Midterm 1: Herpesvirus Flashcards
Herpesviruses are good antigens
False
Alphaherpesviruses are host specific slowly multiplying (24hrs) viruses
False
Alphaherpesviruses may cause latent infection in neurons or ganglia
True
Some herpesviruses have a broad host spectrum (euryxen)
True
Gammaherpesviruses may cause latent infection in neurons of ganglia
False (lymphoid cells, alpha = neurons)
Herpes viruses are resistant to detergents
False
Herpesviruses are sensitive to detergents
True
Herpesviruses are generally weak antigens
True
Herpesviruses can cause latent persistent infections
True
Herpesviruses are typically stenoxen viruses, but there are significant exceptions
True
Herpesviruses are strong antigens, therefore single vaccinations provide lifelong protection
False
Herpesviruses are enveloped viruses, therefore they are sensitive to detergents
True
There are no serological cross-reactions between different herpesvirus species
False
Because the genome of herpesviruses is very stable, no attenuated mutant vaccine strains are available
False
Infectious bovine vulvovaginitis virus strains cause abortions and foetal deformities
False
Herpesvirus infections frequently result in latent virus carry
True
Herpesviruses usually cause latent infections and life-long virus carries
True
Infectious bovine rhinotracheitis virus can cause abortion
True
The use of marker vaccines can help the eradication of infectious bovine rhinotracheitis virus
True
The most frequently used eradication strategy for IBRV is selection with the help of marker vaccines
True
Marker vaccines can be used in IBRV eradication programs in cattle farms
True
Antibodies against infectious bovine rhinotracheitis virus (IBRV) might be detected in the milk
True
Conjunctivitis and blepharitis are signs of infectious bovine rhinotracheitis
True
The infectious bovine rhinotracheitis virus (IBRV) causes haemorrhagic gastroenteritis
False
Infectious bovine rhinotracheitis virus also causes mastitis in cows
False
Infectious bovine rhinotracheitis virus is transmitted by arthropods
False
Infectious bovine rhinotracheitis virus can cause fatal encephalitis in calves
True
Infectious Bovine Rhinotracheitis virus frequently causes encephalitis in old cow and bulls
False
Infectious Bovine Rhinotracheitis virus frequently causes encephalitis in old sow and bulls
False
Infectious Bovine Rhinotracheitis can be endemic on cattle farms
True
Infectious bovine rhinotracheitis virus can cause skin lesions on the genitals
True
Bulls can shed the infectious bovine rhinotracheitis with semen
True
The infectious bovine rhinotracheitis virus (IBRV) may spread via semen
True
Pregnant cows should be immunised with inactivated vaccines against IBRV
True
Pregnant cows should be immunised against IBRV only with inactivated vaccines
True
Attenuated vaccines are used in pregnant cows against Infectious Bovine Rhinotracheitis virus
False
Pregnant cows can be immunised against IBRV only with attenuated vaccines
False
Because Bovine herpesvirus l causes latent infections; it is not possible to eradicate it from a cattle population
False
Bovine herpesvirus l may cause encephalitis in calves
True
IBRV may cause encephalitis in calves
True
Only inactivated vaccines are available against Bovine herpesvirus l
False
Bovine herpesvirus 1 may be transmitted through semen
True
Seropositive cattle cannot be carriers of the Infections Rhinotracheitis virus
False
Infectious Bovine Rhinotracheitis virus (IBRV) can be transmitted through vectors
False
The IBR virus causes nephritis in calves usually in the age between one and six months
False
Infectious Bovine Rhinotracheitis (IBR) causes serous nasal discharge
True (starts off as serous, then becomes mucopurulent)
Infectious Bovine Rhinotracheitis in 6-month-old calves usually causes pneumonia
True (?)
