Micro 2: Fungal Infections, PUO, Fever in Returning Traveller, Herpes infection, Zoonoses and Viral Hepatitis Flashcards
How do we differentiate causes of deranged liver enzymes?
Cholestatic or Hepatic
What is expected ALT for Hepatitis?
In the 1000s
What viruses to think of in a 28 weeks old pregnant mother
HIV HEP
CMV
many more
What % of pregnancies are affected by CMV?
If pro,army infection in pregnancy
1-5%
How to check for viruses in a patient?
Send for serology
How to check if someone has had chicken pox before?
Varicella Zoster immunoglobulin
Woman and partner both HIV+ve, want to have a baby.
What is risk of mother-child transmission if she is not taking ART?
20-45% depending on how long they breastfeed.
In Africa recommend breastfeed, in UK don’t.
Big risk of tenofovir?
Renal failure - must be monitored.
What is specifically measured in antenatal hep B screening?
Hep B DNA
Positive or negative if over a certain amount
What risks do cats pose to the unborn child?
Toxoplasmosis
What does cheesy pizza retinitis point to?
Toxoplasmosis
What does toxoplasmosis cause congenitally?
Neurocognitive damage
Hydrocephalus
Blindness
Spot diagnosis from family photograph
Retinoblastoma
Photo of children with biiiig swollen cheeks and jaw bone
Big complication
Mumps
Orchitis —> infertitility
34 yo female, fever, brief seizure during exam, no rash no neck stiffness, has confusion
Dx and Mx? Key Ix?
Encephalitis (most likely viral)
Lumbar puncture —> send CSF for HSV PCR
A —> E approach
Acyclovir (only useful for HSV)
Ceftriaxone (to cover for bacterial encephalitis)
(Confusion most common, seizure second most common)
