaks

there are three measures of central location used in epidemiology: mean, median, and mode

103
Q

Central Location: Types of Measures

mean

lecture 5

A

the average value (add up all the numbers and divide by the amount of numbers that are present)

use:
- has excellent statistical properties; commonly used in statistical manipulations and analyses
- called the center of gravity
- affected by any extreme value

104
Q

Central Location: Types of Measures

median

lecture 5

A

number in the middle (after being numerically ordered)

use:
- good descriptive measure
- relatively easy to identify
- not often used in statistical manipulations and analyses
- not generally affected by extreme values

105
Q

Central Location: Types of Measures

mode

lecture 5

A

number that shows up the most

use:
- preferred measure of central location
- can have one or two more
- used almost exclusively as a descriptive measure
- not affected by extreme values

106
Q

Investigating an Outbreak

Why would we investigate an outbreak?

lecture 6

A
  • control or prevention of the health problem
  • opportunity to learn / research
  • public, political, or legal concerns
  • public health program considerations
  • training

the most important reason is for control and prevention

107
Q

Investigating an Outbreak

What are the steps of an outbreak investigation?

lecture 6

A
  1. prepare for field work
  2. establish the existence of an outbreak
  3. verify the diagnosis
  4. contruct a working case definition
  5. find cases systemically and record information
  6. perform descriptive epidemiology
  7. develop hypotheses
  8. evaluate hypotheses epidemiologically
  9. reconsider, refine, re-evaluate
  10. compare with lab and/or environment studies
  11. implement control and prevention measures
  12. initiate or maintain surveillance
  13. communicate findings
108
Q

Investigating an Outbreak: Steps (1)

Prepare for field work

define

lecture 6

A

officials discover an increase in the number of cases of a particular disease and then decide that a field investigation is warranted

  • scientific and investigate issues: must have the appropiate scientific knowledge, supplies, and equipment
    • review applicable literature
    • assemble useful references (jounrnal articles, sample questionnares)
    • know what supplies/equipment to protect yourself
    • have a plan of action
  • management and operational issues: must be a good manager and collaborator because most investigations are conducted by a team rather than just one individual
    • roles and responsibilities for each members
    • communications plan to know how often and when to calls with involved agencies, etc.
    • arrange travel, lodging and local transportation
109
Q

Investigating an Outbreak: Steps (2)

Establish the existence of an outbreak

define

lecture 6

A

verify that the cases are in fact an outbreak; observed cases compared to the number of expected cases
- outbreak or an epidemic: the occurrence of more cases of disease than expected in a given area or among a specific group of people over a particular period of time

110
Q

Investigating an Outbreak: Steps (3)

Verify the diagnosis

define

lecture 6

A

important because you must ensure that the disease has been properly identified since control measures are often disease specific and to rule out laboratory error as the basis for the increase in reported cases
- review clinical findings and lab results
- visit one or more patients with the disease to get a better understanding of clinical features

Helps with generating a hypotheses about disease spread

just like John Snow did with his investigation

111
Q

Investigating an Outbreak: Steps (4)

Construct a working case defintion

define

lecture 6

A

includes clinical criteria, and may be restricted by time, place, and person
- diagnosis may be uncertain early on in an investigation. so, cases will be classified as suspected, probable, and confirmed

112
Q

Investigating an Outbreak: Steps (5)

Find cases & record information

define

lecture 6

A

public health workers must look for additional cases to determine the true geographic extent of the problem and the populations affected by it
- passive surveillance: sending a letter describing the situation and asking for reports of similar cases (other entities report the data)
- active surveillance: telephoning or visiting the facilities by self to collect information on any additional cases

following data is collected:
- identifying information
- demographic information
- clinical information
- risk factor information
- reporter information (source of the report)

113
Q

Investigating an Outbreak: Steps (6)

Perform descriptive epidemiology

define

lecture 6

A

summarizing by time, place, and person
- provides a comprehensive characterization of the outbreak
- infer the population at risk for disease
- provides clues about source, modes of transmission, etc.
- begin thinking about where to begin intervention

helps formulate hypotheses

114
Q

Investigating an Outbreak: Steps (7)

Develop hypotheses

define

lecture 6

A
  • if the epidemic curve points to a narrow period of exposure, what events occurred around that time?
  • why do these people living in one particular area have the highest rate of disease
  • why are some groups at greater risk than others?

answers to these questions assist epidemiogists in formulating their hypothesis

115
Q

Investigating an Outbreak: Steps (8)

Evaluate hypotheses

define

lecture 6

A

2 ways:
1. compare hypothesis to established facts
2. use analytic epidemiology to quantify relationships:
- retrospective cohort/risk ratio
- case-cohort/odds ratio

116
Q

Analytic Evaluation (Step 8)

What does a retrospective cohort study consist of?

lecture 6

A
  • small, well-defined population
  • exposure and outcomes have already occurred
  • calculate the attack rate for those exposed to those not exposed
  • calculate risk ratio
117
Q

