Mesencephalon Flashcards
The cerebral peduncle
represents axons for ascending and descending pathways in the brainstem.
The mesencephalic tegmentum contains many key nuclei, including:
- the substantia nigra
- the periaqueductal grey
- the red nucleus
- ventral tegmental area (VTA)
substantia nigra
(damaged in Parkinson’s Disease); axons terminate in striatum, releasing dopamine that is important to the selection/initiation of motor sequences.
periaqueductal grey
surrounding the cerebral aqueduct; this region is involved in gating of pain information from the spinal cord.
the red nucleus
receives inputs from cortical motoneurons and cerebellum; output to cerebellum via inferior olivary nucleus and to spinal cord; involved in smooth movement of limbs and digits as a group.
ventral tegmental area (VTA);
axons terminate in the nucleus accumbens (reward/reinforcement) and the hippocampus and prefrontal cortex (emotion/cognition)