Infectious Bovine Rhinotracheitis in cattle 6 months of age can cause encephalitis
False
Infectious Bovine Rhinotracheitis often causes genital lesions with vesicles
True
Infectious Bovine Rhinotracheitis may cause inflammation of conjunctiva
True
Infectious Bovine Rhinotracheitis causes purulent discharge
True
In Hungary the IgE-negative marker vaccine is to be used in the control of Infectious Bovine Rhinotracheitis
True
Infectious Bovine Rhinotracheitis is rapidly spread within the herd
False
Infectious Bovine Rhinotracheitis is no longer present in Hungary
False
The respiratory form of Infectious Bovine Rhinotracheitis is often followed by genital symptoms
False
Infectious Bovine Rhinotracheitis spreads slowly within a herd
True
We can see characteristic clinical signs of Infectious Bovine Rhinotracheitis in day-old calves
False
We are doing Infectious Bovine Rhinotracheitis virus eradication programs in Hungary
True
Infectious Bovine Rhinotracheitis virus mainly causes encephalitis in cattle older than 6 months
False
Infectious Bovine Rhinotracheitis mainly causes pneumonia in 1-6 months old calves
True
Infectious Bovine Rhinotracheitis is rare, BHV-1 only affects cattle
False
In the transmission IBRV, the most important route is the germinative route
False
Genital form of IBR is often followed by abortion
False
IBR can occur in several clinical forms
True
IBR is a frequent infection, cattle and its closest relatives are affected
True
Bovine Herpes virus 2 frequently causes abortion
False
Bovine herpes mammillitis virus can cause mastitis in cows
True (doesn’t cause it but can predispose it)
Bovine herpes mammillitis virus may cause lesions on the muzzle of suckling calves
True
The bovine herpes mammillitis virus causes lesions on the skin of the milkers, therefore it is a zoonotic agent
False
Bovine herpesvirus 2 may cause generalised skin lesions
True
Bovine herpesvirus 2 is the most frequent primary cause of mastitis in cattle
False
Bovine Herpes Mammillitis virus causes milkers nodules in humans
False
Bovine Herpes Mammillitis virus may cause lesions on the lips of milking calves
True
Regarding Bovine Herpes Mammillitis, mainly heifers show clinical signs
True
Swine inclusion body rhinitis virus is causing mainly subclinical infection
True
Bloody nasal discharge can be a sign of swine inclusion body rhinitis
True
Clinical manifestation of swine inclusion body rhinitis is usually seen in piglets less than 3 weeks old
True
Inclusion body rhinitis is predisposing to fatal respiratory disease in pigs
False
Suid herpesvirus 2 may cause upper respiratory tract disease in piglets
True
Swine Inclusion Body Rhinitis is usually seen in piglets
True
The Swine Inclusion Body Rhinitis virus may cause reproductive problems in sows
True
Malignant catarrhal fever is mostly fatal in sheep
False
Malignant catarrhal fever is an alphaherpesvirus causing latent infection in ganglia
False
Malignant catarrhal fever develops only in suckling calves up to two weeks of age
False
Malignant catarrhal fever can be seen only in calves younger than one month
False
Malignant catarrhal fever causes only mild respiratory disease in sheep
False
Sheep should be immunised against malignant catarrhal fever virus
False
Malignant catarrhal fever may develop in swine too
True
Malignant catarrhal fever is frequently seen in cats
False
Cattle should be vaccinated against malignant catarrhal fever
False
Goats are the reservoir hosts of the malignant catarrhal fever virus
False
The incubation period of malignant catarrhal fever is less than one week
False
Malignant catarrhal fever is quickly spreading from cattle to cattle
False
Cattle should be vaccinated against malignant catarrhal fever every six months
False
The malignant catarrhal fever is caused by Bovine Herpes virus-2
False
Malignant Catarrhal Fever is usually lethal in cattle
True
Rodents are the reservoir hosts of the Malignant Catarrhal Fever virus
False
Swine are the reservoir host of the Malignant Catarrhal Fever virus
False
The Malignant Catarrhal Fever is caused by Bovine herpesvirus-2
