micro 4 Flashcards
Part of body with highest bacterial diversity
colon
10^10 - 10^13
pH of small intestine
6.5 - 7.5
pH of colon
5 - 7
oxygen content in small intestine, stomach and colon
small intestine - decreased oxygen
stomach - oxygen present
colon - anaerobic
bacteria in small intestine
facultative anaerobes
streptococcus
lactobacillus
enterobacteriaceae
bacteria in stomach
mainly streptococcus and lactobacillus
bacteria in colon
particularly anaerobes
clostridia
bacteriodes
bifidobacterium
How do bacteria contribute to metabolism?
provides nutrients humans can't produce normally breakdown of non-digestible substrates (dietary fibre and intestinal mucus) production of short chain FAs (acetate, propionate and butyrate) amino acid metabolism (tryptophan) vitamin production (B10, PABA)
What bacteria breaks down tryptophan?
E coli
What breaks down tryptophan?
tryptophanse
Microbes derived from maternal skin in cesarean
staphylococcus
propionibacterium
How do artificial sweeteners effect the gut microbiome?
cause overgrowth of E coli and proteobacteria
increase fecal pH
decrease bacteroides and clostridia
-> increase glucose intolerance