Meropenen Flashcards

1
Q

Vía de administración

A

Parenteral IV

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2
Q

Distribución y absorción

A

Se distribuye en todos los tejidos incluyendo SNC

t 1/2 1 hora - 1 hora 30 minutos

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3
Q

Excreción

A

Renal

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4
Q

Clasificación embrazo

A

B

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5
Q

Mecanismo de acción

A

Inhibe la transpeptidasa y activa enzimas hidrolíticas

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6
Q

Riesgo en combinación

A

ácido valproico, aumenta riesgo de crisis epilépticas

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7
Q

Indicaciones terapéuticas

A

Meningitis bacteriana
Infecciones complicadas en piel y tejido subcutáneo
Infecciones complicadas en abdomen
Abarca Gram+, Gram-, Pseudomonas y anaerobios

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8
Q

Contraindicaciones

A

Hipersensibilidad

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9
Q

Efectos adversos

A

Concentraciones elevadas causan convulsiones
Síndrome de S-J
Colitis pseudomembranosa

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