Methods Of Localization GW Flashcards
Phagocytosis
Removal of foreign matter by physical entrapment
Sulfur colloid
Phagocytosis
Capillary blockade
Mechanical obstruction of capillaries or pre capillary arterioles in the lungs
Active transport
Cellular metabolism concentrates in RP in organ or tissue
Simple diffusion
Movement of RP from area of higher concentration to area of lower concentration
Cell sequestration
Removal of damaged or old RBCs from the circulation by the spleen; uptake of WBCs in infection sites
Compartments localization
Introduction of RP into we’ll definitely body compartment where it remains for an extended period of time
Antigen-antibody complex formation
Radiolabeled antibody binds to tumor associated antigen
MAA
Capillary blockade
I123
Active transport
Breakdown of BBB allowing water soluble RP to penetrate brain in area of affected tissue
Simple diffusion
Cr51 RBCs taken up by spleen
In111 WBCs site of infection
Cell sequestration
99mTc DTPA aerosol; 133Xe
Compartmental localization
Using tumor specific labeled antibodies to detect cancer or stage therapy
Antigen-antibody complex formation