mental meds Flashcards

1
Q

Selective serotonin reuptake inhibitors (SSRIs) meds (5)

A

Fluoxetine, Paroxetine, Sertraline, Citalopram, Escitalopram

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2
Q

SSRIs MOA

A

Blocks the reuptake of serotonin

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3
Q

SSRI common side effects (6)

A

anxiety, insomnia, sedation, akathisia, sexual dysfunction, increased risk of suicide

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4
Q

What is serotonin syndrome?

A

Serotonin syndrome occurs when you take medications that cause high levels of the chemical serotonin to accumulate in your body.

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5
Q

How can MILD serotonin syndrome be fixed?

A

Milder forms of serotonin syndrome may go away within a day of stopping the medications that cause symptoms and, sometimes, after taking drugs that block serotonin.

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6
Q

Serotonin syndrome side effects

A

agitation, sweating, fever, tachycardia, hypotension, rigidity, hyperreflexia, confusion, coma and death.

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7
Q

SSRI nursing considerations

A
  • Takes 4 weeks for full therapeutic effect. Some improvement in 2-3 weeks.
  • Take w/ food to minimize nausea
  • Sedation, take at bedtime
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8
Q

Tricyclic antidepressants (2)

A

Amitriptyline, and Imipramine

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9
Q

Tricyclic antidepressants MOA

A

Block reuptake of norepinephrine and serotonin to some degree

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10
Q

Tricyclic antidepressant side effects

A
  • Weight gain

- Anticholinergic side effect such as, dry mouth, urinary retention, constipation, vision changes

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11
Q

Tricyclic antidepressant nursing considerations

A

These medications take 4-6 weeks for full effectiveness

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12
Q

TETRAcyclic antidepressants (1)

A

Mirtazapine

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13
Q

TETRAcyclic antidepressants MOA

A

antagonizes alpha-2 adrenergic and serotonin 5-HT2 receptors

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14
Q

TETRAcyclic antidepressants COMMON side effects

A

somnolence (drowsiness/sleepy), xerostomia (dry mouth), increased appetite, and weight gain

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15
Q

TETRAcyclic antidepressants SERIOUS side effects

A

agranulocytosis (low WBC), serotonin syndrome, orthostatic hypotension, seizures, akathisia, torsade de points and Steven-Johnson syndrome

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16
Q

What is torsade de points? What side effect medication is it associated with?

A

TETRAcyclic antidepressants

-polymorphic ventricular tachycardia characterized by a gradual change in amplitude and twisting of the QRS complexes around an isoelectric line on the electrocardiogram.

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17
Q

What is Steven-Johnson’s syndrome?

A

SJS is a rare, serious disorder of the skin and mucous membranes. It’s usually a reaction to medication that starts with flu-like symptoms

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18
Q

What are the symptoms of SJS?

A

Flu-like symptoms, fever, rash, blisters, peeling of skin and rhabdomyolysis (muscle break-down)

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19
Q

TETRAcyclic antidepressants nursing considerations

A

LABS: CBC, liver function tests (LFTs), blood glucose, cholesterol

monitor weight and suicide risk

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20
Q

TETRAcyclic antidepressants nursing considerations

A

LABS: CBC, liver function tests (LFTs), blood glucose, cholesterol

monitor weight and suicide risk

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21
Q

Serotonin norepinephrine reuptake inhibitors (SNRIs) drugs (3)

A

Venlafaxine, Duloxetine, Atomoxetine

-ine endings

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22
Q

SNRIs MOA

A

Block reuptake of norepinephrine and serotonin

23
Q

SNRIs SERIOUS side effects

A

suicide, serotonin syndrome, HTN, EPS, seizures

24
Q

SNRIs COMMON side effects

A

insomnia, abnormal dreams, anxiety, sexual dysfunction, anorexia, n/v, and weight loss

25
SNRIs monitor labs...
creatinine at baseline, lipid panel if on long term
26
SNRIs monitor for ?
suicide, BP, monitor height/weight in children
27
Atomoxetine (SNRI) is used for?
ADHD, not a stimulant
28
Miscellaneous antidepressants (2)
Burpoprion and Trazodone
29
Miscell. antidepressants are?
Norepinephrine dopamine reuptake inhibitors (NDRIs)
30
NDRIs MOA
inhibits uptake of norepinephrine and dopamine
31
NDRIs SERIOUS side effects
suicide, HI, HTN, arrhythmias, MI, hepatotoxicity, seizures
32
NDRIs COMMON side effects
Xerostomia, diaphoresis, abnormal dreams, insomnia, tinnitus, anorexia, weight loss and anxiety.
33
NDRIs monitor for?
suicide and BP
34
NDRIs labs
creatinine at baseline
35
MAOI drugs (2)
phenelzine, tranylcypromine
36
MAOIs MOA
interfere with metabolism of enzyme
37
MAOI side effects
sedation, insomnia, weight gain, dry mouth, orthostatic hypotension, sexual dysfunction
38
MAOI SERIOUS side effect
HTN crisis due to tyramine ingestion
39
Tyramine sources:
aged cheeses, aged meats/cold cuts , tofu, avocado, tap/microbrew beer, soy sauce, yogurt, sour cream, brewers yeast and MSG
40
Mood stabilizer drug (1)
Lithium
41
Lithium MOA
Normalizes reuptake of serotonin, norepinephrine, acetylcholine, and dopamine
42
Lithium side effects
anorexia, nausea, hand tremors, polydipsia/uria, metallic taste in mouth, fatigue, weight gain, acne
43
Lithium toxicity
severe diarrhea, vomiting, drowsiness, muscle weakness, lack of coordination, coma/death
44
Lithium labs:
1.5 or HIGHER is lithium toxicity. safe range: 0.6 - 1.2 monitor everyday for 2-3 days then monthly
45
Anticonvulsant mood stabilizers (2)
Valproic acid and carbamapezine
46
Valproic acid and carbamapezine MOA
unknown, increase levels of GABA. Inhibits kindling process of seizures
47
Valproic acid and carbamapezine side effects
drowsiness, sedation, dry mouth, blurred vision, rashes, orthostatic hypotension, weight gain, alopecia and hand tremors
48
Valproic acid and carbamapezine labs:
liver function at baseline periodically (3-6 months) requires blood levels take with meals to decrease nausea
49
Sensitizing agent for alcohol
disulfiram
50
Disulfiram MOA
inhibits enzyme aldehyde dehydrogenase, needed for ethanol metabolism
51
disulfiram COMMON side effects
rash, drowsiness, impotence, headache, acne, metallic taste
52
disulfiram SERIOUS side effects
hepatoxicity, psychosis, peripheral neuropathy, optic neuritis
53
disulfiram labs
liver functions at baseline | after 10-14 days, CBC, serum chemistries
54
disulfiram teaching
all sources of alcohol in diet, mouthwash, aftershave, cologne, cough preparations, vanilla, and to READ LABELS