False
We vaccinate calves 2 times against Malignant Catarrhal Fever
False
Swine are affected by Malignant Catarrhal Fever
True
Malignant Catarrhal Fever does not occur in Europe
False
Malignant Catarrhal Fever can cause diarrhoea
True
Malignant Catarrhal Fever spreads slowly within a cattle herd
False
Malignant Catarrhal Fever occurs if we keep cattle and sheep together
True
Malignant Catarrhal Fever does not occur in Hungary
False
Equine rhinopneumonitis virus is transmitted by arthropods
False
For immunisation against equine rhinopneumonitis virus mostly marker vaccines are used
False
Equine rhinopneumonitis virus can cause abortion several weeks after acute infection
True
Equine rhinopneumonitis virus causes cytoplasmic inclusion bodies in the foetal hepatocytes
False
Equid herpesvirus 4 more frequently causes encephalitis than Equid herpesvirus 1
False
Horses should be vaccinated against equine rhinopneumonitis virus at least every 6 months
True
Equine rhinopneumonitis virus causes necrotic foci in the liver of the foetus
True
Fever and serous nasal discharge are early signs of acute equine rhinopneumonitis
True
Equine rhinopneumonitis virus can cause purulent metritis
False
Only equine herpesvirus 4 can cause abortion
False
Pregnant mares abort usually in the acute phase of equine rhinopneumonitis
False
After EHV1 infection pregnant mares abort in the acute febrile stage
False
Immunisation against equine rhinopneumonitis virus provides life long protection
False
Equine rhinopneumonitis virus is present only in North America
False
The equid herpesvirus 1 may cause abortion storms in studs
True
Pregnant mares abort usually several weeks after equid herpesvirus 1 infection
True
Vaccinated horses cannot get infected with Equid herpesvirus 1
False
Equid herpesvirus 1 associated abortions are always sporadic
False
Equid herpesvirus 1 may cause subclinical infection in horses
True
Only pregnant mares should be immunised against Equid herpesvirus-1 infection
False
A single vaccination against Equid herpesvirus-1 provides life-long protection
False
Equine rhinopneumonitis virus can cause only respiratory problems
False
Both equid herpesvirus 1 and 4 can cause abortion
True
For immunisation against Equine rhinopneumonitis virus mostly marker vaccines are used
False
A single vaccination of a horse against EHV-1 induces protection for several years
False
Equine herpesvirus-4 primarily causes abortion in horses
False
Equine herpesvirus-4 causes mainly respiratory symptoms in horses
True
Equine herpesvirus-1 contains cross-reactive proteins against disease caused by EHV-4
True
Vaccination containing Equine herpesvirus-1 also provides protection against EHV-4
True
Equine herpesvirus-1 primarily causes respiratory symptoms in horses
True
Equine herpesvirus-1 primarily causes abortion
False
One vaccination is enough to prevent Equine herpesvirus-1
False
Mares infected with Equine herpesvirus-1 have a febrile state, then abort
True
Horses should be vaccinated against Equine herpesvirus-1 every six months
False
Equine herpesvirus 2 may cause keratoconjunctivitis
True
Equine herpesvirus 2 can cause respiratory disease only in young foals
True
Equid herpesvirus-2 may cause respiratory disease in foals
True
Equid herpesvirus 5 may play a role in the equine multinodular pulmonary fibrosis
True
Equid herpesvirus 2 may cause keratoconjunctivitis in foals
True
Equid herpesvirus 5 causes encephalitis in foals
False
Equine herpesvirus-2 and 5 causes pustular vulvovaginitis
False
Equid herpesvirus-2 may cause Coital Exanthemas in horses
False
Equid herpesvirus-2 and 5 cause diarrhoea and hepatitis in foals
False
In horses infected with Equine herpesvirus-2, the symptoms are often unnoticed
True
Equine herpesvirus-2 in horses does not cause symptoms in adult animals
True
It is enough to vaccinate mares 2 times against Equine herpesvirus-2
False
Equid herpesvirus 3 can cause lesions on the genital mucosa without abortion
True
Equid herpesvirus 3 may cause coital exanthema in horses
True