micro

Question 1

neisseria gonorrhoeae

Answer 1

character: Gr -, diplococci, glucose oxidizer
disease: gonococcal joint infection (local & dissemination)
virulence factors: opa adhesins, IgA1 protease, blebbing
found: mucosa
drug: ceftriaxone

Question 2

Borrelia Burgdorferi

Answer 2

Character: Gr -, spirochete, axial filaments
disease: lyme disease
virulence factors: biofilms and blebbing
found: mice reservoir
drug

Question 3

kingella kingae

Answer 3

Character: Gr -, coccobacilli, B-hemolytic, oxidase +
disease: septic arthritis, osteomyelitis, <4yrs old
virulence: pili adhesins
found: puncture wound (oropahrynx)
drug:

Question 4

staph aureus

Answer 4

character: Gr+, cocci in clusters, coagulase+, beta-hemolysis
disease: pyomyositis and osteomyeolitis
virulence: protein A, exotoxins
found:
drug:

Question 5

pasteurella multicida

Answer 5

character: capsule
disease: cellulitis and osteomyelitis
virulence:
found:
drug:

Question 6

nocardia (actinomyces)

Answer 6

Character:
disease:
virulence:
found:
drug:

Question 7

Haemophilus Influenza

Answer 7

Character:
disease:
virulence:
found:
drug: any cephlosporin

Question 8

bartonella Henselae

Answer 8

character:
disease:
virulence:
found:
drug:

Question 9

clostridium perfringens

Answer 9

character:
disease:
virulence:
found:
drug:

Question 10

actinomyces israelii

Answer 10

character:
disease:
virulence:
found:
drug:

Question 11

Eikenella Corrodens

Answer 11

character:
disease:
virulence:
found:
drug:

Question 12

brucella

Answer 12

character:
disease:
virulence:
found:
drug:

Question 13

streptococcus pyogenes

Answer 13

character: 
disease:
virulence:
found:
drug:

Question 14

pseudomonas aeruginosa

Answer 14

character:
disease:
virulence:
found:
drug: pip-tazo

Question 15

staph epidermidis

Answer 15

character:
disease:
virulence:
found:
drug:

Question 16

human Papilloma virus

Answer 16

Family: papillomaviridae
character: circular dsDNA, no envelope, nuclear replication
cancer:cervical carncinoma, penile and anal carcinoma (sexual)
mechanism of oncogenesis: E7&E6 block pRb &p53, respectively

Question 17

Epson Barr Virus

Answer 17

Family: herpesvirdae
character: large, linear dsDNA; enveloped; nuclear replication
cancer: Burkitt & Hodgkin’s lymphoma, nasopharyngeal carcinoma (saliva)
mechanism of oncogenesis: c-myc translocation (Burkitt lymphoma) & latency genes

Question 18

Human herpes virus, HHV-8

Answer 18

family: Herpesviridae
character: large, linear, dsDNA; enveloped; nuclear replication
cancer: Kaposi sarcoma, primary effusion lymphoma (sexual)
mechanism of oncogenesis: several human homologues (lytic and latent genes)

Question 19

Human T-lymphotropic virus 1

Answer 19

family: Retroviridae
character: linear, diploid ssRNA; enveloped; nuclear replication
cancer: Adult T-cell leukemia/lymphoma (sexual, IDU, breastfeeding)
mechanism of oncogenesis: Tax regulation of cellular signaling (eg. IL-2 & IL-2R)