Metabolism

Question 1

Metabolisms in the Mitochondria

Answer 1

Fatty Acid Oxidation
Acetyl COA
TCA
Oxidative Phosphorylation

MITO FATO

Question 2

Metabolism on both the mitochodria and cytoplasm

Answer 2

Heme
Urea
Gluconeogenesis

“HUG BOTH”

Question 3

Fatty acid (cholesterol) synthesis happens where?

Answer 3

LIVER

Question 4

Enzyme: Acetyl COA –> HMG COA

Answer 4

HMG COA synthase

Question 5

Rate limiting enzyme in fatty acid synthesis

Answer 5

HMG COA reductase

Question 6

What type of synthesis?

Acetyl COA–>HMG COA

Answer 6

Ketogenesis

Question 7

Mode of action of Statins

Answer 7

HMG COA reductase inhibitor

Question 8

Types of Ketone bodies

Answer 8

Acetone
Acetoacetate
Hydroxybutiric acid

Question 9

What type ketone bodies is associated with DKA?

Answer 9

Hydroxybutiric acid

Question 10

Spontaneous decaboxylation of acetoacetate produces what?

Answer 10

ACETONE

Question 11

In uncontrolled DM/Starvation, 75% of ketone bodies is utilized for energy by this organ

Answer 11

BRAIN

Question 12

net ATP generated in the B-hydroxybutirate

Answer 12

26 ATPs

Question 13

Beta oxidation happens where? and what is the biproduct?

Answer 13

Mitochondria, Acetyl COA

Question 14

Fatty acid synthesis happens where? What does it produce?

Answer 14

Cytoplasm; palmitate

Question 15

reversible inhibitor of Lipases

Answer 15

Orlistat

Question 16

Where is glycogen mostly stored?

Answer 16

Muscle

Question 17

Rate limiting enzyme in glycogenolysis

Answer 17

Glycogen phosphorylase

Question 18

Glucose 1-phosphate —> G-6-phosphate enzyme

Answer 18

Phophoglucomutase