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Pathology blackboard questions > Microbiology > Flashcards

Microbiology Flashcards

1
Q

The antiviral which is given to untreated pregnant women with HIV to prevent vertical transmission of the virus during childbirth.

All Answer Choices
A. Cidofovir
B. Entecevir
C. Interferon-g (gamma)
D. Ganciclovir
E. Oseltamivir
F. Interferon-b (beta)
G. Neuraminidase inhibitor
H. Aciclovir triphosphate
I. Nevirapine
J. Aciclovir
K. Interferon-α (alpha)
L. Aciclovir monophosphate
M. Ribavirin
N. Foscarnet
O. Zidovudine
A

I. Nevirapine

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2
Q

An immunomodulatory therapy used in the treatment of hepatitis B.

All Answer Choices
A. Cidofovir
B. Entecevir
C. Interferon-g (gamma)
D. Ganciclovir
E. Oseltamivir
F. Interferon-b (beta)
G. Neuraminidase inhibitor
H. Aciclovir triphosphate
I. Nevirapine
J. Aciclovir
K. Interferon-α (alpha)
L. Aciclovir monophosphate
M. Ribavirin
N. Foscarnet
O. Zidovudine
A

K. Interferon-α (alpha)

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3
Q

An antiviral currently used to prevent and treat Influenza in the elderly and which has the potential to be used to prevent Avian influenza.

All Answer Choices
A. Cidofovir
B. Entecevir
C. Interferon-g (gamma)
D. Ganciclovir
E. Oseltamivir
F. Interferon-b (beta)
G. Neuraminidase inhibitor
H. Aciclovir triphosphate
I. Nevirapine
J. Aciclovir
K. Interferon-α (alpha)
L. Aciclovir monophosphate
M. Ribavirin
N. Foscarnet
O. Zidovudine
A

E. Oseltamivir

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4
Q

The final metabolite of the antiviral used to treat Herpes Simplex

All Answer Choices
A. Cidofovir
B. Entecevir
C. Interferon-g (gamma)
D. Ganciclovir
E. Oseltamivir
F. Interferon-b (beta)
G. Neuraminidase inhibitor
H. Aciclovir triphosphate
I. Nevirapine
J. Aciclovir
K. Interferon-α (alpha)
L. Aciclovir monophosphate
M. Ribavirin
N. Foscarnet
O. Zidovudine
A

H. Aciclovir triphosphate

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5
Q

An antiviral which can be used in aerosol form to prevent respiratory syncytial virus in children with heart and lung disease

All Answer Choices
A. Cidofovir
B. Entecevir
C. Interferon-g (gamma)
D. Ganciclovir
E. Oseltamivir
F. Interferon-b (beta)
G. Neuraminidase inhibitor
H. Aciclovir triphosphate
I. Nevirapine
J. Aciclovir
K. Interferon-α (alpha)
L. Aciclovir monophosphate
M. Ribavirin
N. Foscarnet
O. Zidovudine
A

M. Ribavirin

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6
Q

Which option is the product of the action of viral tyrosine kinase on aciclovir?

All Answer Choices
A. Famciclovir
B. Guanosine
C. Thymidine
D. Varicella-zoster virus
E. Aciclovir triphosphate
F. Aciclovir diphosphate
G. AIDS
H. Ribavarin
I. Cytomegalovirus
J. Aciclovir monophosphate
K. Influenza
A

J. Aciclovir monophosphate

Aciclovir diphosphate and triphosphate are the product of cellular tyrosine kinase, whereas aciclovir monophosphate is the product of viral tyrosine kinase.

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7
Q

Which option inhibits the action of viral DNA polymerase?

All Answer Choices
A. Famciclovir
B. Guanosine
C. Thymidine
D. Varicella-zoster virus
E. Aciclovir triphosphate
F. Aciclovir diphosphate
G. AIDS
H. Ribavarin
I. Cytomegalovirus
J. Aciclovir monophosphate
K. Influenza
A

E. Aciclovir triphosphate

Aciclovir diphosphate and triphosphate are the product of cellular tyrosine kinase, whereas aciclovir monophosphate is the product of viral tyrosine kinase.

