Methods Of Modifying Behaviour - Antipsychotic Drugs

Question 1

Typical antipsychotics

Answer 1

• 1st gen of antipsychotic drugs.
• Dopamine antagonist

Question 2

Atypical antipsychotics

Answer 2

• 2nd gen
• improve the effectiveness of reducing positive symptoms and reduce side effects
• works on dopamine receptors

Question 3

Clozapine

Answer 3

• Atypical
• binds to dopamine receptors but also acts with serotonin and glutamate receptors.
• sometimes diagnosed to patients with low mood/depression as it increases mood
• daily dosage of 300-400mg a day
  -patients were dying from a blood condition called agranulocytosis

Question 4

Chlorpromazine

Answer 4

• Typical (1st gen drug)
• dopamine antagonist blocks receptors on the post synaptic neuron which stops the transmission of dopamine
• reduces positive symptoms like hallucinations and delusions
• up to 100mg (smaller in beginning )
• movement problems can be developed (tardive dyskinesia), agitated weight gain and itchy skin.

Question 5

Risperidone

Answer 5

• Atypical
• binds to dopamine and serotonin receptors but is stronger than clozapine so Doreen’s require high dosages
• common dosage of 4-8mg or 12mg max
• very few side effects