Midterm 1,2,3, &17 Flashcards
Cells
living things that create energy
Levels of biological organization
Atom + Molecule, Cell, Tissue, organ, organ systems
two types of cells
Prokaryotic and Eukaryotic which contain DNA and plasma membrane
Prokaryotic
simple, no organelles
Eukaryotic
complex, has organelle and nucleus
Element
a substance that cannot be broken down to other substances
Essential Elements
Carbon (c), Oxygen (o), Hydrogen (h), Nitrogen (n) which makes up 96% of 22.2% essential natural elements
Remaining 4% of essential natural elements
Phosphorus (p), Sulfur (s), Calcium (ca), Potassium (k)
Trace elements
Required in minute qualities, Iron (fe) - Carries oxygen
Iodine (I) Thyroid gland essential ingredient to make hormones
Metabolism
Energy is utilized in chemical reactions called metabolism
Homeostasis
regulate cells to maintain stable internal conditions
Nucleus
contains dna
Subatomic particles
parts composing an atom
Element defiency
could lead to disease in both plants and animals
3 main subatomic particles
Neutrons, Protons, and Electrons
Electric charges
Only protons and electrons are electrically charged
Protons
One unit of positive charge
Electron
One unit of negative charge
Atomic number
Number of protons in an element, written as the subscript to the left of an element
Atomic mass
Mass of protons + mass of neutrons
One dalton
One mass - mass number
Isotopes
different atomic forms of an element, has the same number of protons but different numbers of neutrons
Radioactive Isotopes applied
tracers of metabolism, monitor cellular function and processes such as cell division and mitosis
Chemical bonds
Atom attractions that combine to form and hold together molecules and ionic compounds
Covalent bond
the sharing of electrons by two atoms, strongest bond in nature
Weak chemical bonds
Most important macromolecules are held in their functional forms by weak bonds
Weak bonds are
Ionic and Hydrogen bonds
Ionic bonds
charged molecules are ions, occurs between oppositely charged ions
Hydrogen bonds
Formed when a hydrogen atom covalently bonded to one electronegative atom is attracted to another one of its kind
Electronegative atom
oxygen and nitrogen
Water
Polar molecule held together by hydrogen
Acid
Substance that donates hydrogen while dissolving in water
Base
substance that reduces the concentation of hydrogen directly or indirectly in a solution. accept hydrogen ions
what do these do?
Acids
proton donors
Buffer solution
solution with minimal changes of H+ and OH- concentrates, minimizes ph changes
Macromolecules
DNA and Carbohydrates
The four large molecules in cells
Carbohydrates, Lipids, proteins, and nucleic acids
Types of carbohydrates
Monosaccharides, oligosaccharides, polysaccharides
Carbohydrates
participate in..
energy storage and provide structural support
Monosaccharides
main fuel that cells use for cellular work
Disaccharides
double sugar, constructed from two monosaccharides and are joined through a dehydration reaction
Types of disaccharides
Lactose and Sucrose
what are
Polysaccharides
Complex carbohydrates and long chains of sugar
Cellulose
Structural support, most abundant organic compound on earth. Dietary fiber.
Glycogen
Stores energy
Lipids
insoluble in water
Triglycerides
energy storing molecules
Phosolipids
Cell membranes, structural components of cells, one side is soluble and the other is insoluble in water
Steroids
Carbon based ring structures
Cholesterol
Used in making estrogen and testosterone, base steroids
LDL
bad cholesterol, can lead to heart disease
HDL
good cholesterol recycled by liver
Amino acids
consist of
central carbon atom bonded to four covalent partners
Secondary amino structure
Alpha, helix, and beta sheet
Tertiary sequence
describes 3 dimensional shape created by disulfide and hydrogen bonds. creates polar and nonplar areas in molecules
Quartinay sequence
describes proteins in which two or more tietary protein chains are associted
Enzymatic catalysis
boosts chemical reaction
Himoglobins
transport 02 in red blood cells
Myoglobin
transports 02 in muscles
Ferritin
Iron stored in liver
Enzyme Function
dependent on the temperature of reaction medium, ph levels, ion concentration and precence of inhibitors
Nucleic acid functions
Store genetic information, provides info used in making proteins
Nucleic acid structure
nucleotides consist of a phosphate group, a sugar, and a nitrogenous base
DNA
Double helix : 2 associated strands of nucleic acid : Contains Deoxyribose
DNA nitrogenous bases
Adenine - Thymine, Cytosine - Guanine
RNA
SIngle stranded nucleic acid : passes along genetic messages : contains ribose
RNA nitrogenous bases
Adenine - Uracil, Cytosine - Guanine
Polypeptide
long chain of amino acids that makes proteins
polynucleotide
A polymer made up of many nucleotides covalently bonded together
Plasma membrane is made up of
phosolipids, cholesterol, protein and carbohydrates
Nucleotides
Basic units of DNA molecule, composed of a sugar, a phosphate, and one of 4 DNA bases
Prokaryotic DNA
one single chromosome to attached cell membrane
Phosolipids
found in all cell membranes. have polar and nonpolar tail
plasma membrane
A phospholipid bilayer forming the boundary of the cells
Protein in membranes
Assist other molecules to move in and out of the membrane
Membrane transport
the movement of ions or molecules across the cell membrane
Passive transport (diffusion)
