Metabolism in animals

Question 1

What does glycolysis generate?

Answer 1

ATP and NADH

Question 2

What are the three irreversible reactions in glycolysis?

Answer 2

Hexokinase
Phosphofructokinase
Pyruvate Kinase

Question 3

What are the three bypasses in gluconeogenesis?

Answer 3

Pyruvate carboxylase
Fructose-1,6-biphosphatase
Glucose-6-phosphatase

Question 4

How does the first bypass, pyruvate carboxylase works?

Answer 4

pyruvate carboxylase is used to convert pyruvate from glycolysis to Oxaloacetate then Malate. The Malate will then back to Oxaloacetate. Phosphoenolpyruvate carboxykinase (PEPCK) is used to convert Oxaloacetate to phosphoenolpyruvate (PEP).

Question 5

Why is fermentation important tp keep glycolysis going?

Answer 5

Fermentation allows the conversion of NADH to NAD+, so glycolysis can have NAD+ to generates energy and NADH.

Question 6

What is the Cori cycle (lactic acid cycle)?

Answer 6

Cori cycle occurs between skeletal muscle and liver. It is a metabolic pathway in which lactate produced by anaerobic glycolysis (no oxygen) in the muscles move via the bloodstream to the liver where it is converted into blood glucose and glycogen.