Midterm 1 Flashcards

1
Q

What is a non communicable disease?

A

often chronic, result of combination of genetic, physiological, environmental and behavioral factors

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2
Q

What are the 4 main kinds of NCDs?

A
  • Cardiovascular diseases
  • Cancers
  • Chronic respiratory diseases
  • metabolic diseases (diabetes)
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3
Q

What is the leading cause of death in Canada?

A

Cancer

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4
Q

Why are NCDs rising in lowand mid income countries?

A
  • treatment can drain household resources

- private healthcare

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5
Q

What are 6 modifiable risk factors?

A
  • obeisity
  • high BP
  • smoking
  • diabetes
  • psychosocial facotrs
  • high cholesterol
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6
Q

what are 4 non-modifiable risk factors?

A
  • genetics
  • gender
  • age
  • ethnicity
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7
Q

what are 4 main modifiable risk factors most associated with NCDs?

A
  • Tobacco use
  • diet
  • physical inactivity
  • harmful use of alcohol
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8
Q

What is the role of the cardiovascular system?

A

transports nutrients and oxygen to cells in body while CO2 and waste products of cell metablism are removed

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9
Q

Which blood vessels carry blood away from heart?

A

Arteries

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10
Q

where is nutrients exchanged in blood path?

A

capillaries

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11
Q

the top chambers of the heart are the

A

atriums

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12
Q

blood enters right atrium via

A

superior and inferior venae cavae

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13
Q

blood enters right ventricle via

A

tricuspid valve

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14
Q

blood is ejected from right ventricle via the

A

pulmonary artery

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15
Q

blood enters left atrium via

A

pulmonary veins

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16
Q

blood enters left ventricle via

A

bicuspic/mitral valve

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17
Q

blood is ejected from left ventricle via

A

aorta

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18
Q

where does blood go from aorta

A

coronary arteries

body

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19
Q

which ventricle is thicker and why?

A

left ventricle is thicker because it needs to push against greater resistance

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20
Q

are atriums or ventricles thicker. why?

A

ventricles are thicker and stronger because they need to push harder

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21
Q

where are the semilunar valves located

A

lead to aorta and pulmonary artery

22
Q

what did the framingham study find?

A

CVD is multi factorial

23
Q

what were thefindings of the monica project?

A

coronary hard disease is decreasing because of reduced smoking, hypertension rates, but obeisity is going back up

24
Q

what are the 4 main modifiable risk factors for CHD

A

-cigarette
-hypertension
elevated cholesterol
-diabetes

25
what is the clinical definition of blood pressure
systolic of 140 and diastolic of 90
26
blood pressure is dependent upon:
- cardiac output - total blood volume - viscocity - resistance
27
how does sodium intake increase blood pressure?
- salty diet - water retention increases blood volume - volume increases blood pressure
28
what is hypertension known as in pregnant women?
pre-eclampsia | can turn into eclampsia where protein develops in urine and seizures happen
29
what is the clinical presentation of HTN:
usually asymptomatic until complications occue. (heartdisease, kidney failure, retina malfunction)
30
what is tx for hypertension?
pharmacotherapy (diuretics, calcium channel blockers | lifestyle changes
31
what is prevention?
lifestyle changes
32
what is atherosclerosis
arterial wall hardening and loss of elasticity
33
how is atherosclerosis causes?
caused by atherosclerotic plaque build up in vessel wall
34
plaque has 3 main components:
- smooth uscle cells, macrophages and leukocytes - extracellular matrix - cholesterol particles (lipoproteins)
35
what is the first sign of athsclor
fatty streaks present in aorta almost from birth
36
what is the 4 step plaque building process?
- excess cholestrol in blood vessels collects in artery wall - body sends wbc - macrophage cells die after eating cholesterol - dead cells contribute to formation of plaque
37
What is acute coronary syndrome?
- unstable angina - myocardial infarction - sudden cardiac death
38
Chronic coronary artery disease
- stable angina | - coronary artery disease
39
What i s myocardial ischemia? what does it do?
imbalance between myocardial O supply n demand | impairs pumping ability of heart due to insuff O, reduced nutrient, inadequate removal of waste
40
what is angina pectoris
-chest pain caused by MI
41
What are the two types of angina?
Stable angina: common, due to narrowing of coronary artery Unstable angina: pain occurs at rest, due to rupture of plaque
42
What is sudden cardiac death?
unexpected death from cardiac causes, coronary atherosclerosis
43
What is a cardiac arrhythmia
disturbance of crdiac rhythm
44
What are the effects of nicotine on CHD?
- vasoconstrictor | - tobacco contains carcinogens
45
Preventio of CHD:
anticholest/hypertens/diabetic meds sodium restriction weight reduction
46
Definition of myocardial infarction:
interpution of blood supply to part of heart causing necrosis Infarct: ischemic necrosis of myocardium because cannot self repair
47
what is most common cause of heart attak:
occlusion of coronary artery caused by artherosclerosis or rupture of artherosclertic plaque
48
what are the 2 types of MI
subendocardial infarction: involves inner 1/3to 1/2 of ventricular wall transmural infarction: full thickness of ventricular wall
49
what is cardiogenic shock?
complications from MI, severe ventricular dysfunction
50
what is ventricular aneurysm?
patch of weakened tissue in ventricular wall