Metastases Flashcards

1
Q

What tumours commonly cause bone mets?

A

Prostate
Breast
Lung

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Most common sites of bone mets? Detection method?

A
Spine
Pelvis
Ribs
Skull
Long bones

Isotope bone scan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are features of bony mets?

A

Pathological fractures
Bone pain
Hypercalcaemia
Raised ALP

FAPH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What Ix for metastatic disease of unknown primary?

A
FBC
U&E
LFT
Calcium
Urinalysis
LDH

CXR
CT CAP
AFP and hCG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What Ix if lytic bone lesions? Men? Women with peritoneal malignancy of ascites? Germ cell tumour?

A

Myeloma screen (if lytic bone lesions)
Endoscopy (directed towards symptoms)
PSA (men)
CA 125 (women with peritoneal malignancy or ascites)
Testicular US (in men with germ cell tumours)
Mammography (in women with clinical or pathological features compatible with breast cancer)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is PET? Uses?

A

Nuclear imaging which uses fluorodeoxyglucose as radiotracer
Allows 3D image of metabolic activity generated using glucose uptake
Combined with CT to see where metabolically active lesions are

Evaluating primary and possible mets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Presentation of metastatic spinal cord compression? Ix?

A

New onset nocturnal back pain

MRI spine within 24 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly