Methanol

Question 1

Methanol: Risk assessment

Answer 1

> 0.5ml/kg potentially lethal

Question 2

Methanol: Life Threats

Answer 2

CNS: sz/ depression/ cerebral edema
Blindness
Metabolic acidosis
hypoglycaemia
Long term:
Extrapyramidal movement disorder

Question 3

Methanol: adjunct treatment

Answer 3

Folinic acid: 2mg/kg q 6h

till poisoning treated

Question 4

Methanol: Antidote

Answer 4

ETOH aim level 22- 44 mmol/L
PO/NG: 
-load: 1.8ml/kg 43% (3x40ml shots vodka)
-main: 0.2-0.4 ml/kg/hr
IV:
-load: 8mls/kg 10%
- main: 1-2 mls/kg/hr

Question 5

Methanol Enhanced Eliminations

Answer 5

Dialysis indication:
-lrg ingestion
-toxicity: blindness/ renal failure
-Biochemical
pH  10
Methanol level > 16 mmol/L
AIM:
normal pH
Osmolar gap < 6

Question 6

Methanol Disposition

Answer 6

Check VBG q4 hr for 24hrs

CTB: basal ganglia injury with permanent neurological sequelae