Metabolic Conditions Flashcards

S2Q3

1
Q

METABOLIC:

etiology (3), risk factors (5)

prevention - exercise duration & intensity, diet (2)

A
  • eti: sedentary, obesity, insulin resistance (DM2)
  • risk factors: age, race, obesity, DM, PCOS

prevention
* exercise: mild-mod 30-60 mins
* low salt & fat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

METABOLIC: Manifestation

abdominal obesity (2), waist circumference (2)

hyperglycemia - fasting, pre, DM

HDL, LDL

Htn

other sx (4)

A
  • abdominal obesity & HDL: 40 (M) 35 (F)
  • LDL: 130
  • waist circumference: 88 (M) 102 (F)

hyperglycemia
* fasting blood sugar & Htn: 110

HBAIC (3m)
* pre-DM: 5.7-6.4
* DM: >6.5

other sx: polyuria, polydypsia (thirst), blur, fatigue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

METABOLIC:

what + what = electrolyte balance

A

thirst mechanism & renal = balance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

METABOLIC: Conditions - Dehydration

prognosis (2)

sx (8)

sx: poor skin, headache

A
  • prognosis: lead to uremia (toxin in blood), hypovolemic shock (rapid fluid loss = organ failure)

signs/sx
* poor skin turgor, dry mucous membrane
* headache, irritability, disorientation, lethargy
* postural hypotension
* incoordination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

METABOLIC:

poor skin turgor is what

A

poor skin turgor = remain elevated after pulled & released

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

METABOLIC: Conditions - Edema

etiology (8)
sx (3)

sx: weight gain

eti: heart failure, protein

A

causes
* heart failure (R>L), venous insufficiency, obstructed lymph
* protein kidney loss, liver cirrhosis
* pre-menstrual retention, pregnancy
* heat stress
* burns, inflammation, allergy

signs/sx
* weight gain, cramps, twitches

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

METABOLIC: Conditions - Potassium

hypokalemia - etiology (6), sx (4)

hyperkalemia - etiology (5)

sx (2)

hypo - metaolic acidosis + FAND; hyper - metabolic acidosis

A

hypokalemia
causes
- metabolic acidosis, alkalosis
- renal tubular disease
- diarrhea, vomit, diuretic
signs/sx
- arrythmia (depressed ST), weakness
- fatigue, aches, nausea, abdominal distention

hyperkalemia
causes
- metabolic acidosis, diabetic ketoacidosis
- kidney failure, sickle cell, SLE
signs/sx
- arrythmia (tall T), weakness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

METABOLIC: Conditions - Sodium

hypo - etiology (2), sx (4)

hyper - etiology (1), sx (3)

sx (2)

eti - water; sx - ICP & pitting edema

A

hyponatremia
causes
- water intoxication, endocrine tumor
signs/sx
- convulsion, weight loss
- inc ICP, cerebral hemorrhage, incoordination, sleepy

hypernatremia
causes
- water deficit
signs/sx
- convulsion, weight gain
- active heart (tachy Htn agitate), pitting edema, pulmonary edema c dyspnea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

METABOLIC: Conditions - Calcium

hypo - etiology (5.2), sx (6.2.1)

hyper - etiology (1.3), sx (4)

sx (1)

eti - parathyroid/acute; sx - muscle cramps & pagod

A

hypocalcemia
causes
- hypoparathyroidism, dec albumin, malabsorption of Ca & vit D
- hyperphyphatemia
- alkalosis, acute pancreatitis
signs/sx
- arrythmia
- muscle cramps, twitch, tetany, spasm, convulsion, paresthesia
- anxiety, irritability
- hypotension

hypercalcemia
causes
- hyperparathyroidism, hyperthyroidism, vit. A intoxication
- tumor
signs/sx
- arrythmia
- pagod (nausea vomit fatigue), depression, confusion
- inc urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

METABOLIC: Conditions - Magnesium

hypo - etiology (8), sx (2)

hyper - etiology (3.3), sx (4.2)

sx (1)

eti - Ca (3) edema (2) & diabetic; sx - cramps & hyporeflexive

A

hypomagnesemia
causes
- hypoparathyroidism, malabsorption, chronic pancreatitis
- liver cirrhosis, hemodialysis, blood transfusion, fluid loss
- severe burn
signs/sx
- confusion
- leg & foot cramps, irritability

hypermagnesemia
causes
- diabetic acidosis, renal failure, hypothyroidism
- addison’s, antacids, dehydration
signs/sx
- confusion
- weak, lethargy, drowsy, hyporeflexia
- bradycardia, hypotension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

METABOLIC: Conditions - Chloride

hypo - etiology (3.2.4), sx (3)

hyper - etiology (3.3), sx (3)

sx (2)

eti - alkalosis/CHF & alkalosis; sx - breathing & thirst

A

hypochloremia
causes
- metabolic alkalosis, CHF, chronic lung disease
- prolonged diarrhea/vomit
- diuretics, laxatives, corticosteroid, bicarbonate
signs/sx
- weak, fatigue
- fluid loss, hyponatremia, diff breathing

hyperchloremia
causes
- respiratory alkalosis, kidney, DM
signs/sx
- weak, fatigue
- inc BP, thirst, dry mucous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