Analytic Evaluation (Step 8)

How do you calculate the attack rate?

lecture 6

A

attack rate = those sick who were exposed/ALL exposed

attack rate = those sick who were not exposed/ALL unexposed

high attack rate among those exposed and low attack rate among those not exposed = exposure is a strong suspect

118
Q

Analytic Evaluation (Step 8)

What is the method for calculating risk ratio?

lecture 6

A

attack rate in exposed group/attack rate in unexposed group

119
Q

Analytic Evaluation (Step 8)

What does a case-cohort consist of?

lecture 6

A

investigator asks case-patients and controls about their exposures and conducts an odds ratio to quantify the relationship between exposure and disease

controls need to be identified in this study

120
Q

Analytic Evaluation (Step 8)

What is the method for calculating the odds ratio?

lecture 6

A

(number of exposed cases x number of unexposed controls) / (number of exposed controls x number of unexposed cases)

or

(AxD)/(BxC)

121
Q

Investigating an Outbreak: Steps (9)

Reconsider, refine, re-evaluate

define

lecture 6

A

done in the case that analytic studies do not provide adequate insight

122
Q

Investigating an Outbreak: Steps (10)

Compare - lab & environmental

define

lecture 6

A

laboratory evidence can confirm the findings

environmental studies can explain why an outbreak occurred

123
Q

Investigating an Outbreak: Steps (11)

Control & prevention

define

lecture 6

A

primary goal: to control outbreak AND prevent additional cases

control measure are usally aimed at segments of the chain of transmission (agent, host, mode of transmission, portal of entry)

124
Q

Investigating an Outbreak: Steps (12)

Initiate / maintain surveillance

define

lecture 6

A

once control and prevention measures are implemented, they must be monitored
- this usually comes in the form of active surveillance

questions epidemiologists ask:
- are new cases slowing down or stopping
- are new cases continuing to occur
- where are the new cases, if any
- has the outbreak spread outside the original area where interventions were targeted

125
Q

Investigating an Outbreak: Steps (13)

Communicate findings

define

lecture 6

A

oral briefing for local authorities
- in attendance: local health authorities, those responsible for implementing control and prevention measures (epidemiologists)
- investigator describes what they found and recommendations for action

written report
- the usual format (intro, background, methods, etc…)
- this may serve as a reference for health departments encountering a similar outbreak in the future

126
Q

Measures of RIsk

What is a frequency measure?

lecture 7

A

characterizes only one part of the distribution to another part of the distribution

consists of: ratios, proportions and rates

127
Q

Frequency Measures

What is a ratio?

lecture 7

A

a comparison of any two values

  • will always have a fraction
  • the numerator and denominator of a ratio can be related or unrelated
    ex: you can be comparing apples to oranges
128
Q

Frequency Measures

What is a proportion?

lecture 7

A

comparison of a part to the whole
- the numerator is included in the denominator

129
Q

Frequency Measures

What is a rate?

lecture 7

A

a measure of the frequency with which an event occurs in a defined population over a specified period of time

  • useful for comparing disease frequency in different locations, at different times or among different groups of people with potentially different sized populations
130
Q

Mortality Requency Measures

What is an infant mortality rate?

lecture 7

A

number of deaths among children less than one year old
- denominator = number of live births during the same time period
- most commonly used measure for comparing health status among nations

very telling of a how well a country’s population is doing

131
Q

Rates

Define incidence

lecture 7

A

occurence of new cases of disease in a population over a specified period of time

132
Q

Rates

What does incidence describe?

lecture 7

A
  • the probability of developing the disease during a specific period
  • describes how quickly a disease occurs in a population
133
Q

Define prevelance

lecture 7

A

proportion of persons in a population who have a particular disease or attribute at a specified point in time or over a specificed point in time
- measure used for chronic disease rate

134
Q

Examples

What is the following fraction an example of:

number of women who have breast cancer in NYS / number of women who have cervical cancer in NYS

lecture 7

135
Q

Examples

What is the following ratio an example of:

number of women who have breast cancer in NY / number of women who have any type of cancer in NY

lecture 7

A

proportion

136
Q

Examples

What is the following fraction an example of:

number of men who died from lung cancer in NYS in Feb 2025 / number of men living in NYS in Feb 2025

lecture 7

137
Q

Examples

What is the following fraction an example of:

number of deaths among children less than 1 year of age reported during a given time period x 1,000 / number of live births reported during the same time period

lecture 7

A

infant mortality rate

138
Q

Examples

What is the following fraction an example of:

number of women newly diagnosed with heart disease in NYS in 2025 / number of women living in NYS in 2025

lecture 7

A

incidence

key word: newly

139
Q

Examples

What is the following an example of:

number of women who have breast cancer in NYS / number of women living in NYS

lecture 7

A

prevelance

numerator incl. all cases present during given time period NOT JUST NEW