Microcytic Anemias Lecture Powerpoint Flashcards

Amber this time round

1
Q

Hemoconcentration

A

Increase in proportion of RBC’s relative to the plasma

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2
Q

Hemodilution

A

Decrease in proportion of RBC’s relative to plasma

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3
Q

A problem with the alpha or B protein chains on the hemoglobin is what type of disorder?

A

Thalassemia

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4
Q

Porphyria definition

A

Presence of an altered heme porphyrin ring on the hemoglobin molecule resulting in microcytic hypochromic anemia, very very very rare condition

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5
Q

Sideroblastic anemia definition, how does it appear on a peripheral smear?

A

Occurs when bone marrow produces ringed sideroblasts opposed to proper RBC’s
Appears to have central pallor in it like a donut hole

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6
Q

The number 1 cause of hypochromatic, microcytic anemia

A

Iron deficiency anemia

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7
Q

Heme iron vs non heme iron absoprtion rate (animal vs plant product)

A

Heme iron is absorbed much better than non heme

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8
Q

Most common type of anemia in the world

A

Iron deficiency anemia

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9
Q

Most common cause of iron deficiency anemia in US

A

Not diet, but actually blood loss

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10
Q

Hematemesis definition

A

Vomitting of blood

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11
Q

Melena definition

A

Dark colored bloody stool indicative of upper GI bleed

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12
Q

Hematochezia definiton

A

Light colored bloody stool indicative of colon bleeding

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13
Q

Pica definition and examples indicative of iron deficiency

A

Eating items not considered food, ice, clay, and starch are examples

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14
Q

Plummer-Vinson syndrome triad of symptoms

A
  • iron deficiency anemia
  • dysphagia
  • esophageal webs
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15
Q

Most common symptom seen in a patient suffering a PE

A

Tachycardia

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16
Q

Angular stomatitis is indicative of…

A

…iron deficiency anemia

17
Q

Koilonychia definition and what is it indicative of?

A

abnormally thin spoon nails, indicative of iron deficiency anemia

18
Q

All RBC indices will be ___ in microcytic hypochromatic anemia

A

Low

19
Q

Serum ferritin test function

A

The most reliable gold standard test for evaluation of iron present in serum

20
Q

Iron deficiency sees serum iron ___, total iron bindig capacity ___, and serum ferritin ____

A
  • decrease
  • increase
  • decrease
21
Q

Sideroblastic anemia is a __cytic, ___chromatic anemia with iron ____

A

micro, hypo, overload

22
Q

Acquired sideroblastic anemia sources (4)

A
  • alcohol
  • lead
  • B6 deficiency
  • lupus
23
Q

Sideroblastic anemia will have a ____chromatic peripheral smear with something called ____

A

hypo, basophilic stippling

24
Q

Target cells on peripheral smears are indicative of…

A

….thalassemia

25
Q

Sideroblasic anemia treatment

A

Chelation therapy