Microbiology Flashcards

1
Q

What are some examples of sterile sites in the body?

A
Ureter
CSF
Peritoneal/ pericardial/ pleural/ synovial fluid
Bone marrow
Blood
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2
Q

How do you differentiate between staph and strep (both G+ve cocci)?

A

Catalase test

Staph is catalase +ve
StrEp is catalase nEgative

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3
Q

Give 3 infections caused by staph aureus

A
Infective endocarditis
Wound infections
Abscesses
Osteomyelitis
Toxic shock syndrome
Pneumonia
Scalded skin syndrome
Food poisoning - v short incubation period, 3 hrs
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4
Q

Where does staph aureus exist normally in the body?

A

Skin and nose

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5
Q

Give 2 features of staph epidermidis

A

Prosthesis infections

Forms biofilms

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6
Q

Give 2 features of staph saprophyticus

A

Urinary tract infections

Produces urease

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7
Q

Where is strep pneumoniae found?

What infection is it most associated with?

A

Throat and larynx

Community acquired pneumonia

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8
Q

Which patients might be predisposed to strep infections?

A

Bronchiectasis
Asplenia
Primary ciliary dyskinesia
Hypogammaglobulinaemia

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9
Q

Where is strep viridans found?

What can it cause?

A

Found in mouth (IE dental risk in immunocompromised)
Causes deep organ abscesses (brain, liver)
Will grow on optician

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10
Q

What type of bacteria is Corneobacter Diptheriae?

A

G+ve bacilli

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11
Q

What type of bacteria is:

1) Neisseria meningitides
2) Listeria monocytogenes
3) Legionella pneumophilia

A

1) G-ve cocci
2) G+ve bacilli (causes meningitis in v young/old/immunosup)
3) G-ve bacillus

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12
Q

Give 2 examples of lactose fermenting G-ve bacilli

A

E coli
Klebsiella

Differentiate with CLED agar

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13
Q

Give 2 examples of non-lactose fermenting G-ve bacilli

A

Salmonella
Shigella

Differentiate on XLD agar - salmonella turns black, shigella stays red (has no H antigen)

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14
Q

Why do G-ve bacteria stain pink?

A

Lipopolysaccharide (endotoxin)

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15
Q

Give 3 types of pathogenic E coli

A
Entero-haemorrhagic
Urogenic (UPEC)
E coli O157
ETEC (travellers diarrhoea)
Enteroinvasive (bloody diarrhoea and dysentry)
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16
Q

What is the virulence factor for shigella?

What can it cause if it enters the blood?

A

Shiga toxin

Haemolytic uraemia syndrome - can lead to kidney failure

17
Q

What is the name of the bacteria that causes typhoid?

A

Salmonella typhi

18
Q

What infection produces ‘rice water stool’?

What is its incubation period?

A

Cholera

Hours up to 5 days

19
Q

What is the most common cause of pneumonia in COPD patients?

A

Haemophilus influenza