mental meds Flashcards
Selective serotonin reuptake inhibitors (SSRIs) meds (5)
Fluoxetine, Paroxetine, Sertraline, Citalopram, Escitalopram
SSRIs MOA
Blocks the reuptake of serotonin
SSRI common side effects (6)
anxiety, insomnia, sedation, akathisia, sexual dysfunction, increased risk of suicide
What is serotonin syndrome?
Serotonin syndrome occurs when you take medications that cause high levels of the chemical serotonin to accumulate in your body.
How can MILD serotonin syndrome be fixed?
Milder forms of serotonin syndrome may go away within a day of stopping the medications that cause symptoms and, sometimes, after taking drugs that block serotonin.
Serotonin syndrome side effects
agitation, sweating, fever, tachycardia, hypotension, rigidity, hyperreflexia, confusion, coma and death.
SSRI nursing considerations
- Takes 4 weeks for full therapeutic effect. Some improvement in 2-3 weeks.
- Take w/ food to minimize nausea
- Sedation, take at bedtime
Tricyclic antidepressants (2)
Amitriptyline, and Imipramine
Tricyclic antidepressants MOA
Block reuptake of norepinephrine and serotonin to some degree
Tricyclic antidepressant side effects
- Weight gain
- Anticholinergic side effect such as, dry mouth, urinary retention, constipation, vision changes
Tricyclic antidepressant nursing considerations
These medications take 4-6 weeks for full effectiveness
TETRAcyclic antidepressants (1)
Mirtazapine
TETRAcyclic antidepressants MOA
antagonizes alpha-2 adrenergic and serotonin 5-HT2 receptors
TETRAcyclic antidepressants COMMON side effects
somnolence (drowsiness/sleepy), xerostomia (dry mouth), increased appetite, and weight gain
TETRAcyclic antidepressants SERIOUS side effects
agranulocytosis (low WBC), serotonin syndrome, orthostatic hypotension, seizures, akathisia, torsade de points and Steven-Johnson syndrome
What is torsade de points? What side effect medication is it associated with?
TETRAcyclic antidepressants
-polymorphic ventricular tachycardia characterized by a gradual change in amplitude and twisting of the QRS complexes around an isoelectric line on the electrocardiogram.
What is Steven-Johnson’s syndrome?
SJS is a rare, serious disorder of the skin and mucous membranes. It’s usually a reaction to medication that starts with flu-like symptoms
What are the symptoms of SJS?
Flu-like symptoms, fever, rash, blisters, peeling of skin and rhabdomyolysis (muscle break-down)
TETRAcyclic antidepressants nursing considerations
LABS: CBC, liver function tests (LFTs), blood glucose, cholesterol
monitor weight and suicide risk
TETRAcyclic antidepressants nursing considerations
LABS: CBC, liver function tests (LFTs), blood glucose, cholesterol
monitor weight and suicide risk
Serotonin norepinephrine reuptake inhibitors (SNRIs) drugs (3)
Venlafaxine, Duloxetine, Atomoxetine
-ine endings