Metabolismo De La Glucosa Y Lipidos Flashcards

1
Q

Inhibidor del complejo 1 de la cadena respiratoria:
Disminuye el ATP y aumenta AMP

A

Metformina

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2
Q

RAM de la metformina

A

Gastrointestinales
Disminuye vitamina B12
Acidosis lactica

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3
Q

Agonista del receptor SUR
(Sulfunilurea)

A

Glibenclamida

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4
Q

Despolorizacion de la celula B pancreatica y aumenta insulina

A

Glibenclamida

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5
Q

RAM de la glibenclamida

A

Hipoglucimiantes

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6
Q

Agonista del receptor PPARy

A

Pioglitazona

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7
Q

Inhibidor de la dipeptidil peptidasa-4 (DPP-4)
Aumenta la GLP-1

A

SAXAGLIPTINA

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8
Q

CYP de la saxagliptina

A

CYP3A4

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9
Q

Agonista de GLP-1

A

EXENATIDA

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10
Q

Inhibidor del cotransportador sodio-glucosa tipo 2 en el tubulo contorneado proximal:

A

DAPAGLIFLOZINA

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11
Q

RAM de la Dapagliflozina

A

Fracturas
Altera Vitamina D y PTH
Glucosuria

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12
Q

Activadores del receptor de insulina

A

INSULINAS

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13
Q

RAM de la insulina

A

Hipoglucemia

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14
Q

Inhibidor competitivo de la enzima HMG - CoA reductasa:

A

PRAVASTATINA, ATORVASTATINA y simvastatina

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15
Q

Indicaciones de la atorvastatina y pravastatina

A

Dislipidemias

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16
Q

RAM de las dislipedimas

A

Hepatotoxicidad
Miopatia
Rabdiomiolisis

17
Q

Contraindicaciones De Pravastatina y Atorvastatina

A

Embarazo e hipersensibilidad

18
Q

Contraindicaciones de la metformina

A

Acidosis metabolica
Enfermedad renal cronica

19
Q

Contraindicaciones de la glibenclamida

A

Tx de DM1 y embarazo

20
Q

Indicaciones dr la Dapaglifozina

A

DM2

21
Q

RAMs Saxagliptina

A

Mayor riesgi hospitalizacion por insuficiencia cardiaca

22
Q

RAMs de la exenatida

A

Gastrointestinales

23
Q

Contraindicaciones de la exenatida

A

Enfermedad renal cronica

24
Q

Contraindicaciones del pioglitazona

A

Embarazo
Insuficiencia cardiaca