microcirculaton sections I & II

Question 1

capillaries are the site for ___/____ products & ______ exchange

Answer 1

nutrient/waste products

fluid - vascular/interstitial

Question 2

the smooth m of the metarteriols and capillaries (pre-capillary sphincter) produce the mechanism of ________ and regulate the amount of flow to tissue.

Answer 2

TPR

Question 3

capillary endothelium is thin walled & a ______ layer thick.

Answer 3

single

Question 4

in most capillaries the narrow water filled ___ are present between cells and permit passage of water-soluble substances.

Answer 4

pores

Question 5

lipid soluble substances like O2 & CO2 can readily pass through the _______ by dissolving in the lipid bilayer barrier via _______ _______.

Answer 5

endothelium

vascular transport

Question 6

what effect do histamines have on capillary pores?

Answer 6

widens them to allow the pass of wbc’s

Question 7

the degree of resistance offered by the arterioles in the organ is controlled by sympathetic activity & _______ _______.

Answer 7

local metabolites

Question 8

the number of open capillaries is controlled by the action of _______ _________ on smooth m of terminal arterioles & precapillary sphincters.

Answer 8

local metabolites

Question 9

how is exchange between capillary plasma & ISF accomplished?

Answer 9

1. passive diffusion - primary mechanism for exchange of individual solutes.
2. bulk flow - movement of protein free plasma across the capillary wall and surrounding ISF.- (filtration & reabsorption)

Question 10

hydraulic conductance determines what in the capillaries?

Answer 10

how difficult it is for fluid to get out of the vessel

- how much fluid movement will be produced for a given pressure difference

Question 11

______ pressure has a larger effect on hydrostatic pressure changes than _______ pressure in the capillary.

Answer 11

venous

arteriole

Question 12

capillary osmotic pressure is maintained by?

Answer 12

plasma [protein]
to large to leave the capillary
ie. ALB, globulins, fibronogen

Question 13

what facilitates interstitial osmotic pressure?

Answer 13

protein that escaped the capillary

- not much escapes in the healthy animal thus this value is near 0

Question 14

2 forces that tend to move fluid out of the capillary are?

Answer 14

1. capillary BP

2. interstitial Osmotic pressure

Question 15

2 forces that tend to move fluid into the capillary are?

Answer 15

1. capillary osmotic pressure

2. interstitial hydrostatic pressure

Question 16

what is filaris? and how does it cause?

Answer 16

blockage of lymph vessel do to microfilaria worms leads to edema