Methods Flashcards
Amnesia is an impairment of…
Declarative and episodic memory
Electrophysiology is…
Micro-electrodes are implanted into the brain to record activity from electrodes
DBS surgery involves inserting an electrode into the…
Subthalamic nucleus of the basal ganglia. This is connected to a battery and placed in chest. STN is stimulated to control motor symptoms
Excessive beta activity in Parkinson’s…
Leads to the ability for the beta to put a brake on movement to be too powerful
PET is done by…
Inject with glucose, water or inhale oxygen with tracers in them (radioactive isotope). Sensors in scanner detect radioactivity. Glucose/O2 carried to bloodstream and more active brain areas get more tracers and emits gamma. This is picked up in PET.
The PET sensors detect radiation because the substance…
Decays
Sharp et al (2010) PET found…
Left angular gyrus is more active for difficult semantic tasks. (ppts had a PET scan during)
PET pros
Non-invasive
See brain activity as task is performed
Use radioactive variants of drugs to see activity on brain
PET cons
Poor temporal resolution Cannot see fine tuned aspects Expensive Radioactivity not safe Scans averaged together=poor resolution
MRI involves…
Protons act as magnets, applies strong magnetic field to brain, magnets interact, different tissues create different magnetic field
Villarreal et al. (2002) MRI found…
More stress from PTSD means a smaller hippocampus (poor memory) Bremner (1999) said this was due to neurotoxic effect of stress hormones
MRI pros
Non-invasive
Good resolution
MRI cons
Images near brain cavities difficult, mag. field distorted
Noisy and claustrophobic=anxiety
fMRI involves…
Same as MRI but images of brain function, not structure. Oxygenated and non blood have different mag. properties. Working areas of brain need more O2 blood
Grill-Spector, Knouf & Kanwisher (2004)
Found when shown faces, ppts’ Fusiform area and lateral occipital cortex activated. Brain has areas for face recognition