Meta Analysis

Question 1

5 steps on Evidence-Based Practise

Answer 1

• Patient with problems
• Formulate answerable clinical questions
• Search for the evidence
• Critical Appraisal
• Apply the evidence

Question 2

Steps of a Systematic

Review following Cochrane Methods

Answer 2

Identification, selection, abstraction, analysis

Question 3

How to read and appraise SR

Answer 3

Validity: The (Q)FAITH Tools
Question, Find, Appraise, Include, Total Up, Heterogenity

Importance
Applicability

Question 4

Total Up

Answer 4

Apakah hasil studi tersebut dipresentasikan dengan baik

Question 5

Method section isinya?

Answer 5

Kriteria inklusi, eksklusi, studi design

Question 6

Publication Bias

Answer 6

-Studi dengan hasil negatif sering 
tidak dipublikasikan
-disubmit di jurnal lokal
-jumlah sampel kecil
Dipengaruhi farmasi

Solusi:

• inception di trial registers
• …
• Funnel Plot: to assess publication bias in MA

Question 7

Small sudy effect

Answer 7

outcome yg kita teliti memiliki sampel size yg kecil
- Fixed effext model: Effect estimate dipengaruhi bobot tiap studi –> makin besar sample size –> bobot lebih besar

• random effect model: memungkinkan sample size kecil bs berefek jg

Question 8

Bias pada SR-MA

Answer 8

Publication Bias

7 Domain:
- Selection Bias: random, allocation
- Performance Bias: blinding (participants, personel)
-