Metabolic Disorders

Question 1

Von gierkes disease

Answer 1

GSD type 1 : glu 6 phosphatase deficiency
Like fatty infiltration in usg
Additional more prone for hepatic adenoma/HCC
Hepatomegaly, nephromegaly, hypoglycemia

Question 2

Cirrhosis

Answer 2

Volume redistribution: caudate and left lobe relative enlargement
CL:RL: more than 0.6
Nodular surface
Heterogeneous echotexture
Nodules: regeneration: echogenic walls: more iron in GRE in MRI
Dysplastic: larger than 10mm, portal vein supply diff from HCC
Causes : alcohol, chronic hepatitis, biliary cirrhosis, Wilson, primary sclerosis cholangitis, hemochromatosis
Doppler in compensated cirrhosis:
Hep vein normally tripasic wave form
In cirrhosis: decreased amplitude and loss of retrograde flow and flat wave, structure: aliasing
Artery : loss of increase in resistive index after meals