Metabolic Disorders: DM and liver disorders Flashcards

0
Q

What is Type 1 DM?

A

Beta cell destruction, leading to absolute insulin deficiency

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1
Q

What is DM?

A

A group of metabolic diseases characterized by hyperglycemia resulting from deficits in insulin secretion, insulin action, or both.

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2
Q

What is Type 2 diabetes?

A

Insulin resistance.

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3
Q

What are the S/S of DM?

A

Polyphagia, polydipsia, and hunger

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4
Q

When is the onset for type 1 DM?

A

Juvenile onset diabetes.

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5
Q

What happens in type 1 DM?

A

It is autoimmune, the beta cells are destroyed, causing loss of insulin production.

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6
Q

What happens when you have less insulin?

A

Your sugar goes up (NO BUS) , along with lipids and ketones form, (DKA), causes you to be less hungry and lose weight.

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7
Q

What age group does type II DM affect?

A

Adult onset. Correlated with age, obesity,and family history.

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8
Q

What happens to the insulin in type II DM?

A

Increase in insulin secretion to compensate for peripheral tissue resistance. (In the end this system fails though because the pancreas will burn out, and they will need insulin as well)

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9
Q

What is normal fasting blood glucose?

A

70-100mg/dL

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10
Q

What does Hb1Ac measure?

A

Will tell you glucose level over the past 4 months (normal is less than 6.5%)

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11
Q

Hyperglycemia diagnostics: what fasting plasma glucose level indicates hyperglycemia?

A

Greater than 100

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12
Q

Hyperglycemia diagnostics: what level of a random blood glucose indicates hyperglycemia?

A

Greater than 126 with polyuria and polydipsia

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13
Q

Hyperglycemia diagnostics:what oral glucose tolerance test indicates hyperglycemia?

A

1 hour: less than 200mg/dL.

2 hours: less than 140mg/dL

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14
Q

What are the adrenergic s/s for hypoglycemia?

A

Diaphoresis, sweating, hunger, headache and anxiety

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15
Q

What are neuroglucopenic s/s of hypoglycemia?

A

Confusion, slurred speech, coma and seizure.

16
Q

What is the only thing that feeds your brain?

A

GLUCOSE!:)

17
Q

What is the onset of hypoglycemia/shock?

A

Rapid

18
Q

What are the symptoms of hypoglycemia/shock?

A

Weak, anxious, confused and tachycardia

19
Q

What is the skin like in hypoglycemia/shock?

A

Perspiring

20
Q

What are the mucous membranes like in hypoglycemia/shock?

A

Normal

21
Q

What are the respirations like in hypoglycemia/shock?

A

Normal

22
Q

Who is at risk for hypoglycemia/shock?

A

Type I and type II DM, insufficient food intake, excessive exercise, and excessive insulin.

23
Q

What is the blood sugar in hypoglycemia/shock?

A

Newborns: 30mg/dL or less
Adults: 60mg/dL or less

24
Q

What is the Tx for hypoglycemia/shock?

A

Fast acting carbohydrate, IV glucose, subcutaneous glucagon

25
Q

What is the onset for DKA?

A

Slow

26
Q

What are the symptoms of DKA?

A

N/V, polyuria, polyphagia, polydipsia, headache, irritable, comatose, fruity great odor, and SOB

27
Q

What is the skin like in DKA?

A

Hot, flushed, and dry

28
Q

What are the mucous membranes like in DKA?

A

Dry

29
Q

What are the respiration like in DKA?

A

Hyperventilation

30
Q

Who is at risk for DKA?

A

Type I DM, stressful situation

31
Q

What is the blood sugar in DKA?

A

Greater than 250mg/dL

32
Q

What is the Tx for DKA?

A

Low dose insulin, electrolyte and fluid replacement.

33
Q

What occurs in diabetes?

A

There is either decreased insulin secretion, or insensitivity to insulin, therefore glucose can’t be driven into the cell and hyperglycemia and osmotic diuresis can occur.

34
Q

What happens with increased lipid levels?

A

Body uses free fatty acids for energy and ketones are produced (which cause high lipid levels!)

35
Q

What does high lipid levels result in?

A

DKA