Midterm 1 Flashcards
The computational branch of molecular biology is?
Bioinformatics
How is bioinformatics used?
Medical security/privacy electronic medical records (databases) medical decision making tech assisted learning environments sequence analysis protein structural analysis and prediction
What is the study of how information is represented and transmitted in biological systems?
Bioinformatics
What is the central dogma presented by Watson and Crick?
DNA makes RNA. RNA codes for proteins.
DNA is made up of 3 things. What are they?
- Sugar: Deoxyribose
- Phosphate: the backbone
- Base: ATGC
DNA is made up of nucleotides? These contain…
1 sugar, 1 phosphate, 1 base
Adenine, guanine, cytosine, thymine are what?
The bases found in DNA
What nucleic acid has a double helix?
DNA
DNA is similar to a ladder in structure.What are the rungs of the ladder in DNA made of?
the bases!
Sugar does what in the nucleotide?
Bonds the phosphate to the base
What did Watson and Crick discover?
The base pairs will always be AT and CG.
DNA is in a double helix structure
A common desire of researchers in biotechnology is?
To discover the killer application that will be the app of the future
example: designer drugs
The killer app (just-in-time) designer drug system requires:
- high throughput screening: obtains genetic profile quickly
- medically relevant information gathering: Based on symptoms
- custom drug synthesis: based on patient GC
The killer app must have consistency and specificity in a _________.
controlled vocabulary
When DNA is opened and a section is copied to make RNA,_______ took place.
transcription
Transcription happens in ________
the nucleus
_______ reads DNA one nucleotide as a time and creates ________
RNA Polymerase
RNA
What nucleotides pair in RNA?
Adenine-Uracil, Guanine-Cytosine
After transcription, the RNA moves in _____ where ______ reads codons.
the cytoplasm
ribosomes
A codon is made up of _____
3 nucleotides
An amino acid is ____
1 codon or 3 nucleotides.
we have 20 amino acids all together
A chain of amino acids is _____
A protein
All enzymes are proteins.
true
All proteins are enzymes.
False
_____ is a start codon?
AUG: Methianine
Scientific research that starts from large truths and seeks details from a bigger picture is….
Top down research style
Doctor would use this
Scientific research that starts from the details and works its way to the big picture (DNA to the body’s physical appearance)
Bottom up research style
a geneticist would use this
Numbers or other identifiers derived from observation, experiment or calculation
Data
data in context is..
information
descriptions of data or data put into context that is then summarized
metadata
What is crucial to know when collecting information or building a database?
Target audience
These serve as controllers, information archives, asynchronous communication devices, and numerical processors.
computers
Computers serve as…
Controllers, archives of info, communication devices, and number crunchers
Why are computer controlled devices preferable over manual controlled devices when time is limited?
They can run around the clock and therefore have a greater output in a shorter time.
What is the one thing biological databases have in common?
enormity of content
A disk server can…
NOT A DATABASE
- act as a remoter disk drive
- can open or limit access to diff. areas
- allows multiple users to open the same file (which can cause issues)