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8
Q

The synthetic nucleoside analogue ganciclovir is the drug of choice against which infective virus?

All Answer Choices
A. Famciclovir
B. Guanosine
C. Thymidine
D. Varicella-zoster virus
E. Aciclovir triphosphate
F. Aciclovir diphosphate
G. AIDS
H. Ribavarin
I. Cytomegalovirus
J. Aciclovir monophosphate
K. Influenza
A

I. Cytomegalovirus

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9
Q

Ribavirin, a synthetic nucleoside that acts as an RNA polymerase inhibitor, is similar in structure to which of the options given above?

All Answer Choices
A. Famciclovir
B. Guanosine
C. Thymidine
D. Varicella-zoster virus
E. Aciclovir triphosphate
F. Aciclovir diphosphate
G. AIDS
H. Ribavarin
I. Cytomegalovirus
J. Aciclovir monophosphate
K. Influenza
A

B. Guanosine

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10
Q

Valaciclovir, a prodrug of aciclovir, is used to treat patients with which viral disease in the list?

All Answer Choices
A. Famciclovir
B. Guanosine
C. Thymidine
D. Varicella-zoster virus
E. Aciclovir triphosphate
F. Aciclovir diphosphate
G. AIDS
H. Ribavarin
I. Cytomegalovirus
J. Aciclovir monophosphate
K. Influenza
A

D. Varicella-zoster virus

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11
Q

An immunomodulator effective in HBV infection

All Answer Choices
A. Zidovudine
B. Gancyclovir
C. Ribavarin
D. Abacavir
E. Aciclovir
F. Citalapram
G. Amantadine
H. Adefovir
I. Interferon
J. Ibuprofen
K. Foscarnet
L. Doxacyclin
M. Loviride
A

I. Interferon

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12
Q

Used for the treatment of severe, resistant herpes infections

All Answer Choices
A. Zidovudine
B. Gancyclovir
C. Ribavarin
D. Abacavir
E. Aciclovir
F. Citalapram
G. Amantadine
H. Adefovir
I. Interferon
J. Ibuprofen
K. Foscarnet
L. Doxacyclin
M. Loviride
A

K. Foscarnet

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13
Q

The treatment of choice for CMV-induced hepatitis

All Answer Choices
A. Zidovudine
B. Gancyclovir
C. Ribavarin
D. Abacavir
E. Aciclovir
F. Citalapram
G. Amantadine
H. Adefovir
I. Interferon
J. Ibuprofen
K. Foscarnet
L. Doxacyclin
M. Loviride
A

B. Gancyclovir

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14
Q

A drug that is effective against influenza A but not influenza B

All Answer Choices
A. Zidovudine
B. Gancyclovir
C. Ribavarin
D. Abacavir
E. Aciclovir
F. Citalapram
G. Amantadine
H. Adefovir
I. Interferon
J. Ibuprofen
K. Foscarnet
L. Doxacyclin
M. Loviride
A

G. Amantadine

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15
Q

A purine nucleoside analogue that selects specifically for thymidine kinase

All Answer Choices
A. Zidovudine
B. Gancyclovir
C. Ribavarin
D. Abacavir
E. Aciclovir
F. Citalapram
G. Amantadine
H. Adefovir
I. Interferon
J. Ibuprofen
K. Foscarnet
L. Doxacyclin
M. Loviride
A

E. Aciclovir

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16
Q

A nucleoside analogue which inhibits reverse transcriptase

A. Zidovudine
B. Human specific immunoglobulin
C. Enfuvirtide
D. Nevirapine
E. Amantadine
F. Zanamivir
G. Interferon
H. Efavirenz
I. Ribavarin
J. Ganciclovir
K. Indinavir
L. Aciclovir
M. Human normal immunoglobulin
A

A. Zidovudine

17
Q

The drug mechanisms which acts by stopping post-translational cleaving of polyproteins by inhibiting proteases

A. Zidovudine
B. Human specific immunoglobulin
C. Enfuvirtide
D. Nevirapine
E. Amantadine
F. Zanamivir
G. Interferon
H. Efavirenz
I. Ribavarin
J. Ganciclovir
K. Indinavir
L. Aciclovir
M. Human normal immunoglobulin
A

