Metabolic Stress Flashcards
what is MS
response to severe injury or disease
is MS catabolic or anabolic
catabolic
breaks down macros for energy
conditions that cause MS
trauma
surgery
burns
sepsis
what happens in Ms that causes all the issues
REE spikes
which hormones are counteract insulin
glucagon
catecholamines = epi, norepi
glucocorticoids =cortisol
what are the stress h
cortisol
ACTH
NE
epi
insulin and glucagon in stress
insulin lowers
glucagon increases = energy
how is cho metabolism during stress
- insulin resistance
- hyperglycemia
- anaerobic glycolysis
why do u see so much REE in MS
the metabolic systems in place (CHO metabolism) arent effecient
in MS, what increases? NAPP or PAPP?
PAPP increases bc released due to cytokines
NAPP decreases
example of NAPP
albumin
prot metabolism in MS
- increased AA efflux
- negative N balance
why is there so much AA efflux in PRO met in MS
- gluconeogensis
- protein synthesis (PAPP)
- gut fuel glutamine
lipid metabolism in MS
- lipolysis
- FFA
- changes in RQ
what does RQ tell u
info about metabolism state
high RQ = cho higher
low RQ = fat being used as fuel source = not norm
