Micro Systems Flashcards
Normal Dominant Flora of Skin
Staphylococcus epidermidis
Normal Dominant Flora of Nose
Staph epidermidis. Colonies by Staph aureus
Normal Dominant Flora of Oropharynx
Viridans Group Strep
Normal Dominant Flora of Dental plaques
Streptococcus mutans
Normal Dominant Flora of Colon
Bacteroides fragilis (more) E. coli (less)
Normal Dominant Flora of Vagina
Lactobacillus
Colonies by E coli and GBS
Neonates delivered by Cesarean section re flora?
They have no flora but are rapidly colonized after birth
Staph aureus and B cereus food poisoning course
Starts quickly and ends quickly
Contaminated seafood
Vibrio parahaemolyticus and V vulnificus (can cause wound infection from contact with contaminated water or shellfish)
Reheated rice
“be serious”
B cereus
Meats, Mayonnaise, Custard
S aureus
Reheated meat dishes leading to watery diarrhea
Clostridium perfringens
Improperly canned foods (bulging cans)
Clostridium botulinum
Undercooked meat
E coli O157:H7
Poultry, meat, eggs
Salmonella
Bugs that can mimic appendicitis
Yersinia enterocolitica causes mesenteric adenitis
Nontyphoidal Salmonella
Campylobacter jejuni
Causes of Bloody Diarrhea with signs
Campylobacter: Comma or S shaped, grows at 42
Salmonella: Lac-, Flagella
Shigella: Lac-, low ID50
EHEC, EIEC
Yersinia enterocolitica: Daycare outbreaks, pseudoappendicitis
Entamoeba histolytica
Causes of Watery Diarrhea
Enterotoxigenic E coli: Traveler’s, ST and LT toxin
V Cholerae: comma-shaped, rice-water
C difficile: bloody w/ pseudomembranous colitis
C perfringens: also gas gangrene
Protazoa: Giardia, Cryptosporidium (in immunocompromised)
Rotavirus, Norovirus
Pneumonia in neonate (less than 4 weeks)
GBS, E coli
Pneumonia in children (4 weeks to 18 years)
“Runts May Cough Chunky Sputum”
RSV, Mycoplasma, C. pneumoniae (school age), Chlamydia trachomatis (infant to 3 years), Streptococcus pneumoniae
Pneumonia in adults (18 years to 40 years)
Mycoplasma, C pneumoniae, S pneumoniae
Pneumonia in adults (40 years to 65 years)
S pneumoniae, H influenzae, Anaerobes, Viruses, Mycoplasma
Pneumonia in elderly
S pneumoniae, Influenza, Anaerobes, H influenzae, H influenzae, Gram- rods
Special Nosocomial Infections
Staph, Enteric Gram negative Rods
Special Immunocompromised infections
Staphylococcus, Enteric Gram- rods, Fungi, Viruses, Pneumocystis jirovecii - w/ HIV
Special infections with aspiration
Anaerobes
Special infections w/ EtOH and IV drug users
S pneumoniae, Klebsiella, Staph
Special infections in CF
Pseudomonas, S aureus, S pneumoniae
Special infections in Post-Viral pt
Staph, H influenzae, S pneumoniae
Bugs that cause atypical pneumonia
Mycoplasma, Legionella, Chlamydia
Meningitis in a newborn (0 to 6 months)
GBS, E coli, Listeria
Meningitis in a child (6 months to 6 years)
PathoPhys
Presentation
Streptococcus pneumoniae Neisseria meningitidis Enteroviruses Haemophilus influenzae type B Polio Last 2 in non immunized children Microbe colonizes nasopharynx leading to myalgias and paralysis
Meningitis in a adults (6 years to 60 years)
S pneumoniae
N meningitidis (#1 in teens)
Enteroviruses
HSV
Meningitis in elderly (60+)
S pneumoniae
Gram- rods
Listeria
Meningitis Treatment
Ceftiazone and Vancomycin empirically
Add ampicillin if Listeria is suspected
Viral causes of meningitis
Enterovirus (esp coxsackievirus), HSV2 (HSV1 = encephalitis), HIV, West Nile Virus, VZV
Meningitis in HIV pt
Cryptococcus, CMV, toxoplasmosis (brain abscess), JC virus (PML)
Recent changes in H influenzae meningitis
Decreased with introduction of conjugate H influenzae vaccine in last 10-15 years.
Todays cases are in un-immunized children
CSF findings in Bacterial meningitis Opening pressure Cell type Protein Sugar
Opening pressure ↑
PMNs
Protein ↑
Sugar ↓
CSF findings in Viral meningitis Opening pressure Cell type Protein Sugar
Opening pressure Normal or ↑
Lymphocytes
Protein is Normal or ↑
Sugar is Normal
CSF findings in Fungal/TB meningitis Opening pressure Cell type Protein Sugar
Opening pressure ↑
Lymphocytes
Protein is Normal or ↑
Sugar ↓
Osteomyelitis w/ nothing else
S aureus
Osteomyelitis in sexually active individual
Neisseria gonorrhoeae (rare), septic arthritis more common
Osteomyelitis in diabetic or IV drug user
Pseudomonas aeruginosa, Serratia
Osteomyelitis in Sickle cell disease
Salmonella