Microbiology Flashcards
pts with streptococcus gallolyticus induced endocarditis are at high risk for
colon cancer
staphylococcal toxic shock syndrome findings
increased ast, alt, bilirubin
reheated rice syndrome
bacillus cereus
gram p, beta hemo, coagulase p, cocci
staph aureus
staph aureus diseases names
scalded skin synd
osteomyelitis
food poisoning
toxic shock synd
pneumonia
abscess
infective endocarditis
necrotizing fasciitis
septic arthritis
staph tss results in
increased ast, alt, bilirubin
gram p, catalase p, coagulase n, urease p, cocci, novobiocin sensitive
staph epidermidis
staph epidermidis ds
infects prosthetic devices (hip implant, heart valve) and IV catheters (biofilm producing)
gram p, catalase p, coag n, urease p, cocci, novobiocin resistant
staph saprophyticus
staph saprophyticus ds
uti in young females
gram p, alpha hemo, diplococci, optochin sensitive, bile soluble
strep pneumoniae
strep pneumoniae diseases
MOPS
meningitis
otitis media
pneumonia
sinusitis
gram p, alpha hemo, cocci, optochin res, bile insoluble
strep viridans
strep viridans ds
inf endocarditis in pts with damaged heart valves
dental caries
gram p, cocci, bacitracin sens, beta hemo, pyr pos
strep pyogenes
strep pyogenes diseases
pyogenic- pharyngitis, cellulitis, impetigo
toxigenic- scarlet fever, tss, necrotizing fasciitis
immunologic- rheumatic fever, glomerulonephritis
scarlet fever symp
sandpaper like rash sparing palms and soles, strawberry tongue
gram p cocci, bacitracin res, beta hemo
strep agalactiae
strep agalactiae ds
pneumonia, meningitis, sepsis mainly in babies
staph aureus rx
penicillin, vancomycin
staph epidermidis rx
vancomycin
strep pneumoniae rx
macrolides
ceftriaxone
strep pyogenes rx
penicillin
strep agalactiae rx
intrapartum penicillin (ampicillin)
strep gallolyticus ds
bacteremia, inf endocarditis, increased incidence of colon cancer
enterococci ds
uti
bti
inf endocarditis
gram p cocci, catalase n, pyr pos, non hemo
enterococcus
enterococci medium
6.5% nacl and bile
enterococcus rx
ampicillin, linezolid, tigecycline
gram p, spore forming rods, medusa head colonies
bacillus anthracis
bacillus anthracis toxins
anthrax toxin
lethal factor (- map kinase)
edema factor (inc cAMP)
bacillus anthracis ds
cutaneous anthrax
pulmonary anthrax
cutaneous anthrax
ulcer with black eschar, may progress to bacteremia and death
pulmonary anthrax
potential bioweapon
flu like symp
progresses to pulm hemorrhage, mediastinitis (XRAY shows widened mediastinum)
pulm anthrax other name
wool sorter ds
anthrax rx
fluoroquinolones (ciprofloxacin)
doxycycline
cut and pulm anthrax complicatn
hemorrhagic meningitis
reheated rice synd caused by
bacillus cereus
bacillus cereus toxin name
cerulide
clost difficile diseases
watery diarrhea
pseudomembrane colitis
clost diff rx
oral vancomycin
metronidazole
clost tetani toxin
tetanospasmin (- gaba and glycine from renshaw cells)
clost tetani ds
spastic paralysis
trismus (lockjaw)
risus sardonicus (raised eyebrows and open grin)
opisthotonus (spasms of spinal extensors)
clost tetani rx
metronidazole, penicillin, diazepam for spasms
clost bot toxin mech
damages snare proteins, - ach release
clost botulinum ds
floppy baby synd, 5 D’s
Diplopia
Dysarthria
Dysphagia
Dyspnea
Descending flaccid paralysis
clost bot rx
human botulinum ig
clost perfringes toxin mech
alpha toxin that causes myonecrosis
clost perfringes ds
gas gangrene, hemolysis
clost perfringes rx
penicillin
corynb dip toxin mech
exotoxin inh prot synth via adp ribosylatn of ef-2
corynb dip ds
pseudomembranous pharyngitis
lymphadenopathy (bull neck appearance)
toxin disseminatn- myocarditis, arrythmias, neuropathies
corynb dip lab diag
meatchromatic granules
elek’s test pos
corynb dip rx
antitoxin +/- erythromycin or penicillin
listeria transmission
ingestion of unpasteurized dairy products, vaginal transmission during birth
listeria motility
tumbling
listeria ds
meningitis in immunocompromised (neonates and elders)
sepsis, amnionitis and spontaneous abortion in preg females
listeria rx
ampicillin
gram p, cat p, acid fast, long branching filaments
nocardia
nocardia ds
pulm infectn in immunocompromised
can spread to cns and cause abscess
noacrdia rx
sulfonamides
gram p, cat n, non acid fast, long branching filaments
actinomyces
actinomyces ds
oral/ facial abscess that drain through sinus tracts
dental caries
pid thro iud
yellow sulphur granules
actinomyces
actinomyces rx
penicillin
snap mnemonic
sulfonamides nocardia, actinomyces penicillin
fever, night sweats, wt loss, cough
tb
mycobacterium tb ppd test
positive if current or past infectn
neg if no infectn and immunocompromised pts
false pos myc tb
bcg vaccinatn
ppd test other name
mantoux test
ghon complex
hilar nodes involvements + ghon focus on lower/middle lobes of lung
reactivatn of tb high risk in
immunocompromised
tb reactivatn lobes involved
upper
hansen ds
leprosy
resevoir of myc leprae in USA
armadillos
2 forms of leprosy
tuberculous and lepromatous
lepromatous leprosy
low cmi
leonine (lionlike facies)
th2 response
lethal
tuberculoid leprosy
high cmi
hairless plaques
th1 response
leprosy rx
lepromatous-
dapsone, rifampin, clofazimine (2-5 yrs)
tuberculoid-
dapsone, rifampin (6 months)
gram n, diplococci, metabolise glucose, no maltose acid detectn
neisseria gonorrhae
neiss gon ds
Gonorrhea
septic arthritis
pid
neonatal conjuctivitis
fitz-hugh-curtis synd
neiss gon rx
ceftriaxone, screen for chlamydia as well
if chlamydia present, then add doxycycline
gram n, gluc met p, maltose acid det pos
neiss men
neiss men ds
meningococcemia with petechial hem
waterhouse-friderichsen synd
neis men rx
ceftriaxone
neis men close contacts rx
rifampin
hem inf culture
chocolate agar that contains factor 10,5
also be grown with staph aureus
hem inf ds
haEMOPhilus
E- Epiglottitis
M- Meningitis
O- Otitis Media
P- Pneumonia
hem inf vaccine schedule
b/w 2 to 18 months of age
pref 2,4,6,15 months
hem inf rx
ceftriaxone
hem inf close contacts
rifampin
burkholderia cepacia
causes pneumonia in pts with underlying lung ds (eg. cystic fibrosis)
3 stages of bordtella infectn
catarrhal- like cold
paroxysmal- whooping cough
convalescent- 100 days chronic cough
bordtella effect on leucocytes
causes lymphocytosis
pertussis rx
macrolides
(if allergic use TMP-SMX)
brucella transmission
ingestn of contaminated animal products (eg unpasteurised milk)
brucella disease
undulant fever
night sweats
arthralgia
brucella effects
hepatomegaly
splenomegaly
lymphadenopathy
brucella rx
doxycycline, rifampin
brucella complicatn
osteomyelitis
legionella stain
gm stains poorly so use silver stain
legionella medium
charcoal yeast extract medium with iron and cysteine
legionella lab diag
elevated Ag in urine
hyponatremia
elevated transaminases
legionnaire’s ds
atypical pneumonia
unilateral and lobar
pontiac fever
mild flu like
legionella rx
macrolides, fluoroquinolones
aerobic, motile, cat p, gram n, nlf, oxi p rods
pseudomonas aeruginosa
pseudomonas ds
pneuomonia
sepsis
ecthyma gangrenosum
uris
diabetes
osteomyelitis
nocosomial
addictn (infects iv drug users)
skin infectns
ecthyma gangrenosum
produced by pseudomonas specifically in immunocomp
rx of pseudomonas
piperacillin-tzobactam, fluoroquinolones
salmonella typhi virulence factor
vi capsule
salmonella typhi vaccine available?
yes
salmonella typhi rx
ceftriaxone, fluoroquinolones
salmonella species vaccine available?
no
salmonella species except typhi reservoir
poultry, eggs
shigella ds
bloody diarrhea
yersinia enterocolitica staining
bipolar
yersinia entero ds
acute bloody diarrhea
pseudoappendicitis
reactive arthritis
lactose fermenting colonies eg
McCowkey CEEKS milk.
Citrobacter
E.coli
Enterobacter
Klebsiella
Serratia
e coli ds
cystitis and pyelonephritis (utis)
pneumonia and neonatal meningitits
septic shock
EHEC serotype
O157:H7
EHEC is like which other toxin
shiga toxin
shiga toxin triad
anemia
thrombocytopenia
acute kidney inj
(HUS)
klebsiella ds
uti (nocosomial)
lobar pneumonia