K. Indinavir

18
Q

The drug that is selectively toxic to virally infected cells through its selective phosphorylation using viral thymidine kinase

A. Zidovudine
B. Human specific immunoglobulin
C. Enfuvirtide
D. Nevirapine
E. Amantadine
F. Zanamivir
G. Interferon
H. Efavirenz
I. Ribavarin
J. Ganciclovir
K. Indinavir
L. Aciclovir
M. Human normal immunoglobulin
A

L. Aciclovir

19
Q

The drug which can be delivered by inhalation to treat both influenza A and B.

A. Zidovudine
B. Human specific immunoglobulin
C. Enfuvirtide
D. Nevirapine
E. Amantadine
F. Zanamivir
G. Interferon
H. Efavirenz
I. Ribavarin
J. Ganciclovir
K. Indinavir
L. Aciclovir
M. Human normal immunoglobulin
A

F. Zanamivir

20
Q

The drug which works by attenuating or preventing rabies or hepatitis, following a known exposure but before the onset of signs and symptoms.

A. Zidovudine
B. Human specific immunoglobulin
C. Enfuvirtide
D. Nevirapine
E. Amantadine
F. Zanamivir
G. Interferon
H. Efavirenz
I. Ribavarin
J. Ganciclovir
K. Indinavir
L. Aciclovir
M. Human normal immunoglobulin
A

B. Human specific immunoglobulin

21
Q

The drug which works by attenuating or preventing rabies or hepatitis, following a known exposure but before the onset of signs and symptoms.

A. Zidovudine
B. Human specific immunoglobulin
C. Enfuvirtide
D. Nevirapine
E. Amantadine
F. Zanamivir
G. Interferon
H. Efavirenz
I. Ribavarin
J. Ganciclovir
K. Indinavir
L. Aciclovir
M. Human normal immunoglobulin
A

B. Human specific immunoglobulin

22
Q

A 40yr old female non-smoker presents with a one week history of fever, shortness of breath and a cough productive of rusty coloured sputum. She complains of a sharp chest pain which “catches” her on inspiration. On examination she has increased vocal resonance in the right middle zone on auscultation. The x-ray shows right middle lobe consolidation.

All Answer Choices
A. S. pneumoniae
B. B. pertussis
C. K. pneumoniae
D. M. pneumoniae
E. P. aeuruginosa
F. L. pneumophila
G. C. neoformans
H. [None]
I. C. psittaci
J. M. tuberculosis
K. S. aureus
A

A. S. pneumoniae

23
Q

A 37yr old American business man staying in a hotel presents with a headache, myalgia and a dry cough. He is also suffering with nausea, diarrhoea and abdominal pain. On examination he is tachypnoeic and has a pyrexia of 39ºC. Blood tests reveal lymphopenia and hyponatraemia.

All Answer Choices
A. S. pneumoniae
B. B. pertussis
C. K. pneumoniae
D. M. pneumoniae
E. P. aeuruginosa
F. L. pneumophila
G. C. neoformans
H. [None]
I. C. psittaci
J. M. tuberculosis
K. S. aureus
A

F. L. pneumophila

24
Q

A 19yr old medical student who lives in residential halls presents with a one week history of headache, malaise, shortness of breath and a cough. Her WBC is not raised but tests reveal the presence of cold agglutinins.

All Answer Choices
A. S. pneumoniae
B. B. pertussis
C. K. pneumoniae
D. M. pneumoniae
E. P. aeuruginosa
F. L. pneumophila
G. C. neoformans
H. [None]
I. C. psittaci
J. M. tuberculosis
K. S. aureus
A

D. M. pneumoniae

25
Q

A 30yr old lady presents with a three week history of tiredness, malaise, cough and weight loss. She feels her condition has worsened in the past week and she now also suffers from a fever and haemoptysis. In addition she complains of a “tender lump” in her supraclavicular region. Chest x-ray demonstrates nodular shadowing of the right upper zone.