a process that requires no energy to move molecules down their concentration gradient (from high to low concentation)
Active transport
An energy-requiring process that moves material across the cell membrane against a concentration difference. (Facilitated transport)
Osmosis and Diffusion
two types of transport, moves water through semipermable membrane
Endocytosis
process in which cell takes material into the cell via infolding of the cell membrane
Exocytosis
process in which cells release large amounts of material
Tonicity
the ability of a solution to cause a cell to gain or lose water
Isotonic
when the concentration of two solutions is the same
hypotonic
having a lower concentration of solute than other solution, cell will swell and burst water
hypertonic
having a higher concentration of solute than other solution, cell can break (lysis)
Plastids (chloroplast)
Used for storage and making food (photosynthesis)
Only in plant cells and contains the color pigment
Passive transport happens as
DIffusion through lipid layer and through protein channels
Amyloplast
unpigmented plastids that store startch grains. abundent in cells of stems
Nucleus function
the command center of the cell that contains genetic material and chromosomes
Nucleus structure
Bonded by double membrane and contains DNA
Ribosomes
used in protein assembly, free and membrane bound
Rough Endoplasmic Reticulum (ER)
the region of ER that is studded with ribosomes and engages in protein modification
Smooth Endoplasmic Reticulum
The region of ER that doesn’t have ribosomes attached to it, involved in synthesis and secretion of lipids
Golgi appartus
a system of membranes that modifies and packages proteins for export by the cell
Vesicles
small membrane sacs that specialize in moving products into, out of, and within the cell
Lysomes
contains digestive enzymes, removes foreign material and waste from the cell
Enzymes
break down macromolecules
Mitochondria
organelle that is the site of ATP (energy) production, site of cellular respiration, has its own DNA, and contains ribosomes
Cytoskeleton
a network of fibers that hold the cell together, helps cells keep their shape, and aids in movement
Cilia and Flagella
used in cell structures for support and movement. Cilia moves back and forth, Flagella moves in a whip-like motion
Mitosis
part of eukaryotic cell division during which the cell nucleus divides and DNA distributes
Sequence of Mitosis
prophase, metaphase, anaphase, and telophase + cytokinesis
Mitosis passing on genes
before parent cell divides and duplicates its DNA (chromosomes), resulting in daughter cells that are genetically identical
Karyotope
orderly arrangement of chromosomes
Homologous chromosomes
matching pairs of chromosomes
Diploid organisms
Humans are diploid organisms, with 23 pairs of chromosomes in each cell, or 46 chromosomes in total.
Haploid organisms
our gamates (germ line cells) are haploid, only has one set of chromosomes
Prophase in mitosis
Chromatin fibers condense
Metaphase in mitosis
Chromosomes align on the metaphase plate
Anaphase
separation of sister chromatids, movement of chromosomes towards opposite ends
Telophase + Cytokinesis
formation of two daughter nuclei in the cell, end of mitosis and beginning of division of cytoplasm
Meiosis
haploid daughter cells being produced in diploid organisms, main goal is 2 cell divisions and ends in 4
Crossing over
homologous chromosomes exchange genetic info. Occurs in meiosis (prophase I) but not in
normal mitosis
Interphase
What follows after Miosis 1 and Miosis 2, chromosome replication of two genetically identical chromosome sisters
Key roles of meiosis
Preparation to fertilization, reduction of number of chromosome sets from diploid to haploid
Sexual reproduction depends on
Meiosis: diploid + haploid stages
fertalization
Prophase 1 (miosis)
takes about 90% of the time that mitosis takes, chromosomes begin to condense, crossing over, breakdown of nuclear envolope
Metaphase 1
Pairs of homologous
chromosomes forming tetrads
aligning on the metaphase plate. attached to microtubules from one pole
Anaphase 1
Movement of chromosomes
towards opposite ends: homologous chromosomes (two sister chromatids) toward opposite pole
Telophase + Cytokineses in miosis
Each half of the cell has a complete haploid set of chromosomes, still composed of two sister chromatids. occur
simultaneaously
Prophase 2
Formation of spindle apparatus. Beginning of chromosome
movement toward the metaphase II plate
Metaphase 2
Chromosomes align on the
metaphase plate as in mitosis
Anaphase 2
The centromeres of each
chromosome finally separate and sister chromatids come apart - toward opposite
poles
Telophase 2 + Cytokinesis
Chromosomes begin decondensing, Cytokinesis
produces 4 daughter cells, each
with a haploid set of chromosomes and are
genetically distinct
Mitosis vs Meiosis
Meiosis reduces number of chromosome sets from
diploid to haploid
Mitosis conserves the number of chromosome set
Sex differences in meiosis
Males: 4 sperm produced from each meiotic division; all viable.
* Female: one egg produced fromeach meiotic division; meiosis II is not complete until fertilization.
Cell cycle regulation
control mechanisms that determine whether cells will divide, remain dormant, arrest, or undergo programmed cell death
Accidents in meiosis
The members of a chromosome pair fail to separate or Gametes with an incorrect number of chromosomes are
produced.
Examples of meiosis accidents