Micro Lecture 3/4 Flashcards
How does chlamydia cause blindness
Damage is due to scraping of the cornea, not the actual infection
Does the eye have pain or visual loss with keratitis
Yes
Presentation of ocular gonorrhea in an adult
Fountain of puss out of the eye after wash
Causative agents of onchocerciasis
Onchocerciasis volvulus - filaria transmitted via black fly; worm dies and releases wolbachia spp
What type of conjunctivitis is associated with URI
Viral conjunctivitis
Inflammation of cornea
Keratitis
Disease process associated with pseudodendritic keratitis
Herpes zoster/shingles/VZV
Most common infections conjunctivitis
Adenovirus
Body sites affected by chlamydia
Mucosal epithelial cells
- urethra
- eye
- lung
What chlamydia serotypes are responsible for majority of blindness around the world (trachoma)
- and what are they transmitted by
A, B and C
- transmitted by fly
Inflammation of the conj
Conjunctivitis
Does the eye have pain or visual loss in conjunctivitis
Neither
Commonality between a canthal ONeal keratitis and bacterial keratitis
Both common in CL patients
2 key clinical observations of loa loa
- calabar swelling
- worm in the eye
What is tzanck prep used for
To rule out herpes
Causative agent of Loa Loa
African eye worm
- Fly ingests microfilariae and bite humans
Does chlamydia have a cell wall
No
What is a dendritic keratitis
- what causes it?
has a dendritic branching pattern
- HSV
- cold sore of the eye*
Which is diagnostic for chlamydia, elementary or reticulate bodies
Reticulate bodies
-non infectious
Symptoms of viral conjunctivitis
- Follicular (clear domes)
- Watery/mucoid discharge
- usually unilateral
Body sites affected by chalmydophila
Respiratory sites
- lungs
Which presents with a worm in the eye, loa loa or onchocerciasis
Loa loa
Most common cause of infectious conjunctivitis
Adenovirus
Most common source of bacterial keratitis
Sta. Aureus and Ps. Aerouginosa
Potential consequences of failure to treat gonorrhea
- Corneal rupture/perforation
- ulcerative keratitis
- visual loss
- ***treat quickly
What type of stain is a tzanck cell
WG stain
- look for multinucleated cells
Top 2 eye-related warning signs that require immediate action
Ocular pain and vision loss
Leading cause of blindness
Trachoma
What is the gram stain description for pseudomonas aerouginosa
Gram - rod
- also grows on blood and chocolate
- non lactose fermenter (colorless on macconkey)
- oxidase positive
Cold sore on the eye
HSV keratitis
Which form of chlamydia is infectious, elementary or reticulate bodies
Elementary bodies
Why aren’t all viral infections of the eye treated equally?
- Most will resolve with little/no Tx
- viruses like HSV need to be treated aggressively to prevent HSV keratitis
Symptoms of bacterial conjunctivitis
- Papillary or nonspecific (cobblestone)
- mucopurulent (thick) discharge
- probably bilateral
What is the gram stain description for staph aureus
Gram + cocci (cat and coag + too)
Most common bacterial conjunctivitis
C. Trachomatis
Commonly seen in fungal keratitis
Aspergillus (elevated lesion)
Which can lead to blindness, loa loa or onchocerciasis
Onchocerciasis
