Micromertics

Question 1

What is micromeritics?

Answer 1

Micromeritics is the branch of science that deals with the study of small particles which is the range of micrometers.

Question 2

The scale of micrometeritics

Answer 2

I micrometer = 10^-6 m / 10^-4cm/ 10^-3 mm

Question 3

Micromeritics deals with

Answer 3

Fundamentals properties of particles and derived properties of particles and their influence on manufacturing process, drug release and selection of packaging systems etc

Question 4

Particle size influence on dissolution rate which inturn influence on the absorption and bioavailability

Answer 4

Lesser the particle size higher the surface area and larger the absorption and bioavailability

Question 5

Particle size determines the stability of the drug

Answer 5

Lower the particle size lesser the sedimentation rate and higher the stability of the suspension

Lower the globule size lesser the rate of creaming and greater the stability of the emulsion

Question 6

Lesser the particle size higher will be the mixing efficiency and higher the drug uniformity h

Answer 6

Higher the surface area higher will be the rate of dissolution , absorption and bioavailability

Question 7

Spherical and symmetrical particle shape can result in better flow property compressibility and ease of manufacturing

Question 8

Particle number determination can provide the information regarding density and porosity

Question 9

Density porosity and bulkiness determination can provide information regarding drug release packing arrangements selection of containers manufacturing equipments etc

Question 10

Determination of flow properties can help to select the ideal powder blend which is suitable for processing as tablet or capsule

Question 11

All micromeritic properties can actually as quality control test for raw materials used in the manufacturing