Midterm 1 Flashcards
Vertebral arteries
brainstem and cerebellum
Internal carotid arteries
provides 80%
supplies most of telencephalon and diencephalon
What areas would be affected from the occlusion of the Anterior Cerebral Artery?
leg and hip regions
What areas would be affected from the occlusion of the Middle Cerebral Artery?
arms and facial regions
Craniorachischisis
open spinal cord and spine
CNS is abnormally open on its dorsal surface
Anencephaly
failure of the rostral end of the neural tube
to close
Spina bifida
failure of the caudal end of the neural tube
to close
Primary Brain Vesicles
bulges and kinks appear along the anterior-posterior extent of the neural tube (prosencephalon, mesencephalon, rhombencephalon)
Secondary Brain Vesicles
prosencephalon (forebrain) - telencephalon & diencephalon
mesencephalon (midbrain)
rhombencephalon (hindbrain) - metencephalon & myelencephalon
Derivatives of Secondary Vesicles
telencephalon - cerebrum
diencephalon - thalamus, hypothalamus, retina, midbrain structures
mesencephalon - midbrain
metencephalon - pons, cerebellum
myelencephalon - medulla
Holoprosencephaly
partial/complete failure of the prosencephalon to separate into the diencephalon & paired telencephalon vesicles
- caused by too little hedgehog signaling
Cyclopia
extreme case of holoprosencephaly; single brain vesicle w/ large fused single midline eye
Tangential Migration
new born neurons arise from the ganglionic eminence in ventral striatum
- migrate long distances through the developing neocortex to supply inhibitory neurons
Radial Migration
new born neurons arise at the ventricular surface and migrate upwards in a radial pattern to form cortical pyramidal neurons (excitatory)
Spinothalamic tracts pathway (orders)
1st - dorsal root ganglia
2nd - nucleus proprius
3rd - thalamus
cross - in spinal cord, prior to entering tracts
Spinocerebellar tracts pathway (orders)
only second order
1st - dorsal root ganglia
2nd - neurons in spinal cord
ipsilateral but ventral cerebellar tract undergoes double cross in spinal cord then brainstem
Corticospinal tracts pathway order
1st - motor, premotor, and supplemental motor cortices (upper motor neurons)
2nd - spinal cord (generally interneurons)
contralateral
crosses - medulla oblongata (lateral) and in spinal cord (anterior)
Brainstem tracts (involuntary) (4)
- vestibulospinal (locomotor reflex and balance)
- tectospinal (head and eye movement, direct toward sights and sound; terminates in cervical spinal cord)
- reticulospinal (postural control and locomotion)
- rubrospinal (locomotion; terminates in cervical and thoracic spinal segments - responsible for trunk and upper limbs)
Division of spinal segments
31
- 8 cervical
- 12 thoracic
- 5 lumbar
- 5 sacral
- 1 coccygeal
Division of Vertebrae
33
- 7 cervical
- 12 thoracic
- 5 lumbar
- 5 sacral
- 4 coccygeal
Foramen Magnum
the space that the spinal cord passes through to connect to the brainstem
Passing order of vertebrae & spinal segments
- first 7 cervical pass above respective vertebrae, 8th pass above first thoracic vertebra (below 7th)
- remaining nerves pass below vertebrae
- 4 coccygeal vertebrae fused; passes below first coccygeal vertebra
- sacral segments also fused
Dermatomes
areas of skin whose sensory info project via certain spinal nerves
superior and inferior articular process
help connect vertebrae to one another via facet joint