Microscopy

Question 1

What is sensitivity and specificity of microscopy for detection of GC in a symptomatic male?

Answer 1

Sensitivity 90-95%

Specificity 95-99%

Question 2

What is sensitivity of microscopy for detection of GC in an asymptomatic male?

Answer 2

Sensitivity 50-75%

Question 3

What is sensitivity and specificity of microscopy for detection of GC in an MSM rectal sx?

Answer 3

Sensitivity 40% blind - 50-75% proctoscope

Specificity- 95-100%

Question 4

What is sensitivity and specificity of microscopy for detection of GC in the cervix?

Answer 4

Sensitivity 37-50%

Specificity- 88-100%

Question 5

What is sensitivity and specificity of microscopy for detection of BV in vagina?

Answer 5

Sensitivity 97.5%

Specificity- 96%

Question 6

What is sensitivity and specificity of microscopy for detection of TV in vagina?

Answer 6

Sensitivity 40-80%

Specificity- 100% if protozoa

Question 7

What is sensitivity of microscopy for detection of TV in male urethra?

Answer 7

Sensitivity 30%

Question 8

What is sensitivity of microscopy for detection of candida in vagina (gram stain)

Answer 8

65%

Question 9

What is sensitivity of microscopy for detection of candida in vagina (saline prep)

Answer 9

40-60%

Question 10

What is sensitivity and specificity of microscopy for detection of syphilis from an ulcer?

Answer 10

Sensitivity- 79-86%

Specificity- 77-100%

Question 11

Sensitivity?

Answer 11

The number of people with the disease who have a positive test

Question 12

Specificity

Answer 12

The number of people who don’t have the disease who have a negative test

Question 13

Why is there resistance with GC (isolates with decrease in antimicrobial sensitivity?)

Answer 13

May be due to plasmids- circular DNA - independent of chromosomes/chromosomal mutation

Question 14

What is sampling suggested for GC if woman has had a hysterectomy?

Answer 14

no evidence on optimal sampling site.

Suggest considering urine and VVS NAAT with subsequent culture from that site if positive