Metabolic Disorders: DM and liver disorders Flashcards
What is Type 1 DM?
Beta cell destruction, leading to absolute insulin deficiency
What is DM?
A group of metabolic diseases characterized by hyperglycemia resulting from deficits in insulin secretion, insulin action, or both.
What is Type 2 diabetes?
Insulin resistance.
What are the S/S of DM?
Polyphagia, polydipsia, and hunger
When is the onset for type 1 DM?
Juvenile onset diabetes.
What happens in type 1 DM?
It is autoimmune, the beta cells are destroyed, causing loss of insulin production.
What happens when you have less insulin?
Your sugar goes up (NO BUS) , along with lipids and ketones form, (DKA), causes you to be less hungry and lose weight.
What age group does type II DM affect?
Adult onset. Correlated with age, obesity,and family history.
What happens to the insulin in type II DM?
Increase in insulin secretion to compensate for peripheral tissue resistance. (In the end this system fails though because the pancreas will burn out, and they will need insulin as well)
What is normal fasting blood glucose?
70-100mg/dL
What does Hb1Ac measure?
Will tell you glucose level over the past 4 months (normal is less than 6.5%)
Hyperglycemia diagnostics: what fasting plasma glucose level indicates hyperglycemia?
Greater than 100
Hyperglycemia diagnostics: what level of a random blood glucose indicates hyperglycemia?
Greater than 126 with polyuria and polydipsia
Hyperglycemia diagnostics:what oral glucose tolerance test indicates hyperglycemia?
1 hour: less than 200mg/dL.
2 hours: less than 140mg/dL
What are the adrenergic s/s for hypoglycemia?
Diaphoresis, sweating, hunger, headache and anxiety