micro Flashcards

1
Q

neisseria gonorrhoeae

A

character: Gr -, diplococci, glucose oxidizer
disease: gonococcal joint infection (local & dissemination)
virulence factors: opa adhesins, IgA1 protease, blebbing
found: mucosa
drug: ceftriaxone

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2
Q

Borrelia Burgdorferi

A
Character: Gr -, spirochete, axial filaments
disease: lyme disease
virulence factors: biofilms and blebbing
found: mice reservoir
drug
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3
Q

kingella kingae

A

Character: Gr -, coccobacilli, B-hemolytic, oxidase +
disease: septic arthritis, osteomyelitis, <4yrs old
virulence: pili adhesins
found: puncture wound (oropahrynx)
drug:

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4
Q

staph aureus

A

character: Gr+, cocci in clusters, coagulase+, beta-hemolysis
disease: pyomyositis and osteomyeolitis
virulence: protein A, exotoxins
found:
drug:

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5
Q

pasteurella multicida

A

character: capsule
disease: cellulitis and osteomyelitis
virulence:
found:
drug:

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6
Q

nocardia (actinomyces)

A
Character:
disease:
virulence:
found:
drug:
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7
Q

Haemophilus Influenza

A
Character:
disease:
virulence:
found:
drug: any cephlosporin
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8
Q

bartonella Henselae

A
character:
disease:
virulence:
found:
drug:
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9
Q

clostridium perfringens

A
character:
disease:
virulence:
found:
drug:
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10
Q

actinomyces israelii

A
character:
disease:
virulence:
found:
drug:
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11
Q

Eikenella Corrodens

A
character:
disease:
virulence:
found:
drug:
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12
Q

brucella

A
character:
disease:
virulence:
found:
drug:
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13
Q

streptococcus pyogenes

A
character: 
disease:
virulence:
found:
drug:
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14
Q

pseudomonas aeruginosa

A
character:
disease:
virulence:
found:
drug: pip-tazo
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15
Q

staph epidermidis

A
character:
disease:
virulence:
found:
drug:
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16
Q

human Papilloma virus

A

Family: papillomaviridae
character: circular dsDNA, no envelope, nuclear replication
cancer:cervical carncinoma, penile and anal carcinoma (sexual)
mechanism of oncogenesis: E7&E6 block pRb &p53, respectively

17
Q

Epson Barr Virus

A

Family: herpesvirdae
character: large, linear dsDNA; enveloped; nuclear replication
cancer: Burkitt & Hodgkin’s lymphoma, nasopharyngeal carcinoma (saliva)
mechanism of oncogenesis: c-myc translocation (Burkitt lymphoma) & latency genes

18
Q

Human herpes virus, HHV-8

A

family: Herpesviridae
character: large, linear, dsDNA; enveloped; nuclear replication
cancer: Kaposi sarcoma, primary effusion lymphoma (sexual)
mechanism of oncogenesis: several human homologues (lytic and latent genes)

19
Q

Human T-lymphotropic virus 1

A

family: Retroviridae
character: linear, diploid ssRNA; enveloped; nuclear replication
cancer: Adult T-cell leukemia/lymphoma (sexual, IDU, breastfeeding)
mechanism of oncogenesis: Tax regulation of cellular signaling (eg. IL-2 & IL-2R)