methylphenidate Flashcards

1
Q

brand name

A

Concerta

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2
Q

FDA approved for…

A

ADHD, narcolepsy

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3
Q

Off label use for…

A

Treatment resistant depression

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4
Q

Mechanism of action

A

Norepinephrine and dopamine reuptake inhibitors.

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5
Q

Parts of the brain where it works

A
  1. Dorsolateral prefrontal cortex
  2. Basal ganglia
  3. Medial prefrontal cortex, hypothalamus
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6
Q

Enhancing dopamine and norepi in the dorsolateral prefrontal cortex…

A

Improves attention, concentration, executive function, and wakefulness

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7
Q

Enhancing dopamine in the basal ganglia

A

improves hyperactivity symptoms

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