METABOLIC: Conditions - Phosphate

hypo - etiology (3.4.2), sx (3.2)

hyper - etiology (4.3), sx (3)

sx (3)

eti - Ca (2) genetics & Ca (2); sx - bone shit

A

hypophosphatemia
causes
- hyperparathyroidism, vit D. deficiency
- genetics, alcohol, fanconi’s syndrome, diabetic ketoacidosis
- chronic diarrhea
- severe burns, ICU
signs/sx
- weakness, bone pain, bone fx
- slowed growth, teeth decay or late baby
- numb, irritability, confused

hyperphosphatemia
causes
- kidney, hypoparathyroidism, vit. D excess, diabetic ketoacidosis
- muscle & cell damage, infection
signs/sx
- weakness, joint pain, bone weak
- numb & tingling around mouth
- rash, itchy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

METABOLIC: Conditions - Acid-Base

metabolic acidosis - etiology (3), sx (3.2)

metabolic alkalosis - etiology (2.3), sx (3.3)

sx (4)

sx- malaise & coma

A

metabolic acidosis
causes
- DM, renal insufficiency, diarrhea
signs/sx
- vomit, muscle twitch
- hyperventilation, deep respiration
- headache, nausea, malaise
- dry skin, poor turgoe

metabolic alkalosis
causes
- hypokalemia, peptic ulcer
- antacids, diuretics, excess vomit
signs/sx
- vomit, muscle twitch
- hypoventilation, depressed respiration
- irritability, agitation, confusion
- dysrrhytmia, weakness, coma (death)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

METABOLIC: Conditions - Thyroid

hypo - etiology (2), sx (3), red flags (4)

hyper - etiology (3), sx (1.5), red flags (2)

sx (3)

which can lead to death

sx - dry lethargy & tremor

A

hypothyroidism
causes
- anti-thyroid meds, hashimoto’s disease
signs/sx
- weight gain, cold intolerance, constipation
- dry skin & hair, mental & physical lethargy, low BP
red flags
- can lead to death
- exercise intolerance, exercise myalgia, apathy, weak

hyperthyroidemia
causes
- inc thyroxine (grave’s disease & thyroid storm), inc metabolism
signs/sx
- weight loss, heat intolerance, hunger
- diarrhea
- nausea, palpitation, tachy, hypereflexive, tremor
red flags
- exercise intolerance, fatigue (hypermetabolic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

METABOLIC: Conditions - Adrenal

addison’s - pathology (1=2), etiology (3), sx (2.2.3), tx (5)

sx: bronze anorexia stress

A
  • bye adrenocortical = bye cortisol & aldosterone
  • eti: infection, neoplasm, hemorrhage

signs/sx
- inc bronze skin, cold intolerance
- anxiety, depression, stress intolerance
- dec endurance, anorexia

tx
- glucocorticoid
- Na K, carbs & protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

METABOLIC - Condition: Adrenal Disorders

cushing - pathology (2), etiology (1), sx (10), tx (2.3)

sx: glucose

A
  • inc cortisol & glucocorticoids
  • eti: pituitary tumor

signs/sx
- dec glucose tolerance, moon fascie, buffalo hump, abdominal & chest obesity
- dec testosterone & menstrual period
- atrophy, edema, hypokalemia
- emotional lability

tx
- excision, irradiation
- monitor: fluids, electrolytes, weight

17
Q

METABOLIC:

DM triad

destroys what

A

polydypsia
polyuria
polyphagia

destroy nerves (thigh)

18
Q

METABOLIC:

Mg Cl phosphate purpose (2.2.5)

which 1st & 2nd highest amount

A

Mg - protein & energy

Cl - electrolyte, acid base

phosphate - muscle nerve bone ATP DNA/RNA

Mg > Cl

19
Q

METABOLIC: Others

gaucher’s (1=3=2=1)

A

can’t break down fat = accumulate in liver spleen marrow = pain & bone damage = death

20
Q

METABOLIC: Others

maple syrup (3=1=1)

A

disrupt metabolism of amino acids (valine leucine isoleucine) = rapid neuron degeneration = death within months p birth

21
Q

METABOLIC: Others

diabetic insipidus - other name (2), patho (1=1), structure, central

A

primary polydypsia/dipsogenic

  • drink many fluid = diluted/hypotonic urine
  • hypothalamus
  • central: lack of vasopressin
22
Q

METABOLIC: Others

DM - type I vs. II patho age preventable tx, sx (7)

A

TYPE I
- pancreas no insulin
- young age
- not preventable
- require insulin therapy

TYPE II
- insulin resistance
- older age
- preventable via life modification

sx:
- weight loss, hunger, thirst, urine, numb & tingling hand & foot, blurry vision, wounds

23
Q

METABOLIC

K Na Ca Mg Cl Phosphate pH

A

3.5-5.5
135-146
8.4-10.4
1.8-2.4
98-107
36-92
7.35-7.45