Micturition Flashcards
Excretion
• Urine composition is very different to filtrate
– Important molecules are reabsorbed (eg. Glucose, amino acids)
– Waste products are concentrated (eg. Urea, drugs)
– Ions & water vary depending on blood concentration
Transport & storage of urine
Ureters – Transports urine to bladder • Bladder – Storageofurine – Stretches to accommodate urine, contracts during voiding • Urethra – Transports urine to exterior – Transit of urine is controlled by sphincters Kidneys Ureters Bladder Urethra
Micturition involves the relaxation of two sphincters
Internal urethral sphincter • Smooth muscle
• Involuntary
External urethral sphincter
• Skeletal muscle
• Voluntary
Micturition reflex
- Micturition reflex is involuntary & controlled at the spinal cord
- Filling of the bladder stimulates stretch receptors
- Triggers parasympathetic stimulation of the bladder muscle (contraction)
- Internal sphincter opens
- Micturition reflex inhibits motor neurons innervating the external urethral sphincter
- Voluntary signals from cerebral cortex over- rides inhibition of motor neurons
reflex control
bladder fills > stimulates stretch receptors > stim. parasympathetic nerve > bladder > bladder contracts > internal urethral sphincter mechanicallyopens when bladder contracts > urination
voluntary control
voluntary control by controlling external urethra
cerebal cortex > MN to external scphinter >
1. external urethral scphinter opens when MN is inhibited > urination
or
2. > external urethral scphincter remains closed when MN stimulated > no urination