Microbiology [PATH] Flashcards
1
Q
What are the 3 common sites of action of antibiotics in bacteria
A
- Peptidoglycan cell wall
- Inhibition of bacterial protein synthesis
- DNA gyrase and other prokaryote-specific enzymes
2
Q
Which classes of antimicrobials are inhibitors of cell wall synthesis?
A
β-lactams: Penicillins, Cephalosporins, Carbapenems
Glycopeptides
3
Q
How does gram positive bacteria cell wall differ from gram negative?
A
• Gram-positive cell wall – thick peptidoglycan cell wall (made of NAG and NAM components)
Gram-negative cell wall – thin peptidoglycan cell wall, outer membrane conferring resistance to some ABx
o Can be more resistant and harder to treat due to outer membrane
4
Q
Types of beta-lactam?
A
Penicillins
Cephalosporins
Carbapenams
