Metabolism & Glycolysis

Question 1

Which process in metabolism is degradative, convergent, oxidative and produce ATP, FADH2, NADH and NADPH?

Answer 1

Catabolism

Question 2

Which process in metabolism is divergent, reductive, and uses ATP?

Answer 2

Anabolism

Question 3

Conversion of building blocks to acetyl CoA happens where?

Answer 3

Cytoplasm

Question 4

Oxidation of Acetyl CoA happens where?

Answer 4

Mitochondria

Question 5

What stimulates β-adrenergic receptors?

Answer 5

Epinephrin/norepinephrine

Question 6

What activates adenylyl cyclase?

Answer 6

Gs (αsubunit)

Question 7

Adenylyl cyclase does what?

Answer 7

catalyze the formation of cAMP

Question 8

What does cAMP do in the cell?

Answer 8

Activates PKA

Question 9

What does PKA do?

Answer 9

causes phosphorylation of cellular proteins and cause a cellular response

Question 10

What are the second messengers in the phosphoinositide system?

Answer 10

IP3, DAG, and Ca++

Question 11

What activates phospholipase C?

Answer 11

Gqα

Question 12

What cleaves PIP2 to produce two second messengers and what are they?

Answer 12

PLC and they are DAG and IP3

Question 13

What does IP3 do inside the cell?

Answer 13

It activates the ER and releases Ca++

Question 14

What does DAG activate?

Answer 14

PKC

Question 15

What does PKC do?

Answer 15

protein kinase C phosphorylates substrates proteins resulting in cellular responses

Question 16

What does PKC need for maximum energy?

Answer 16

DAG, phospholipids and Ca++

Question 17

Which transporter is in most cell types but not in the kidneys or small intestinal epithelial cells?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 17

A. GLUT 1

Question 18

Which transport is fund in neurones, placenta and the testes?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 18

C. GLUT 3

Question 19

Which transporter is found in hepatocytes, pancreatic β cells, epithelial cells of the small intestines and kidney tubules?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 19

B. GLUT 2

Question 20

Which transporter is activated and regulated by insulin?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 20

D. GLUT 4

Question 21

Which transporter is bidirectional?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 21

B. GLUT 2

Question 22

Which transporter is found in the small intestine, sperm, brain, muscle and adipocytes?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 22

E. GLUT 5

Question 23

Which transporter is only activated by fructose?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 23

E. GLUT 5

Question 24

Which transporter is found in the membrane of the endoplasmic reticulum in hepatocytes?

A.  GLUT 1
B.  GLUT 2
C.  GLUT 3
D.  GLUT 4
E.  GLUT 5
F.  GLUT 7
G. SGLUT1

Answer 24

F. GLUT 7

Question 25

What is the overall yield from 1 molecule of glucose in aerobic and anaerobic glycolysis?

Answer 25

2 ATP and 2 NADH

2 ATP

Question 26

What are the fates of pyruvate?

Answer 26

OAA, Acetyl CoA, Alanine, Lactate

Question 27

What 3 enzymes does insulin up regulate?

Answer 27

Glucokinase, PFK, pyruvate kinase