metabolism Flashcards

1
Q

glucurondiation co-substrate

A

UDP-glucuronic acid (UDPGA)

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2
Q

glucuronidation enzyme

A

UDP-glucuronyltransferase (UGT)

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3
Q

glucuronidation deconjugating enzyme

A

beta- glucuronidase

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4
Q

sulfation co-substrate

A

Phosphoadenosine- phosphosulfate (PAPS)

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5
Q

sulfation enzyme

A

SULT - sulfotransferase

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6
Q

sulfation deconjugating enzyme

A

sulfatase

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7
Q

glutathione conjugation co- substrate

A

GSH

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8
Q

glutathione conjugation enzyme

A

Glutathione S-transferase (GST)

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9
Q

amino acid conjugation co-substrate

A

glycine, glutamine, aspartic acid, serine

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10
Q

amino acid conjugation enzyme

A

N-acyltransferase

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11
Q

amino acid conjugation deconjugating enzyme

A

amidase

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12
Q

acetylation co-substrate

A

acetyl-coA

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13
Q

acetylation enzyme

A

N-acytltransferase

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14
Q

acetylation deconjugating enzyme

A

amidase

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15
Q

methylation co-substrate

A

S-adenosylmethionine (SAM)

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16
Q

methylation enzyme

A

methyltransferase

17
Q

methylation deconjugating enzyme

A

CYP catalyzed demthylation