All Answer Choices
A. S. pneumoniae
B. B. pertussis
C. K. pneumoniae
D. M. pneumoniae
E. P. aeuruginosa
F. L. pneumophila
G. C. neoformans
H. [None]
I. C. psittaci
J. M. tuberculosis
K. S. aureus
A

J. M. tuberculosis

26
Q

A forty year old ornithologist presents with malaise, muscular pains and a cough. On examination he has a fever and several distinctive rose spots on his abdomen. Chest x-ray reveals a diffuse pneumonia.

All Answer Choices
A. S. pneumoniae
B. B. pertussis
C. K. pneumoniae
D. M. pneumoniae
E. P. aeuruginosa
F. L. pneumophila
G. C. neoformans
H. [None]
I. C. psittaci
J. M. tuberculosis
K. S. aureus
A

I. C. psittaci

27
Q

Dry cough, new infiltrates on CXR, dyspnoea and target shaped lesions on the palms. No recent history of herpes.

All Answer Choices
A. S. pneumoniae
B. B. pertussis
C. K. pneumoniae
D. M. pneumoniae
E. P. aeuruginosa
F. L. pneumophila
G. C. neoformans
H. [None]
I. C. psittaci
J. M. tuberculosis
K. S. aureus
A

D. M. pneumoniae

28
Q

An 80 year old clown appears at the GP having been discharged from hospital for a complicated bowel resection with a stint in the ITU. He has a cough and fever and is prescribed a macrolide antibiotic because he is penicillin allergic.

All Answer Choices
A. Anaerobic infection
B. Chlamydia pneumoniae
C. M tuberculosis
D. Burkholderia cepacia
E. M. Catarrhalis
F. S. pneumoniae
G. Legionella pneumophila
H. MSSA
I. MSSA or MRSA
J. MRSA
K. Chlamydia psittaci
L. H. influenzae
M. PCP/ P jiroveci
A

H. MSSA

29
Q

A 55 year old female clown, recovering from a cold, is found to have a cavitating lesion on CXR and a productive cough.

All Answer Choices
A. Anaerobic infection
B. Chlamydia pneumoniae
C. M tuberculosis
D. Burkholderia cepacia
E. M. Catarrhalis
F. S. pneumoniae
G. Legionella pneumophila
H. MSSA
I. MSSA or MRSA
J. MRSA
K. Chlamydia psittaci
L. H. influenzae
M. PCP/ P jiroveci
A

I. MSSA or MRSA

30
Q

An 18 year old trainee clown is being seen in the cystic fibrosis clinic and is found to be colonised with a particularly persistent organism.

All Answer Choices
A. Anaerobic infection
B. Chlamydia pneumoniae
C. M tuberculosis
D. Burkholderia cepacia
E. M. Catarrhalis
F. S. pneumoniae
G. Legionella pneumophila
H. MSSA
I. MSSA or MRSA
J. MRSA
K. Chlamydia psittaci
L. H. influenzae
M. PCP/ P jiroveci
A

D. Burkholderia cepacia

31
Q

A 40 year old clown specialist is found to have a lobar pneumonia which on culture grew Gram +ve diplococci.

All Answer Choices
A. Anaerobic infection
B. Chlamydia pneumoniae
C. M tuberculosis
D. Burkholderia cepacia
E. M. Catarrhalis
F. S. pneumoniae
G. Legionella pneumophila
H. MSSA
I. MSSA or MRSA
J. MRSA
K. Chlamydia psittaci
L. H. influenzae
M. PCP/ P jiroveci
A

F. S. pneumoniae

32
Q

A 35 year old clown who is a specialist in bird/clown comedy is found to have an atypical pneumonia which is treated with Augmentin and Clarythromicin

All Answer Choices
A. Anaerobic infection
B. Chlamydia pneumoniae
C. M tuberculosis
D. Burkholderia cepacia
E. M. Catarrhalis
F. S. pneumoniae
G. Legionella pneumophila
H. MSSA
I. MSSA or MRSA
J. MRSA
K. Chlamydia psittaci
L. H. influenzae
M. PCP/ P jiroveci
A

K. Chlamydia psittaci

Pathology blackboard questions (5 decks)

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