Meperidine (Demerol)

Question 1

Meperidine (Demerol)

Class

Answer 1

Opioid analgesic

Question 2

Meperidine (Demerol)

Mechanism of Action

Answer 2

Synthetic opioid analgesic that acts on opioid receptor sites to produce analgesia, Scheduled narcotic

Question 3

Meperidine (Demerol)

Indications

Answer 3

Analgesia for moderate to severe pai

Question 4

Meperidine (Demerol)

Contraindications

Answer 4

Hypersensitivity to narcotics, diarrhea caused by poisoning, patients taking MAOIs, during labor or delivery of a premature infant, undiagnosed abdominal pain or head injury

Question 5

Meperidine (Demerol)

Adverse Reactions

Answer 5

Do not give concurrent with MAOIs, exacerbates CNS depression

Question 6

Meperidine (Demerol)

Adult Dosage

Answer 6

Adult: 50 – 100 mg IM, SC or 25 – 50 mg slow IV

Question 7

Meperidine (Demerol)

Pediatric Dosage

Answer 7

Pediatric: 1 – 2 mg/kg/dose IV, IO, IM, SC

Question 8

Meperidine (Demerol)

Onset

Answer 8

IM 10 – 45 minutes, IV immediate

Question 9

Meperidine (Demerol)

Peak Effect

Answer 9

30 – 60 minutes

Question 10

Meperidine (Demerol)

Duration

Answer 10

2 – 4 hours

Question 11

Meperidine (Demerol)

Special Consideration

Answer 11

Naloxone should be readily available

Question 12

Meperidine (Demerol)

Adverse Reactions

Answer 12

Respiratory depression, sedation, apnea, circulatory depression, arrhythmias, shock, increased ICP