Microbe Persistence In Host Cells

Question 1

Colonization

Answer 1

The growth of microbes on epithelial surfaces such as the skin and mucous membranes

Question 2

Peplomers

Answer 2

Specialized receptors on viral surfaces (glycoprotein spikes)

Question 3

Establishment

Answer 3

Increase in numbers; large population size

Question 4

Generation time

Answer 4

Time it takes for one cell to divide via binary fission

Question 5

Escape phagocytosis by:

Answer 5

• Production of leukocidins

- Survive engulfment through protective layers (slime layer & capsule)

Question 6

Evade host defense

Answer 6

Viruses remain latent

Question 7

Latency

Answer 7

Periodic reactivation of microbe

Question 8

Viruses damage host by

Answer 8

1. Cell death (Necrosis & Apoptosis)
2. Inhibit cell growth
3. Inhibit metabolism & cell function

Question 9

Cytotoxic(ity)

Answer 9

Any substance or agent that is toxic to the cell; often results in cell death

Question 10

Cytolysis

Answer 10

Death of a cell by lysis; often a result of osmotic changes

Question 11

Cytopathic/Cytopathogenic

Answer 11

Damage to cells