Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Second > Microbiology > Flashcards

Microbiology Flashcards

1
Q

What penicillin G cover and this drug is weak in what وسط؟

A

Against everything G+ cooci and bacilli or G- cocci anaerobic bacteria spirochetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Amino-penicillin

A

Every drug that contain Am in the start of the word

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Carboxy-penicillin

A

Every word that contain car

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ureidopenicillins

A

Azlocillin
Piperacillin
Mezloccillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Semisynthetic with anti-beta lactamase activity

A

Oxacillin
Cloxacillin
Diclaxacillin
Narfcillin
Methicillin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Combination between penicillin and beta lactamase

A

Ampicillin+sulbactam=unasyn
Amoxicillin+clavulanic acid = augmentin
Titracillin+clavulanic acid=timentin
Piperacillin+tazobactam=tazocin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cephalosporin generation 1

A

Narrow spectrum G+ve
Cefazolin IV
cephalexin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cephalosporin generation two

A

Expanded spectrum G+ve and G-ve
Cefuroxime
Cefuroxime axetil oral
Cefoxitine against anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cephalosporin generation three

A

Less activity G+ve and more G-ve
Cefotaxime
Cefotriaxone
Cefixime oral
Ceftazidime anti pseudomonal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cephalosporin fourth generation

A

Broad spectrum
Cefepime-parenteral
Effective against pseudomonas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Inhibition of cell membrane synthesis

A

Polymyxin E narrow spectrum against multidrug resistant G- bacilli
Polymyxin B
Daptomycin- not used in respiratory infections (inactivated by surfactant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Antimicrobial wich bind to 30s subunit

A

Aminoglycosides
Bactericidal (bind irreversibly) and given IV or topically and anti-pseudomonal and broad spectrum and ineffective against anaerobes, synergy+ beta lactams
Agents:
Any drug that end’s with cin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Antimicrobial wich bind to 30s subunit tetracycline

A

-Broad Spectrum
-Intracellular bacteria (chlamydias, reckettsias), Mycoplasma
-Members
Tetracycline, minocycline, doxycycline.
Side effect do painting and secondary infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Antimicrobial wich bind to 30s subunit, spectinomycin

A

Bacteriostatic, reversible bond eith mRNA interaction with 30s ribosome.
Spectrum of activity: penicillin-R, N.gonorrhoeaea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Antimicrobial wich bind to 50s ribosomal subunit. Chloramphenicol

A

Bacteriostatic
Side effects BM suppression= grey baby syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Antimicrobial wich bind to 50s ribosomal subunit. Macrolides

A

Spectrum of activity
G+ bacteria in penicillin allergy
Chlamydias
Mycoplasmas
Legionella
Treponema pallidum
Agents:
Every drug that ends with thromycin

17
Q

Antibacterials wich interfere with elongation factors fusidic acid

A

Inhibits release of EF-G from EFG/GDP complex

18
Q

Inhibitors of nuclec acid synthesis

A

Inhibitors of RNA synthesis
Rifampin, rifamycin, rifampicin
Broad but used most commonly in Rx of TB
Rx= therapy

19
Q

Inhibitors of DNA synthesis Quinolones (fluoroquinolones)

A

Ciprofloxacin orally, ofloxacin, levofloxacin, norfloxacin, moxifloxacin.
S/E tendon rupture (googleit)
Broad spectrum and anti pseudomonal

20
Q

Anti metabolic antibacterial sulfonamide

A

Analogue of PABA p-aminobenzoic acid
competitive inhibitors of dihydropteroic acid (second step of synthesis folic acid)
Used in UTI and nocardia infections

21
Q

Anti metabolic antibacterial Trimethoprine

A

Inhibibits formation of tetrahydrofolic acid
Same uses as sulfonamide

22
Q

Anti metabolic antibacterial co-trimoxazole

A

Combination of sulfonamide and trimethoprim oral

23
Q

Antimycobacterial agents

A

In TB , 4 routinely prescribed drug
Isoniazid
Rifampin
Pyrazinamide
Pyrazinamide
Ethambutol

24
Q

S/E

A

Allergy and anaphylactic shock
Toxicity
Chloramphenicol-> aplastic anemia
Streptomycin -> auditory nerve damage and deafness
Superinfections, Ex
Clostridium difficile that causes
ADD: antibiotics associated diarrhea
PMC: pesudomembranous coitits

25
Q

Drug resistance, superbugs that should be reported to infection control committees

A

MRSA ,MRSE,VISA
VRSA, VRE, MDR-TB, XDR-TB
Extended spectrum beta lactamases
Carbapenemase-producing enterobacteriaceae

26
Q

Acquired resistance

A

Chromosome mutations, change the protein binding site, no binding of agent
Chromosomes mutation, cange membrane permeability, no entry of agent
Acquisition of new gene (lec 2micro) production of new bacterial E, no effectiveness of the agent
Acquisition of new gene (lec2micro), production of bacterial multidrug resistance

27
Q

Antiviral drug

A

HSV: acyclovir, ganiciclovir
Respiratory viruses: amantadine, ribavirin
HIV: zidovudine

28
Q

Anti fungal drugs

A

AmphotericinB is the DOC for systemic mycoses

Griseofulvin: binds tubulin and inhibits mitosis

Second (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions