microbiology exam 4 Flashcards
list and explain the innate immune system response such as 1 2 3 line of defense
first line defense- prevent microbial entry- that is skin and mucous membranes and antimicrobial substances
Detect damage and microbial invasion - pattern recognition receptors and complement system
Innate effector actions- eliminate invador- phagocytosis
complement activation
interferon response
fever
what are the Activated complement proteins play a part in eliminating microbial invaders from a host. They belong to the group of non-specific immune responses.
phagocytosis
inflammation
fever
interferon
What does the complement system made up of
The complement system is made up of proteins found in the bloodstream.
where does the complement system components react
in a cascade
where are complement proteins found
the serum
How is the classical complement pathway is activated?
When C1 binds to the antifgen- antibody complex
What does C3 convertase cleaves C3 into
C3a and C3b
what is the purpose of C3b
C3b binds to the surface of microorganisms and phagocyte receptors